Pediatric Grand Rounds

Pediatric Grand Rounds are designed to discuss and evaluate evolving diagnostics and therapeutics as they relate to general and sub-specialty pediatrics, and describe community and academic resources relevant to contemporary pediatric practice. At the conclusion of this activity, participants will be able to discuss, assess, and manage care of children with either normal or complex care requirements.

Department of Pediatrics and School of Medicine faculty, community pediatricians, residents and students are welcome to attend this weekly lecture to learn about pediatric topics, research and challenging clinical cases. This activity is open to the public.

Time: Thursdays, 8-9 a.m.

How to attend: Livestream and WebEx- Please use this option if you would like to participate in the Q&A after. You may ask your question in the chat window. 

To receive CME credit: If you are not on our mailing list and would like CME credit for a session you attend via WebEx or livestream, please email: norgrenb@ohsu.edu

*Due to COVID-19 restrictions Pediatric Grand Rounds will be held via WebEx and live-stream and recording until further notice. 

May 13, 2021 | Fellowship Lecture

Molecularly Targeted Treatments in Spindle Cell Rhabdomyosarcoma 

Presented by Florence Choo, M.D., Pediatric Hematology Oncology Fellow, Department of Pediatrics

Learning Objectives: 

  • Review the background of spindle cell rhabdomyosarcoma (ssRMS) and need for developing new treatments
  • Discuss efficacy of mTOR and MAPK targeted treatments in a patient derived ssRMS cell model

New Hematology-Oncology Therapies

Presented by Patrick DeMartino, M.D., Fellow, Division of Pediatric Hematology Oncology

Learning Objectives: 

  • Explore what impacts the affordability of a therapy
  • Consider the budget impact of a gene therapy for sickle cell disease

Recognizing PARDS: A Mixed-Methods Implementation Study of the PALICC Consensus Recommendations Statements

Presented by Avi Kopstick, M.D., Fellow, Division of Pediatric Critical Care Medicine

Learning Objectives: 

  • Understand how providers in a tertiary PICU Implementation the latest pediatric acute respiratory distress (pARDS) guidelines
  • Suggest potential revisions to the definition of pARDS in order to improve recognition and adherence to best practices

Assessing Pediatric Resident Neonatal Delivery Room Management Using an Entrustable Professional Activity (EPA) Tool

Presented by Catherine Caruso, D.O., Neonatal-Perinatal Medicine Fellow,  Department of Pediatrics

Learning Objectives: 

  • Define entrustable professional activities (EPA)
  • Consider how you might apply an EPA framework to assessing trainee competency in your field
May 20, 2021 | Wert Lecture

Congenital Athymia: From Diagnosis to Management and Treatment

Presented by M. Louise Market, M.D., Ph.D., Professor of Pediatrics and Immunology

Learning Objectives: 

  • How to diagnose patients with congenital athymia
  • How to manage patients with congenital athymia prior to cultured thymus tissue implantation
  • Results of Cultured thymus tissue implantation
May 27, 2021| Braner Lecture

Presented by Charles Branas

June 3, 2021 | Cazden Lecture
June 10, 2021 | Jeff Miller Lecture and Award

Presented by Erik Brodt and Caitlin Donald

June 17, 2021

Beyond "Born in the Wrong Body": Challenging our Biases to Provide Inclusive Gender Affirming Care 

Presented by Danielle Moyer, Ph.D., Assistant Professor of Pediatric Psychology, Jess Guerriero, M.A., M.S.W., Intake and Referral Specialist, Transgender Health Program, and Kara Connelly, M.D., Associate Professor of Pediatric Endocrinology 

Learning Objectives: 

  • Define the care needs of Nonbinary youth
  • List various pathways for affirming gender
  • Define shared decision making and apply to case review
  • Identify the impact of law and policy in affirming care
June 24, 2021 | Meechan Award

Presented by Monika Davare

September 10, 2020

Acute Flaccid Myelitis (AFM): This Generation's Polio?

Presented by Dawn Nolt, M.D., M.P.H., Professor, Pediatric Infectious Diseases, OHSU

Learning Objectives

  • Understand the US national perspective on AFM
  • Recognize this disease
  • Conduct the appropriate diagnostic evaluation
  • Realize the impact of COVID-19 on incidence of AFM
September 17, 2020

What's in a Smile? Pediatric Facial Paresi and (re) Animation

Presented by Lori K. Howell, M.D., F.A.A.P., Assistant Professor, Division of Plastic and Reconstructive Surgery, Interim Medical Director Cleft and Craniofacial, Associate Residency Program Director, Doernbecher Children's Hospital, OHSU

Learning Objectives

  • Recognize common congenital and acquired etiologies of facial paresis in children. 
  • Interpret importance of timing of injury and possible surgical (re)animation options. 
  • Assemble knowledge of one-stage and two-stage free functional muscle transfer for pediatric facial (re) animation. 
September 24, 2020

Infection, Inflammation & Mental Health- Mapping the Intersections

Presented by Jennifer Frankovich, M.D., M.S., Clinical Associate Professor of Pediatrics Rheumatology, Director of the Stanford PANS Research Program, Co-Director of Stanford Children's Health Immune Behavioral Health Clinic 

Learning Objectives

  • Give examples of a well-defined inflammatory disorders that can present with psychiatric symptoms. 
  • What is the general approach to treating inflammation based on neuropsychiatric disorders like Sydenham's Chorea, Lupus, PANS/PANDAS, etc. 
October 1, 2020

Reversing Dysbiosis of Inflammatory Bowel Disease

Presented by Henry Lin , M.D., M.B.A., Associate Professor of Pediatrics and Anna K. Hunter, M.D., Assistant Professor of Pediatrics, Division of Pediatrics, Department of Pediatric Gastroenterology, Hepatology and Nutrition 

Learning Objectives:

  • Changing trends in epidemiology of IBD
  • Multifactorial etiology of IBD
  • What is current understanding of IBD related dysbiosis
  • Dietary interventions of IBD
October 8, 2020

Information Sharing in Pediatrics: Effects of the Final Rule of the 21st Century Cures Act

Presented by Ben Orwoll, M.D., M.S., Assistant Professor, Department of Pediatrics, Division of Critical Care, Department of Medical Informatics and Clinical Epidemiology 

Learning Objectives:

  • Participants will gain an understanding of what information blocking is, as defined by the CURES act, and key elements of how new regulations will affect how patients access their health data.
  • Understand some key considerations around ensuring the safety and necessary privacy of the health information of our most vulnerable populations.
October 15, 2020

Trajectories of Lung Function for Infants and Children: Setting a Course for Lifelong Lung Health

Presented by Brian  K. Jordan, M.D., Ph.D., Assistant Professor of Pediatrics, Division of Neonatology 

Learning Objectives: 

  • To recognize that infants have trajectories of lung function that are established very early in life
  • To appreciate that these early trajectories predict peak lung function in early adulthood
  • To understand that prematurity alters an infant's lung trajectory
October 23, 2020- Cindy Ferrell Lecture
October 29, 2020

What Happened to that EI Referral I Sent for my Patient? In Search of Solutions to Improving Referrals to Early Intervention

Presented by Ben Sanders, M.D.

Learning Objectives: 

  • Understand ways in which Early Intervention can be both effective and underused by children and families who may benefit the most. 
  • Describe ways in which the referral step in the entry pipeline plays a key role in access to Early Intervention and its associated inequities. 
  • Describe opportunities presented by information technology to reduce Early Intervention access barriers in the next decade. 
  • Think critically about evaluation methods of potential solutions to these access barriers. 
November 5, 2020

Threading the Needle- Use of Cross-Sector, Adverse Childhood Experiences Informed Data to Drive Meaningful Action in Oregon

Presented by Colleen Reuland, M.S., Director of the Oregon Pediatric Improvement Partnership, Instructor-Department of Pediatrics, Doernbecher Children's Hospital, OHSU

Learning Objectives: 

  • To provide an overview of the Oregon Pediatric Improvement Partnership and the work and approach we use to galvanize improvement efforts across the state. 
  • To share findings from the novel pediatric health complexity data for Oregon's publicly insured children, which leverages cross cross-sector, adverse childhood experiences informed indicators about medical and social complexity and what it means for front-line health care providers. 
  • To describe how the pediatric health complexity data is being used to galvanize meaningful action at the system, community and practice level. 
November 12, 2020

When "Advanced" Isn't : Early Developmental Milestone Acquisition as a Sign of Abnormal Development 

Presented by Daniel Crowder, M.D., Assistant Professor, Pediatrics, Neurodevelopmental Disabilities 

Learning Objectives: 

  • Identify major milestones in early childhood development. 
  • Recognize common out-of-sequence developmental milestones that suggest abnormal development. 
November 19, 2020

Opportunities for Prevention of Pediatric Chronic Pain: Psychosocial and Intergenerational Factors

Presented By Anna C. Wilson, Ph.D., Associate Professor, Institute on Development and Disability, Department of Pediatrics 

Learning Objectives: 

  • Gain knowledge of the cost and impact of pediatric chronic pain. 
  • Understand the importance of psychosocial and family factors in the development of pain problems, and how these might be targeted for prevention. 
December 3. 2020 | Cazden Lecture

A Motley Crew, Thinking Differently, Built the Fontan

Presented by Thomas J. Kulik, M.D., Senior Associate in Cardiology, Boston Children's Hospital, Associate Professor of Pediatrics, Harvard Medical School 

Learning Objectives:

  • Learn about some of the key developments in the evolution of pediatric cardiology and cardiac surgery
  • Appreciate the multiple ways that people have made important contributions to the field
December 10, 2020

Nanomedicine Therapies for Cystic Fibrosis (CF)

Presented by Kelvin MacDonald, M.D., Associate Professor, Pediatric Pulmonology  and Anindit Mukherjee

Learning Objectives: 

  • Review the "state of the art" with CF protein rescue therapies
  • Discuss the advantages to mRNA based gene therapy over DNA in restoring CFTR protein
  • Review the role of the Epithelial Sodium Channel as a target in CF
December 17, 2020

Pediatric Brain Tumors- Where We Are At in 2020

Presented by Matthew Miller, M.D., Assistant Professor, Pediatric Hematology and Oncology  

Learning Objectives: 

  • Appreciate the multidisciplinary care required to address the needs of the pediatric brain tumor population
  • Recognize recent advances in the treatment of pediatric brain tumor patients
January 7, 2021

Does Early or Preventative Treatment of Epilepsy Rescue Development?

Presented by Juuriaan M. Peters, M.D., Ph.D.,  Division of Epilepsy and Clinical Neurophysiology, Boston Children's Hospital, Assistant Professor of Neurology, Harvard Medical School 

Learning Objectives: 

  • To gain insight in the developmental impact of uncontrolled seizures
  • To recognize key aspects of an epileptic encephalopathy 
  • To appreciate an impending paradigm shift towards early and preventative treatment 
January 14, 2021

When the Plumbing is Fixed but the Tap Runs Dry: Mechanisms of Heart Failure in Congenital Heart Disease

Presented by Lars Grosse-Wortmann, M.D., FRCPSC, Division Head, Pediatric Cardiology, Department of Pediatrics, Professor of Pediatrics, OHSU 

Learning Objectives: 

  • To understand the pathophysiology of heart failure in patients with congenital hear disease
  • To learn how we can examine myocardial tissue non-invasively 
  • To hear about current and future therapies to lessen myocardial fibrosis 
January 21, 2021

Racism in Oregon's Health Care System: Experiences of Families of Black and Latino Children and Youth with Special Health Care Needs 

Presented by Alison Martin, Ph.D., Claudia Bisso-Fetzer, Ph.D., M.A., Central Oregon Community College, Sheryl Gallarde-Kim, MSc, Oregon Center for Children Youth with Special Health Needs, Charles Smith, M.S.W., Charles Smith & Associates

Learning Objectives: 

The Oregon Center for Children and Youth with Special Health Needs (OCCSYHN) collaborated with the Sickle Cell Anemia Foundation of Oregon and the Latino Community Association to conduct a study using  a participatory needs assessment approach. One of the key findings was that families of Black and Latino children and youth with special health care needs (CYSHCN) experience racism in health care settings.

  • Discuss these findings in relations to Jones' (2000, 2003) levels of racism framework
  • Apply learnings to two practice scenarios
January 28, 2021

The Respiratory Implications of Neuromuscular Disease: Identification, Management and Future Directions

Presented by Courtney Gushue, M.D., Assistant Professor of Pediatric Pulmonology 

Learning Objectives:

  • Identify patients who may have respiratory muscle weakness
  • Describe the ways in which neuromuscular disease can affect the respiratory system
  • Contrast the respiratory anatomy and physiology in this population to those unaffected by weakness
  • Understand the general pulmonary management principles applied to this population
  • Appreciate the evolving disease phenotypes with advances in care
  • Recognize when to consult with or refer to additional subspecialty teams
February 4, 2021

Technology and Type 1 Diabetes- Has the Brave New World Arrived?

Presented by Ines Guttmann-Bauman, M.D., M.C.R., Associate Professor of Pediatrics, Division of Pediatric Endocrinology 

Learning Objectives:

  • Discuss diabetes device technology and its impact on clinical outcomes in Type 1 diabetes
  • Discuss the impact of telemedicine and other digital health tools on healthcare delivery in Type 1 diabetes 
February 11, 2021- Lipman Lecture

Towards a New TB Vaccine Strategy for Infants, Children and Adolescents

Presented by Mark Hatherill, M.D., Professor and Director of the South African Tuberculosis Vaccine Initiative, University of Cape Town

Learning Objectives: 

  • Understand the rationale for pre- and post- exposure vaccination strategies against Mycobacterium tuberculosis
  • Understand the differences between candidate TB vaccines that may be suitable for use in infants, children and adolescents 
February 18, 2021

Why Aren't There More Black People in Oregon?

Presented by Antwon Chavis, M.D., Assistant Professor of Pediatrics

Learning Objectives: 

  • Review and explore Oregon history, detailing historical examples of Black exclusion and discrimination that have occurred since its founding
  • Create a connection between the historical timeline of racial identity and power, and present day socioeconomic health disparities and social inequity that still exist
  • Review community organizations that are working to eliminate racial discrimination and disparities to enhance the quality of life for Black Oregonians 
February 25, 2021

From Bedside to Bench (and back?) : Considerations in Measurement of ASD-Related Phenotypes

Somer L. Bishop, Ph.D., Associate Professor in Psychiatry, University of California San Francisco 

Learning Objectives: 

  • Understand challenges in differential diagnosis of ASD and other disorders associated with social impairment 
  • Identify different "types" of social-communication impairments and understand limitations of currently available measures of social functioning
  • Understand potential utility of developmental phenotypes for stratification within ASD and NDDs
March 4, 2021

Supported Decision- Making: Why it's Important to you and the People you Care for 

Presented by Sharon Lewis, B.F.A., Principal, Health Management Associates, formerly US Commissioner of the Administration on Intellectual and Developmental Disabilities 

Learning Objectives: 

  • Understanding the concept of Supported-Decision- Making a process to implement self-determination and informed choice
  • Learning how Supported Decision-Making is evolving as an alternative to guardianship
  • Reviewing practical applications and examples of Supported Decision-Making for people with disabilities and their families 
March 11, 2021

Recognizing and Treating Opsoclonus Myoclonus Ataxia Syndrome to Improve Outcomes....Without a Biomarker

Presented by Mark Gorman, M.D., Department of Neurology, Boston Children's Hospital

Learning Objectives: 

  • To learn clinical features which help differentiate opsoclonus myoclonus ataxia syndrome (OMAS) from acute cerebellar ataxia (ACA)
  • To be able to select the most sensitive tests to detect neuroblastoma in setting of OMAS
  • To be aware of current approaches to identifying an autoantibody biomarker in OMAS
  • To appreciate current treatment approaches and potential impact on outcomes in OMAS
March 18, 2021

The Use of SMART Technology for the Diagnosis and Treatment for Pediatric Cancer

Presented by Ramon Francisco Barajas Jr., M.D., Associate Professor, Department of Radiology, Neuroradiology Section, Advanced Imaging Research Center, Knight Cancer Research Institute, Translational Oncology Research Program and Dexing Zeng, Ph.D., Associate Professor, Department of Radiology, Director of Organic Chemistry, Center for Radiochemistry Research 

Learning Objectives: 

  • Describe the types and applications of commonly used medical radiation
  • Define the role imaging plays in cancer therapy
  • Describe the rational of Radiotheranostics
  • Discuss the current clinical applications and limitations of systemic radionuclide therapy
April 1, 2021

Does Disrupted Brain Maturation in Congenital Heart Disease Originate in the Fetus?

Presented by Stephen A. Back, M.D., Ph.D., Director of Pediatric Neuroscience Research, Clyde and Elda Munson Professor of Pediatrics 

Learning Objectives: 

  • Define the fetal origins of neurodevelopmental disabilities arising from congenital heart disease
  • Define the role of fetal hypoxemia in the diffuse disturbances in brain maturation associated with congenital heart disease
  • Review current potential therapies to reduce the impact of fetal hypoxemia on disrupted brain maturation in congenital heart disease 
April 8, 2021

Perinatal Mood and Anxiety Disorders: The Role of the Pediatrician 

Presented by Nicole Cirino, M.D., C.S.T., I.F., Reproductive Psychiatrist, Associate Professor, Dept. of Psychiatry and OB/GYN, Division Chief, Women's Mental Health and Wellness, Director, Perinatal Mental Health Program, Co-Director, Menopause and Sexual Medicine Program, Center for Women's Health, OHSU

Learning Objectives: 

  • Describe etiology, diagnosis and treatment of Perinatal Mood and Anxiety Disorders
  • Understand how to assess lactation safety and risk benefit ratio of psychotropic medication
  • List three ways a pediatrician may support the mother whom has been diagnosed with a PMAD
April 15, 2021 | Bilderback Lecture and Awards

Meeting the Moment: Achieving Optimal Health for All Children 

Presented by Sara Goza, M.D. 

Learning Objectives:

  • Inform the audience of current AAP organizational priorities
  • Communicate strategies to engage members in advocacy activities and initiatives
  • Discuss current legislative issues impacting pediatrics and child health
April 22, 2021

Restoring Healthy Sleep to Accelerate Recovery: Emerging Data from the Pediatric Critical Care and Neurotrauma Recovery Program 

Presented by Cydni N. Williams, M.D., M.C.R., OHSU, Associate Professor of Pediatrics, Division of Pediatric Critical Care, Director, Pediatric Critical Care and Neurotrauma Recovery Program 

Learning Objectives: 

  • Learn about the neurobiology of sleep in brain injury and repair
  • Learn about the impact of sleep disturbances on Post-Intensive Care Syndrome morbidities 
April 29, 2021

Navigating Care of Children and Adolescents with Differences in Sex Development: Doernbecher Sex Development Program

Presented by Hayley Baines, MD, MCR, Assistant Professor, Pediatric Endocrinology, Kara Connelly, MD, MCR, Associate Professor, Pediatric Endocrinology, Cori Feist, MS, CGC, Genetic Counselor, Brian Jordan, MD, PhD, Assistant Professor, Neonatology, Danielle Moyer, PhD, Assistant Professor, Pediatric Psychology, and Casey Seideman, MD, Assistant Professor, Urology 

Learning Objectives: 

  • Describe approach to differential diagnosis and initial evaluation of infants and children with atypical genitalia
  • Review shared decision making model for care of children with differences in sex development (DSD)
  • Differentiate key components of ethical and legal considerations impacting care of children and adolescents with DSDs
  • Identify who and how to contact the Doernbecher Sex Development Program team for care and consultation 
May 6, 2021| Perko Lecture

Adolescents and Young Adults Facing Illness and Loss;, Finding Meaning, Focusing on Hope

Presented by Barbara Jones, Ph.D., M.S.W., F.N.A.P., Associate Dean for Health Affairs  University Distinguished Teaching Professor and Josleen and Frances Lockhart Memorial Professor of Social Work Co-Director, Institute for Collaborative Health Research and Practice Steve Hicks School of Social Work ,Chair, Department of Health Social Work Associate Director of Social Sciences and Community Based Research, Livestrong Cancer Institutes  Professor of Oncology, Population Health, and Psychiatry and Behavioral Sciences Dell Medical School

Learning Objectives: 

  • Describe losses experienced by adolescents and young adults (AYA) facing illness
  • Review key psychosocial issues for adolescents and young adults
  • Understand the core competencies of interprofessional collaborative care
  • Identify ways to support AYAs, the families, and ourselves