COVID-19 (Novel Coronavirus)

OHSU has declared modified operations as of March 23rd, 2020, to help slow the spread of the virus that causes COVID-19 (Novel Coronavirus).  During this period, most Shared Resource Cores will not be processing or accepting samples for research studies or starting new projects. Exceptions will be rare, for example, for projects approved by the OHSU COVID-19 Research Task Force.

Many Cores’ staff members remain available for discussions, data analysis, manuscript preparation, and other activities that can be done remotely. We will continue to update individual core websites for information specific to each core. Please see individual websites, or contact core personnel for specific core related questions.

Helpful links:

OHSU Core service centers

Core Service Profile Overview Sheet

Advanced Computing Center - Consulting, research storage, application hosting, support for research computing systems.
Service Profile

Advanced Imaging Research Center - Novel Magnetic Resonance Imaging (MRI), data analysis, and user education. 

Advanced Light Microscopy Core - Access to and education on the use of advanced instrumentation for fluorescence microscopy in cells, tissues, and animals.
Service Profile

Bioanalytical/Pharmacokinetics - Support and consultation for the analysis of small molecules using state-of-the-art LC-MS/MS, GC/MS, or HPLC instrumentation. 
Service Profile

Bioinformatics - Experimental Design and Analysis support for high dimensional data 
(e.g., RNA-seq, DNA-seq, ChIP-seq, CyTOF, etc). Data stewardship, management, and dissemination support.

Bioinformatics & Biostatistics Core (BBC) at ONPRC - Supports all types of biostatistics and primarily DNA/RNA-sequencing-related bioinformatics. Provides analysis, study design, advising, and grant support.
Service Profile

BioLibrary - Fresh, frozen, OCT, FFPE tissues and blood derivatives; prospective whole blood collection; PI-driven consenting of patients; digital slide imaging.

Biostatistics & Design Program - Statistical guidance, analysis, and study design for proposal development, grant submissions and research projects including: data management, statistical programming, report preparation, and assistance with manuscripts.
Service Profile

Clinical and Translational Research Core Services - Study Coordination, Education, and Career development, Biostatistics, Biomedical Informatics, Investigator Support and Integration, Community and Practice Research Funding.

Elemental Analysis Core - ICP-MS: determination of elemental content, sample preparation, data analysis, and consolation.
Service Profile

Epigenetics Consortium - Sample preparation and bioinformatics analysis for epigenetics assays (e.g. Methyl-seq, Chip-seq, ATAC-seq)

Flow Cytometry - Cell sorting and analytical flow cytometry, data analysis, consultation, and user education and training.
Service Profile

Histopathology - Specimen imbedding, sectioning, staining, and immunohistochemistry. 
Service Profile

Integrated Genomics Laboratory - Technologies, services, and expertise for genome-wide and targeted RNA and DNA analysis.

MedEdNet Survey Services – Support and consultation for scannable paper surveys and web based surveys. Services include survey set up, administration, and data processing.

Medicinal Chemistry Core - Investigates the interactions between small molecules and biological systems by providing medicinal chemistry and chemical biology expertise and organic synthesis support.
Service Profile

Multiscale Microscopy Core - State-of-the-art electron and light microscopy facility providing imaging services, access and technical support to OHSU and external customers.
Service Profile

Proteomics - Mass spectrometric services to allow protein identification, detection of post-translational modifications, and profiling of changes in relative protein abundance.
Service Profile

Small Animal Research Imaging Core - MicroPET-SPECT/CT, high frequency ultrasound, and biophotonics imaging services to evaluate anatomy, tissue function, cellular and molecular phenotype, blood/fluid flow, and metabolism.

Transgenic Mouse Models - Development of genetically engineered mouse models, cryopreservation, and other services.
Service Profile

Virology - Production of viral vectors, virus stocks and antigens. Viral diagnostics for virus quantification and serology. User consultation and education.

USR Core Pilot Awards - FY2020

December 2019 update: 
Thank you to everyone who submitted an application for a FY2020 USR Core Pilot Award!  We received over 30 applications for funding to explore exciting research applications involving University Shared Resources cores.   These applications were reviewed, and awardees were informed on December 20th.  If you did not receive a decision response on December 20th, please contact Andrew Chitty and Aaron Larson.

Single cell analysis resources at OHSU

Advancements in technology now permit the analysis of samples at the single cell level.  The University Shared Resources and others at OHSU are beginning to utilize these exciting advances.

  • Massively Parallel Sequencing Shared Resource
  • Flow Cytometry
    • In support of single cell studies, the Flow Cytometry Shared Resource has the capability of sorting discrete populations of cells as well as individual cells into tubes and/or plates. These cell sorts can be performed on the basis of up to 18 fluorescent parameters.
    • Please contact Philip Streeter in the Flow Cytometry Shared Resource
  • Histopathology
  • Mass Spectrometry
    • Stay tuned for future single cell proteomics and single particle elemental analysis

If you have questions, would like to request additional services, or see information missing from this page, please contact Aaron Larson in the University Shared Resources office.

Research News

More core resources

University Shared Resource Core boilerplates

If you are planning to include an OHSU Shared Resource in a grant or other project proposal, please contact the Shared Resource/Core director for guidance with assay/service selection, study design, cost estimates, and letters of support.

To request a USR Core boilerplate, please complete and submit the Boilerplate Request Form.

School of Medicine Faculty Innovation Fund pilot program continues

The School of Medicine encourages innovative and diverse investigations by offering up to $5000 for core spending. 
More info and application guidelines

Acknowledgement and authorship policies

Acknowledgement policy

The use of data generated in a core facility in a grant application, progress report or publication contains the implicit understanding that the PI or authors will acknowledge the use of the core facility.  Since many of our facilities are supported by federal agencies, such acknowledgments are essential for obtaining continuing support. 

Authorship policy

If core personnel provide significant intellectual input to the results submitted for publication, then it is reasonable and appropriate to include them as co-authors.  Since circumstances vary widely, each case should be considered individually, and the core should be consulted for review prior to publishing.