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Matthew Drake, M.D.

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  • Assistant professor of medicine
  • Associate Professor of Medicine, Division of Pulmonary and Critical Care Medicine, School of Medicine


  • Pulmonary Medicine

Special focus

  • Asthma
  • Critical Care
  • Pulmonary

Locations and contact

I see patients at

About me

Dr. Drake’s research focuses on airway neurobiology and innate immunity in asthma, with a particular focus on Toll-like Receptors. Dr. Drake has shown that Toll-like Receptor 7 agonists act as a novel class of bronchodilators via the induction of nitric oxide. He has also shown that airway parasympathetic nerves express Toll-like Receptor 7. His current work focuses on the significance and mechanisms of Toll-like Receptor signaling on airway nerves in models of non-allergic and allergic airway inflammation.

Drake MG, Scott GD, Proskocil BJ, Fryer AD, Jacoby DB, Kaufman EH. Toll-like receptor 7 rapidly relaxes human airways. Am J Respir Crit Care Med 2013;188(6):664-72. PMID: 23924358.

Drake MG, Evans SE, Dickey BF, Fryer AD, Jacoby DB. TLR2/6 and TLR9 agonists suppress viral replication but not airway hyperreactivity in guinea pigs. Am J Respir Cell Mol Biol 2013;48(6):790-6. PMID: 23449736.

Drake MG, Kaufman EH, Fryer AD, Jacoby DB. The therapeutic potential of toll-like receptor 7 stimulation in asthma. Inflamm Allergy Drug Targets 2012;11(6):484-91. PMID: 23078048.

Drake MG, Witzmann FA, Hyde J, Witten ML. JP-8 jet fuel exposure alters protein expression in the lung. Toxicology 2003;191(2-3):199-210. PMID: 12965123.

Education and training

    • M.D., 2007, University of Arizona College of Medicine
  • Residency

    • Internal medicine, Oregon Health and Science University, 2007 - 2010
  • Fellowship

    • Pulmonary and critical care medicine, Oregon Health and Science University, 2010 - 2014
  • Certifications

    • Internal medicine

Memberships and associations:

  • American Thoracic Society
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