Join the Pathfinder 2 Study to Find Cancer Early
Help improve cancer early detection
Too often, cancer isn’t found until it’s advanced and harder to treat. Worrying about having cancer can also feel overwhelming. Taking steps to find cancer early can help you feel more in control of your health. Finding cancer early also improves the chance of survival.
A blood test designed to detect many cancer types
The Pathfinder 2 study will check how well an early test called Galleri® detects many cancer types. It uses a simple blood draw.
This test is being studied and is not approved or cleared by the Food and Drug Administration. It is not meant to replace cancer screening tests your health care provider may recommend, such as colonoscopy or mammography.
OHSU joins with other sites to recruit 20,000 participants
The OHSU Knight Cancer Institute is a national study site selected by GRAIL, Inc., a health care company dedicated to detecting cancer early. The study aims to improve early cancer detection.
Dr. Nima Nabavizadeh, associate professor of radiation medicine at the Knight, is the principal invesgitagor of the study.
Who can take part?
The Pathfinder 2 study is open to those who:
- Are 50* or older and
- Have never been diagnosed with cancer or
- Have been cancer-free at least three years.
Participants in previous or ongoing GRAIL-sponsored studies are not eligible.
*At this time we are directing our enrollment focus toward certain groups that are currently underrepresented in the Pathfinder 2 study population and have halted recruitment of Caucasian individuals ages 50-59. Read about our diversity initiatives here.
What will I do?
You will be asked to:
- Contact the study team to see if you are eligible to enroll.
- If eligible, read and sign an informed consent form that fully explains the study.
- Provide your medical history and allow the team access to your medical records.
- Give a blood sample (40 ml; about 1.3 ounces), drawn by a trained practitioner.
- Complete a questionnaire around the time you have the Galleri test.
- Expect to receive your Galleri test result from the study team within 30 days after your blood is drawn.
- Complete 2-3 more questionnaires.
If you choose to take part in the Pathfinder 2 study, it is important that you follow your health care provider’s recommendations for any cancer screening tests, such as colonoscopy or mammography. Missing recommended screening or ignoring symptoms could delay a cancer diagnosis.
How to enroll
The Knight Cancer Institute is coordinating with health care organizations across Oregon to offer the Pathfinder 2 study in a variety of locations. Contact a study coordinator to learn more:
OHSU Knight Cancer Institute in the Portland metro
Bay Area Hospital in Coos Bay
One Community Health in Hood River and The Dalles
Salem Health in Salem
St. Charles Health System in Bend, Madras, Redmond, and Prineville
Read more from study sponsor GRAIL
How to enroll
Questions? Contact our team:
Did you take part in the Pathfinder 1 study at OHSU?
If you have any questions, contact a study coordinator:
Hear from a Pathfinder 1 study participant
“I thought that the team did a really good job. We were very impressed with the questions that were asked, and the blood test was painless."
Learn more about clinical trials
Watch this video to find out how clinical trials work and why they're important.