Skye C. Mayo, M.D., M.P.H., F.A.C.S.

  • Associate Professor of Surgery, Division of Surgical Oncology, School of Medicine
  • Director of Hepatic Arterial Infusion for Advanced Liver Malignancies, OHSU Knight Cancer Institute, School of Medicine


  • M.D., 2006, Oregon Health & Science University School of Medicine
  • M.P.H., 2006, Oregon Health & Science University School of Public Health and Preventive Medicine
  • Internship:

    • General Surgery, The Johns Hopkins Hospital, 2006
  • Residency:

    • General Surgery, The Johns Hopkins Hospital, 2013
  • Fellowship:

    • Cancer Immunology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Medical Institutions, 2011
    • Complex General Surgical Oncology, Hepatopancreatobiliary Focus, Memorial Sloan-Kettering Cancer Center, 2013-15
  • Certifications:

    • American Board of Surgery, General Surgery, 2013
    • American Board of Surgery, Complex General Surgical Oncology, 2016

Memberships and associations

  • Society of Surgical Oncology (SSO)
  • Americas Hepato Pancreato Biliary Association (AHPBA)
  • American Society of Clinical Oncology (ASCO)
  • Connective Tissue Oncology Society (CTOS, Sarcoma)
  • American Association of Cancer Research (AACR)
  • Johns Hopkins Surgery, Old Hands Club
  • American College of Surgeons
  • North Pacific Surgical Association
  • Portland Surgical Society
  • Mackenzie Surgical Society
  • Alpha Omega Alpha (AOA) Medical Honor Society
  • SWOG (Southwest Oncology Group) Surgery and Gastrointestinal Oncology Committee Member
  • Trans Atlantic Retroperitoneal Sarcoma Working Group (TARPSWG), Member
  • International Cholangiocarcinoma Research Network, Surgical Oncology Committee (ICRN)

Areas of interest

  • Early Detection of cancer recurrence
  • Liver-directed therapies for metastatic and primary liver cancers
  • Early phase clinical trial development in hepatopancreatobiliary oncology
  • Surgical management of giant retroperitoneal sarcoma
  • Risk factors for developing intrahepatic cholangiocarcinoma
  • Cancer immunology



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