Oncologist Dr. Lara Davis stands in front of a whiteboard in her lab.
Oncologist Dr. Lara Davis is an expert on sarcoma. In addition to treating patients, she also works in the lab investigating new therapies for this complex condition.

The OHSU Knight Cancer Institute provides the region’s highest level of expertise and technology for treating sarcoma. We offer:

  • Team-based care, with a wide range of specialists who work together.
  • Clinical trials that provide access to promising new treatments.
  • Expert surgical skill to preserve limbs and to give you the best outcome possible.
  • Intraoperative radiation therapy to knock out cancer cells during surgery.
  • 3D printing to replace bone removed in surgery.
  • Advanced MRI scanning that gives us crucial insights into finding the best treatment.
  • National renown in treating patients with GIST, a a rare type of sarcoma.
  • A full range of support services for you and your family.

Our expertise

Our sarcoma team is the most experienced in Oregon and among the most experienced on the West Coast.

  • We treat many hundreds of sarcoma patients every year.
  • We use the most advanced surgical techniques.
  • We’re experts in biopsies that require exceptional precision.
  • We’re consistently ranked among the nation’s top cancer hospitals by U.S. News & World Report.
  • We're leading national trials of new ways to treat sarcoma and have authored dozens of articles about it.

Top minds together

Our surgeons, oncologists, nurses and others work together as a team to coordinate your care.

Nurse navigator: Your nurse navigator can often arrange multiple appointments on one day for your convenience. The team coordinates tests and treatments.

Tumor board meetings: Providers meet each week to go over cases together one by one. They look at scans and test results, then develop treatment recommendations. They take care to consider every option and clinical trial for the best treatment plan possible.

Collaboration: Providers meet face to face to discuss the care of each patient.

Convenient locations: You can receive all your care at our main South Waterfront and Marquam Hill campuses, which are connected by a short ride on the Portland Aerial Tram.

Dr. Christopher Ryan is a medical oncologist who specializes in treating sarcomas.
Dr. Christopher Ryan is a medical oncologist who specializes in treating sarcomas.

Advanced technology

MRI: We’re using state-of-the-art MRI technology to gather specific data about each tumor. This includes how it’s responding to treatments and how it might respond to chemotherapy or targeted therapy.

Radiation: We use advanced technology, such as the Mobetron linear accelerator, to beam a powerful dose of radiation directly onto your tumor during surgery. (This technique is also known as intraoperative radiation therapy or IORT.) We carefully choose the radiation therapy that will be most effective for your tumor and condition.

Bone replacement: We offer you every reconstruction option. When bone is removed to treat sarcoma, we can sometimes replace it with bone from another part of the body. Other times, we use advanced joint replacement. In some cases, we can even replace bone with custom 3D-printed implants.

Research and innovation

The Knight Cancer Institute is the only cancer center between Seattle and Sacramento with the National Cancer Institute’s highest designation for research excellence. Our work includes:

Sarcoma lab: Our Sarcoma Lab is dedicated to finding new ways to treat aggressive sarcoma in children, teens and adults. It is one of the projects led by the Center for Experimental Therapeutics.

Clinical trials: We’re testing new medications and ways to diagnose sarcoma. Learn more about our clinical trials.

MRI research: Our advanced MRI technology, in addition to helping us improve patient care, is helping us better understand sarcoma and effective treatment. Our promising work is being funded by the National Cancer Institute.

Early detection: The Knight Cancer Institute is undertaking a major effort to detect cancers earlier, when they’re most curable. The Cancer Early Detection Advanced Research Center, or CEDAR, is bringing together some of the best minds in the world.

Published work: OHSU researchers have published dozens of peer-reviewed papers on sarcoma findings in medical journals.

Survivorship registry: We collect information from sarcoma survivors who volunteer to participate in our Sarcoma Survivorship Registry. Our database is helping us better understand how treatments affect patients.

For patients

Call 503-494-7999 to:

  • Request an appointment
  • Seek a second opinion
  • Ask questions


Parking is free for patients and their visitors.

Center for Health & Healing Building 2
3485 S. Bond Ave.
Portland, OR 97239
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Stay informed

Blog: Learn about the latest findings on our Cancer Translated blog.

News: Read about research breakthroughs, patient care and many other topics on our OHSU News site.