Join the Pathfinder 2 Study to Find Cancer Early

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Help improve cancer early detection

Too often, cancer isn’t found until it’s advanced and harder to treat. Worrying about having cancer can also feel overwhelming. Taking steps to find cancer early can help you feel more in control of your health. Finding cancer early also improves the chance of survival.

A blood test designed to detect many cancer types

The Pathfinder 2 study will check how well an early test called Galleri® detects many cancer types. It uses a simple blood draw.

This test is being studied and is not approved or cleared by the Food and Drug Administration. It is not meant to replace cancer screening tests your health care provider may recommend, such as colonoscopy or mammography.

OHSU is a national study site

The OHSU Knight Cancer Institute is a national study site selected by GRAIL, Inc., a health care company dedicated to detecting cancer early. The study aims to improve early cancer detection.

Dr. Tom Beer, deputy director of the Knight Cancer Institute, oversees the study locally. Dr. Beer is also chief medical officer for the institute's Cancer Early Detection Advanced Research, CEDAR, center.

Who can take part?

The Pathfinder 2 study is open to those who:

  • Are 50 or older and
  • Have never been diagnosed with cancer or
  • Have been cancer-free at least three years.

Participants in previous or ongoing GRAIL-sponsored studies are not eligible.

What will I do?

You will be asked to:

  • Contact the study team to see if you are eligible to enroll.
  • If eligible, read and sign an informed consent form that fully explains the study.
  • Provide your medical history and allow the OHSU team access to your medical records.
  • Give a blood sample (40 ml; about 1.3 ounces), drawn by a trained practitioner at OHSU.
  • Complete a questionnaire around the time you have the Galleri test.
  • Expect to receive your Galleri test result from the study team within 30 days after your blood is drawn.
  • Complete 2-3 more questionnaires.

If you choose to take part in the Pathfinder 2 study, it is important that you follow your health care provider’s recommendations for any cancer screening tests, such as colonoscopy or mammography. Missing recommended screening or ignoring symptoms could delay a cancer diagnosis.

How to enroll

Contact a study coordinator at OHSU:

Please let us know if you prefer to be contacted by phone or email. 

How to enroll

Contact a study coordinator:

Please let us know if you prefer to be contacted by phone or email.

Did you take part in the Pathfinder 1 study at OHSU?

If you have any questions, contact a study coordinator:

Hear from a Pathfinder 1 study participant

Tami Beaty is no stranger to cancer.

“I thought that the team did a really good job. We were very impressed with the questions that were asked, and the blood test was painless."

Tami Beaty