Division of Reproductive and Developmental Sciences

Overview

The mission of the Division of Reproductive and Developmental Sciences is to perform basic and applied research that will increase our understanding of primate reproduction and embryonic/fetal development and to use this knowledge to intervene in reproductive disorders, regulate fertility, as well as ensure normal fetal and neonatal development. Research projects span the continuum of reproductive processes, from gamete and embryo development, through pregnancy initiation, placental function and maternal-fetal development, to delivery and neonatal health. Research groups utilize macaque species and baboons for whole animal, cellular and molecular studies of direct relevance to women’s and child health. Researchers are creating and using nonhuman primate models to investigate reproductive and developmental physiology, with the goal of considering the etiology, diagnosis, treatment of reproductive and developmental pathologies, as well as developing novel approaches to contraception. By combining assisted reproductive technologies with newer genome editing techniques, Division scientists are also involved in creating nonhuman primate models of human diseases to understand their pathophysiology and develop the next generation of precision medicine-based treatments.

There are 21 scientists comprising the Division. Some have primary appointments in other ONPRC Divisions or Departments within the OHSU School of Medicine but include reproductive and developmental sciences as a major part of their research. While fostering the individuality of the investigator’s research, the overarching theme is the formation of interdisciplinary groups performing translational research on critical issues in women’s reproductive health. Division faculty members are also committed to training the next generation of reproductive and developmental scientists, particularly those who seek to improve human health by using clinically relevant nonhuman primate models.