Autopsy services

Working with the OHSU Hospital Decedent Affairs Office, we provide autopsies on patients who have died while admitted in the OHSU hospital (greater than 24 hours after presentation).

Autopsies investigate cause of death, observe disease and the effects of treatment and educate physicians and medical staff. We also provide quality assurance data and support tissue banking and research. 

To request autopsy reports, contact Decedent Affairs at 503-494-8115.

Questions?

Call the Pathology Autopsy Services team at 503-494-8276.

OHSU Department of Pathology
Mail Code L113
3181 SW Sam Jackson Park Rd.
Portland, OR 97239

Fax: 503-494-2025

Bone and soft tissue pathology services

We offer in-house and consultative services for diagnosing soft tissue and bone neoplastic and non-neoplastic disease. Please include the complete clinical history and imaging results with all requests. Surgical pathology interpretation cases we offer:

• Broad IHC menu, including STAT6, MDM2, CDK4, PanTRK, ALK, MUC4 and Rb
• FISH: MDM2, EWSR1, FUS, ALK, FOXO1, NTRK1-3, ROS1, RET and more (Cancer FISH panel)
• NGS: targeted tumor analysis (mutation and fusion detection) and whole exome

Request bone and soft tissue services

Submit the Laboratory Testing Requisition Form. Include the complete clinical history and imaging results.

Contact us

If you have questions, please contact Surgical Pathology at 503-494-6776.

OHSU Department of Pathology
Mail Code L471
3181 SW Sam Jackson Park Rd.
Portland, OR 97239

Fax: 503-494-6787

Our faculty

Breast pathology services

We offer comprehensive breast pathology services, including grossing, sentinel lymph node protocol, diagnostic interpretation and consultation for challenging cases. Biomarker and molecular testing is available through the Immunohistochemistry Lab and the Knight Diagnostic Laboratories. Services include: 

• Grossing specimens and sentinel lymph node protocol
• Diagnostic comprehensive interpretations
• Consultation for challenging breast pathology cases
• Breast biomarkers by IHC: ER, PR, Ki-67 and PATHWAY anti-HER-2/neu (4B5)
• KDL: HER2 FISH

Request breast pathology services

Submit the Laboratory Testing Requisition Form. Include the complete clinical history and imaging results.

Contact us

If you have questions, please contact Surgical Pathology at 503-494-6776.

OHSU Department of Pathology
Mail Code L471
3181 SW Sam Jackson Park Rd.
Portland, OR 97239 

Fax: 503-494-6787

Our faculty

Cytopathology services

We process approximately 12,000 gynecologic specimens, 5,000 non-gynecologic specimens and 1,000 fine needle aspiration biopsies each year. Our diagnostic image-guided FNA cytopathology services include:

• Ultrasound-guided (U/Sg) thyroid and lymph node FNA
• Endoscopic ultrasound-guided (EUSg) FNA
• Endobronchial ultrasound-guided (EBUSg) FNA
• CT-guided (CTg) FNA and navigational bronchoscopy
• FNA of palpable lesions, with emphasis on head and neck neoplasms

Request cytopathology services 

Submit the Laboratory Testing Requisition Form. Include the complete clinical history and imaging results.

Contact us

If you have questions, please contact Surgical Pathology at 503-494-6776.

OHSU Department of Pathology
Mail Code L471
3181 SW Sam Jackson Park Rd.
Portland, OR 97239

Fax: 503-494-6787

Our faculty

Gastrointestinal, liver and pancreas pathology services

We offer professional interpretation of complex GI, liver and pancreatobiliary cases. Our team uses a comprehensive suite of molecular testing through the Knight Diagnostic Laboratories to perform services, including:

• Interpretation of complex GI, liver and pancreatobiliary cases
• HER2 testing by IHC and FISH
• Mismatch repair (MMR) IHC: MLH1, MSH2, MSH6 PMS2
• MSI PCR, MLH1 hypermethylation, BRAF testing
• GeneTrails® Comprehensive Solid Tumor Panel (225 genes)
• GeneTrails® GIST Genotyping Panel (23 genes)
• Inherited Colorectal Cancer Sequencing: Lynch (MLH1, MSH2, MSH6, PMS2), FAP (APC)

Request GI, liver and pancreatobiliary services 

Submit the Laboratory Testing Requisition Form. Include the complete clinical history and imaging results.

Contact us

If you have questions, please contact Surgical Pathology at 503-494-6776.

OHSU Department of Pathology 
Mail Code L471
3181 SW Sam Jackson Park Rd.
Portland, OR 97239

Fax: 503-494-6787

Our faculty

Genitourinary pathology services

We offer comprehensive GU pathology services, including grossing, intraoperative consultation, diagnostic interpretation and consultation for challenging cases. Services include: 

• Grossing specimens
• Intraoperative consultations
• Diagnostic comprehensive interpretations
• Consultation for challenging GU pathology cases
• Immunohistochemistry
• KDL: Inherited Cancer Panel

Request genitourinary pathology services 

Submit the Laboratory Testing Requisition Form. Include the complete clinical history and imaging results.

Contact us

If you have questions, please contact Surgical Pathology at 503-494-6776.

OHSU Department of Pathology
Mail Code L471
3181 SW Sam Jackson Park Rd.
Portland, OR 97239

Fax: 503-494-6787

Our faculty

Gynecologic pathology services

We offer complete gynecologic pathology services including grossing, intraoperative consultations, diagnostic interpretation and consultation for challenging cases. Mismatch repair testing and molecular profiling are integrated into the diagnostic workup. Services include: 

• Grossing specimens
• Intraoperative consultations
• Diagnostic comprehensive interpretations
• Consultation for challenging gynecologic cases
• Mismatch repair (MMR) by immunohistochemistry
• KDL: PCR for Microsatellite Instability (MSI), MLH1 Promoter Hypermethylation and Inherited Cancer Panel

Request gynecologic pathology services 

Submit the Laboratory Testing Requisition Form. Include the complete clinical history and imaging results.

Contact us

If you have questions, please contact Surgical Pathology at 503-494-6776.

OHSU Department of Pathology 
Mail Code L471
3181 SW Sam Jackson Park Rd.
Portland, OR 97239

Fax: 503-494-6787

Our faculty

Head, neck and endocrine pathology services

We offer subspecialty pathology services for head and neck and endocrine specimens, including grossing, intraoperative consultations, diagnostic interpretation and consultation for challenging endocrine cases. Services include:

• Grossing specimens; intraoperative consultations
• Diagnostic comprehensive interpretations; consultation for challenging endocrine pathology cases
• Immunohistochemistry
• KDL: Inherited Cancer Panel

Request head, neck and endocrine pathology services 

Submit the Laboratory Testing Requisition Form. Include the complete clinical history and imaging results.

Contact us

If you have questions, please contact Surgical Pathology at 503-494-6776.

OHSU Department of Pathology
Mail Code L471
3181 SW Sam Jackson Park Rd.
Portland, OR 97239

Fax: 503-494-6787

Our faculty

Heart and lung pathology services

We offer complete cardiothoracic pathology services including grossing, intraoperative consultations, diagnostic interpretation and consultation for challenging lung and heart pathology cases. Services include:

• Grossing specimens
• Intraoperative consultations
• Diagnostic comprehensive interpretations
• Consultation for challenging lung and heart cases
• Immunohistochemistry and immunofluorescence
• KDL: NSCLC FISH Panel (ALK, RET, ROS1, MET)
• Lung Cancer Panel (EGFR, ALK, ROS1); ALK FISH
• GeneTrails NSCLC Genotyping Panel

Request heart and lung pathology services 

Submit the Laboratory Testing Requisition Form. Include the complete clinical history and imaging results.

Contact us

If you have questions, please contact Surgical Pathology at 503-494-6776.

OHSU Department of Pathology
Mail Code L471
3181 SW Sam Jackson Park Rd.
Portland, OR 97239

Fax: 503-494-6787

Our faculty

Hematopathology services

Our seven hematopathologists provide complete evaluation of lymph node, bone marrow and other tissue specimens for lymphomas, leukemias and other hematologic disorders. We offer:

• Comprehensive evaluation of blood, bone marrow, lymph nodes, spleen and tissue specimens for hematologic disorders
• Hematopathology consultation services for malignant and benign hematopoietic diseases
• Flow cytometric immunophenotyping, including leukemia/lymphoma immunophenotyping, B-ALL MRD assessment, CD34+ stem cell quantitation, lymphocyte subset analysis, ALPS evaluation, PNH screening and CAR-T cell quantitation
• Extensive immunohistochemistry and in situ hybridization testing
• Molecular genetic pathology interpretation, including NGS and clonality studies
• Integrated molecular, cytogenetic, flow cytometric and morphologic assessment
• Hemoglobinopathy and monoclonal protein studies

Request hematopathology services 

Submit the Laboratory Testing Requisition Form. Include the complete clinical history and imaging results.

Contact us

If you have questions, please contact Surgical Pathology at 503-494-6776.

For fixatives and technical information, all the Immunology Lab at 503-494-2302.

OHSU Department of Pathology
Mail Code L471
3181 SW Sam Jackson Park Rd.
Portland, OR 97239

Fax: 503-494-6787

Our faculty

Immunohistochemistry services

The Immunohistochemistry (IHC) Lab offers nearly 200 immunohistochemical tests for formalin-fixed, paraffin-embedded tissue, performed on Ventana automated immunostainers. The lab also provides a dystrophy panel on frozen muscle tissue and immunofluorescence staining for renal native and transplant cases. You will find:

• Nearly 200 IHC tests for FFPE tissue on Ventana automated immunostainers
• In situ hybridization
• Dystrophy panel on frozen muscle tissue
• Immunofluorescence for renal native and transplant cases

Request immunohistochemistry services 

Submit the Laboratory Testing Requisition Form. Include the complete clinical history and imaging results.

Contact us

If you have questions, please call:

• Surgical Pathology at 503-494-6776
• IHC Lab at 503-494-5755

OHSU Department of Pathology
Mail Code L471
3181 SW Sam Jackson Park Rd.
Portland, OR 97239

Fax: 503-494-6787

Our faculty

Lab Services

Our Lab Services team offers a full range of laboratory and pathology services to OHSU clinicians and external healthcare professionals. We are CAP-accredited (CAP# 2442601, CLIA# 38D0676694). Services include specialized tests and referrals for unusual laboratory procedures.

Lab Services resources

• Test directory listing specifications for all tests
• Forms and requisitions
• Specimen collection information

Request lab services

Contact Lab Services to submit a request. Send specimens to OHSU Laboratory Services.

• 503-494-7383 or 1-888-375-4636 
• ohsulabs@ohsu.edu

OHSU Laboratory Services
Mail Code HRC9
3181 SW Sam Jackson Park Rd.
Portland, OR 97239

Molecular genetic pathology services

As part of OHSU's Knight Cancer Institute, the Knight Diagnostic Laboratories offers a variety of molecular pathology services.

Formed in 2011 through a merger of four pathology and genetics laboratories, the KDL provides molecular and genetic tests and accurate diagnosis. Its services support personalized care for cancer and rare genetic disorders. You will find:

• Comprehensive tumor profiling, including NGS panels 
• Somatic mutation analysis and gene fusion detection
• Germline and inherited cancer variant testing
• FISH studies, MGMT promoter methylation, genome-wide copy number profiling
• Testing for oncology and rare genetic disorders

Request molecular genetic pathology

Contact KDL Client Services for information about how to order services.

• 855-535-1522             
• Fax: 855-535-1329
• KDLClientServices@ohsu.edu

Our faculty

Neuropathology services

We provide diagnostic services and research for all aspects of neuropathology, including surgical/oncologic neuropathology and neuromuscular pathology.

Surgical and oncological neuropathology services

We offer in-house and consultative services for adult and pediatric neurosurgical specimens. Our molecular testing through KDL includes MGMT promoter methylation, targeted/NGS DNA sequencing, genome-wide copy number profiling, gene fusion detection (FISH or RNA) and whole exome sequencing. We are also:

• Expanding IHC panel including IDH1 R132H, H3 K27M, Pit-1, T-Pit, SF-1, ATRX, p53
• Participating in weekly adult and pediatric multidisciplinary tumor board meetings

Neuromuscular pathology services

We accept specimens from across the Pacific Northwest. Tests and services include:

• Skeletal muscle and peripheral nerve specimens from adult and pediatric patients
• Histochemical stains, IHC and electron microscopy as appropriate
• Common diagnoses of inflammatory myopathies, dystrophies, metabolic myopathies, drug-induced myopathy, motor neuron diseases and vasculitis

Request neuropathology services

Submit the Laboratory Testing Requisition Form. Include the complete clinical history and imaging results.

Contact us

If you have questions, please contact Surgical Pathology at 503-494-6776.

OHSU Department of Pathology 
Mail Code L471
3181 SW Sam Jackson Park Rd.
Portland, OR 97239 

Fax: 503-494-6787

Our faculty

Pediatric pathology services

We provide in-house and consultative services for diagnosing pediatric neoplasia and non-neoplastic disease, serving OHSU Doernbecher Children's Hospital and referring providers. Services include:

• Placental and perinatal evaluation
• KDL Requisition Perinatal FISH and sequencing for aneuploidy, deletion and others.
• Constitutional cytogenetics 
• Diagnosis of pediatric neoplastic and non-neoplastic disease
• Pediatric GI biopsies including Hirschsprung disease (calretinin and choline transporter IHC)
• Pediatric transplant biopsies
• Pediatric vascular abnormalities
• Pediatric Molecular interpretation
• Active participation in weekly adult and pediatric multi-disciplinary tumor board meetings to help guide clinical decision-making 
• Broad immunohistochemistry lab menu, including: CD1a, Myogenin, Phox2B, PanTRK, SDHB, FH, ALK and others.
• Cancer FISH for EWSR1, FUS, ALK, FOXO1, NTRK1-3, ROS1, and RET and others.

Microarray

• Neuroblastoma (MYC-N etc) 
• Wilm's Tumor (copy number changes, LOH 1p, 16q, 1q etc)
• Perinatal testing

Next generation sequencing panels

• GeneTrails® Solid Tumor Fusion Gene Panel
• GeneTrails® Solid Tumor Comprehensive Solid Tumor Panel (225 Genes)
• GeneTrails® Hematologic Malignancies Panel (220 Genes)
• GeneTrails® Inherited Cancer Panel
• Hematological Malignancies
• Cancer Cytogenetics and FISH

Request pediatric pathology services

Submit the Laboratory Testing Requisition Form. Include the complete clinical history and imaging results.

Contact us

If you have questions, please contact Surgical Pathology at 503-494-6776.

OHSU Department of Pathology
Mail Code L471
3181 SW Sam Jackson Park Rd.
Portland, OR 97239

Fax: 503-494-6787

Our faculty

Renal pathology services

OHSU has offered comprehensive renal pathology services locally and to communities in Oregon and Southwest Washington since the 1970s. Board-certified pathologists with formal training in nephrology and immunopathology provide timely preliminary information and progress reports on current cases. 

Services we offer

We provide a full complement of renal pathology services, unique among labs in Oregon, including:

• Native and allograft kidney biopsies 
• Light microscopy, immunofluorescence microscopy and electron microscopy
• Electron microscopy. This is not required for allograft renal insufficiency evaluation, but recommended if the patient has hematuria, proteinuria, or other glomerular disease evidence
• Additional IHC and in-situ hybridization for infectious, infiltrative and hereditary renal diseases
• Outside consultation on blocks or slides from renal biopsies, nephrectomies and autopsy cases

Request renal pathology services

Submit the Laboratory Testing Requisition Form. Include the complete clinical history and imaging results. Before sending fresh tissue, contact Surgical Pathology at 503-494-6776.

Explore more:

• How we report results
• Recommended fixatives
• Service billing codes
• Pathology services FAQ

Contact us

If you have questions, please contact Surgical Pathology at 503-494-6776.

For fixatives and technical information, call the Immunohistochemistry (IHC) Lab at 503-494-5755.

OHSU Department of Pathology
Mail Code L471
3181 SW Sam Jackson Park Rd.
Portland, OR 97239 

Fax: 503-494-6787 (Attn: Surgical Pathology or IHC Lab)

Our faculty

How we report results

Preliminary findings are based on the light microscopy findings usually provided by phone to the referring nephrologist or pathologist. A written preliminary report (pending electron microscopy) is available on request. Written final reports are provided for all consultations. Contact us to arrange to have your reports automatically faxed to a secure (office) site after it is signed.

Recommended fixatives

Please contact us if you would like us to supply these fixatives.

For light microscopy (LM):

• 10% aqueous formaldehyde (formalin). This is readily available in most pathology laboratories. 
• Paraformaldehyde and Carnoy's fixative are also satisfactory.

For immunofluorescence (IF) microscopy:

• Michel's fixative (Modified Michel's Tissue Fixative from Wampole Laboratories, Cranbury, N.J.)

Electron microscopy (EM): 

• 2-3% glutaraldehyde
• Paraformaldehyde is also suitable

Service billing codes

We offer services with these CPT codes for evaluation of a renal biopsy. For technical pricing, please call 503-494-6775. For professional pricing, please call 503-494-6010.