OHSU Knight Cancer Institute

About the Knight Cancer Institute

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The OHSU Knight Cancer Institute is driven by a single mission: to end cancer as we know it.

We are a team of hundreds of doctors, nurses, scientists and other professionals who have earned a national reputation for excellence. Every year, we treat about 6,000 patients and conduct about 1,400 research projects, including more than 400 clinical trials.

Our research has led to groundbreaking advances in targeted therapy, immunotherapy and other ways to fight cancer. We're also working on new ways to find cancer early, when it’s easier to treat. We’re working to free the world from the burden of cancer, one patient at a time.

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For patients and families

We’re here for you. Your team of specialists will craft a treatment plan tailored to your needs. We mean that literally: We may choose treatment options based on your DNA, or target specific traits in your cancer cells.

U.S. News & World Report has repeatedly named the Knight one of the nation’s top cancer centers. Our doctors bring you the skills and technology to tackle the most complex cancers. You’ll also find hundreds of clinical trials, offering a chance to try promising new therapies.

We offer many support services, including:

  • Nurses to guide you through care.
  • Dietitians to support nutrition.
  • Palliative specialists to ease pain and anxiety.
  • Social workers for advocacy, resources and compassion.
  • A guest house for patients and families who live outside the Portland area.
  • Patient education, support groups, acupuncture, yoga and more.

See services for patients and families

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For health care professionals

We will help you give your patient the best cancer care. We welcome your patient referral for expert treatment or a clinical trial. We also invite you to confer with our specialists and to deepen your knowledge through continuing education.

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For researchers

Dr. Brian Druker, director of the Knight Cancer Institute, helped usher in the era of targeted therapy through his groundbreaking work on Gleevec. Today, the Knight has hundreds of scientists studying everything from early detection to the most advanced cell therapies.

  • The National Cancer Institute recognizes the Knight as a Comprehensive Cancer Center, its highest distinction for research excellence and patient care.
  • Our Cancer Early Detection Advanced Research Center (CEDAR) is the world’s leading effort to find cancer early, when it’s most treatable.
  • We’re running studies to see if a simple blood test can find cancers earlier.
  • Our SMMART trials aim to outwit cancer by targeting several pathways at once.
  • Our 320,000-square-foot Knight Cancer Research Building is designed to promote teamwork and spur collaboration.
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For the community

The Knight Cancer Institute offers programs that serve all 36 Oregon counties. They include:

  • Grants to support community-level cancer projects.
  • Programs to help scientists connect with community members.
  • Collaborations with hospitals to extend care to more of the Northwest.
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What makes us different

Find out how the Knight Cancer Institute brings together teams of specialists and the latest therapies for each patient.

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Our story

Learn about the breakthroughs and milestones that have turned the Knight Cancer Institute into a top-ranked center for care and research.

Dr. Brian Druker

Meet Dr. Brian Druker

Learn how Brian Druker, M.D., opened the door to a revolution in cancer medicine.

Dr. Sadik Esener

Leaders

Meet the doctors, scientists and other leaders guiding the Knight Cancer Institute.

A U.S. News & World Report Best Hospitals badge for Cancer care for the fiscal year of 2022-23.

Honors and affiliations

Read about the Knight’s marks of excellence, and about our collaborations with some of the nation’s top cancer organizations.

Knight news

Blog: Learn about the latest findings on our Cancer Translated blog.

News: Read about research breakthroughs, patient care and other topics on our OHSU News site.