Doernbecher Children's Hospital

Lancioni Lab Members

Michelle Underwood, Senior Research Assistant

Michelle received her BS degree in Biology with a minor in Genetics and Cell Biology from Washington State University in 2015. She became interested in immunology and infectious diseases during her time as a laboratory assistant in the immunodiagnostics department of the Washington Animal Disease Diagnostic Laboratory. She also gained experience in microbiology through her work with the Agriculture Research Service of the USDA.

Michelle worked as a laboratory technician at Labrix Clinical Services, Inc. before joining Dr. Lancioni's laboratory at OHSU in June 2016. In addition to handling the general laboratory operations, Michelle works for Dr. Lanioni's project involving immune dysregulation in people living with HIV and opioid-use disorder, and the effect that opioid abuse treatment has on HIV pathogenesis and immune regulation. She also works with Dr. Lancioni to study the ability of neonatal CD4+ T cells to directly respond to PAMPs via Toll-like receptor 2.

Michelle spends most of her free time outdoors, especially hiking. She also enjoys traveling and spending time with friends and family.

Luke Uebelhoer, PhD, Senior Research Associate

Dr. Uebelhoer is an immunologist and molecular virologist by training, with a particular focus in the host-pathogen interface. He received his Ph.D. from Emory University in 2011, where he studied mutational escape in CD8+ T cell epitopes and resulting viral fitness in hepatitis C virus (HCV). After this training, he pursued a postdoctoral fellowship at the Viral Special Pathogens Branch of the Centers for Disease Control and Prevention (CDC) in Atlanta, GA, developing systems to better understand the viral molecular genetics determinants essential for Marburg and Ebola virus replication in a natural reservoir host. During his time at the CDC, Dr. Uebelhoer performed field work in Uganda, where he became interested in immunological research involving lower and middle income (LMIC) populations.

In 2014, Dr. Uebelhoer and his family undertook a cross-country move to establish residence in Portland, OR. During a brief postdoctoral fellowship at the Vaccine and Gene Therapy Institute, he met Dr. Lancioni, who shared many of his interests including a passion for basic translational research. Together they built and manage a medical research team in Kampala, Uganda, which is funded by the Bill & Melinda Gates Foundation and whose primary focus is improving the care of undernourished acutely ill children to increase their quality of life and potential to thrive. Besides managing the day-to-day activities of this team, Dr. Uebelhoer is responsible for the immunological research component of this study.

In his free time, Dr. Uebelhoer enjoys spending time with "the girls": his wife, two young daughters, and Pepper, the new family puppy. When he is not in the lab or relaxing with his family, he can be found bouldering or skiing in the nearby mountains.