Photo of Ov D. Slayden, Ph.D.

Ov D. Slayden Ph.D.

  • (503) 346-5435
    • Associate Professor Oregon National Primate Research Center
    • Associate Professor of Obstetrics and Gynecology School of Medicine
    • Program in Molecular and Cellular Biosciences School of Medicine

Ov Daniel Slayden is a Professor in the Division of Reproductive Sciences at Oregon National Primate Research Center and has joint appointments in the Department of Obstetrics and Gynecology, and in Physiology and Pharmacology in the School of Medicine, OHSU. Dr. Slayden is a co-Investigator and Scientific Director of the Oregon Permanent Contraception Research Center (OPERM).  He received his B.A. and M.A. degrees in Biology from Sonoma State University, and earned a Ph.D. in Biochemistry and Animal Science at Oregon State University. Dr. Slayden moved to the Center in 1991 after being awarded a Reproductive Biology Training Fellowship through the Department of Physiology at OHSU. 

Areas of interest

  • Endometriosis
  • Contraception
  • PCOS
  • Hormonal Regulation of the Reproductive Tract

Education

  • B.A., Sonoma State University 1979
  • M.A., Sonoma State University 1984
  • Ph.D., Oregon State University 1991
  • Fellowship:

    • Postdoctoral Fellowship – ONPRC; 1995

Honors and awards

  • 2007 Technology Innovation Award, Oregon Health & Science University: A Top 10 Sponsored Research Awardee for 2007
  • 2008 Technology Innovation Award, Oregon Health & Science University: A Top Five Sponsored Research Awardee for 2008
  • 2009 Technology Innovation Award, Oregon Health & Science University: A Top Five Sponsored Research Awardee for 2009
  • 2010 Technology Innovation Award, Oregon Health & Science University: A Top Five Sponsored Research Awardee for 2010
  • 2011 Technology Innovation Award, Oregon Health & Science University: A Top Sponsored Research Awardee for 2011
  • 2013 Technology Innovation Award, Oregon Health & Science University: A Top Sponsored Research Awardee for 2013
  • 2014 Technology Innovation Award, Oregon Health & Science University: A Top Sponsored Research Awardee for 2014
  • 2015 Technology Innovation Award, Oregon Health & Science University: A Top Sponsored Research Awardee for 2015
  • 2016 Technology Innovation Award, Oregon Health & Science University: A Top Sponsored Research Awardee for 2016
  • 2017 ASRM Star Award; Recognition for at least nine out of ten successive years presenting at ASRM Scientific Congresses

Memberships and associations

  • American Association for Advancement of Science
  • American Association for Cell Biology
  • American Society for Reproductive Medicine
  • American Society of Mammalogists
  • Endocrine Society
  • Sigma Xi, Oregon State University Chapter
  • Society for Gynecologic Investigation
  • Society for the Study of Reproduction

Publications

  • "Premenstrual and menstrual changes in the macaque and human endometrium" Annals of the New York Academy of Sciences  2002
  • "In vitro and in vivo characterization of a novel nonsteroidal, species-specific progesterone receptor modulator, PRA-910."   2007
  • "The rhesus macaque as an animal model for pelvic organ prolapse" American Journal of Obstetrics and Gynecology  2002
  • "In vivo and in vitro effects of a cyclopropenoid fatty acid on ovine corpus luteum function" Endocrinology December 1990
  • "Role of nonhuman primate models in the discovery and clinical development of selective progesterone receptor modulators (SPRMs)" Reproductive Biology and Endocrinology October 9 2006
  • "A role for the androgen receptor in the endometrial antiproliferative effects of progesterone antagonists" Steroids November 2003
  • "Progesterone suppresses an oxytocin-stimulated signal pathway in COS-7 cells transfected with the oxytocin receptor" Steroids December 22 2008
  • "Blockade of tubal patency following transcervical administration of polidocanol foam" Contraception  2014
  • "Effects of keratinocyte growth factor in the endometrium of rhesus macaques during the luteal-follicular transition" Journal of Clinical Endocrinology and Metabolism  2000
  • "Anti-proliferative effects of progesterone antagonists in the primate endometrium" Reproduction  2002
  • "Assessment of progestin-only therapy for endometriosis in macaque" Journal of Medical Primatology February 2008
  • "Gonadotrophic and local control of the developing corpus luteum in rhesus monkeys" Human Reproduction  1993
  • "Radioligand binding assay of progesterone receptors in the primate corpus luteum after in vivo treatment with the 3β-hydroxysteroid dehydrogenase inhibitor, trilostane" Journal of Clinical Endocrinology and Metabolism August 1994
  • "Progesterone receptor antagonists and the endometrial antiproliferative effect" Seminars in Reproductive Medicine February 2005
  • "A chronic, low-dose regimen of the antiprogestin ZK 137 316 prevents pregnancy in rhesus monkeys" Human Reproduction  1998
  • "A critical period of progesterone withdrawal precedes menstruation in macaques" Reproductive Biology and Endocrinology October 9 2006
  • "Progesterone antagonists increase androgen receptor expression in the rhesus macaque and human endometrium" Journal of Clinical Endocrinology and Metabolism  2001
  • "Novel progesterone receptor modulators" Bioorganic and Medicinal Chemistry Letters December 1 2012
  • "Evidence for a potential role of neuropeptide Y in ovine corpus luteum function" Domestic Animal Endocrinology February 2010
  • "Action of a cyclopropenoid fatty acid on the corpus luteum of pregnant and nonpregnant ewes" Biology of Reproduction  1994
  • "Endometrial CXCL13 expression is cycle regulated in humans and aberrantly expressed in humans and rhesus macaques with endometriosis" Reproductive Sciences April 15 2015
  • "Suppressive action of gonadotropin-releasing hormone and luteinizing hormone on function of the developing ovine corpus luteum." Journal of Animal Science August 1990
  • "Progesterone-induced gene expression in uterine epithelia" Biology of Reproduction November 2008
  • "Induced endometriosis in nonhuman primates" Biology of Reproduction February 2013
  • "The role of scientists and clinicians in raising public support for animal research in reproductive biology and medicine" Biology of Reproduction February 2013
  • "Matrix metalloproteinase expression in Macaca mulatta endometrium" Biology of Reproduction December 1998
  • "Cyclic remodeling of the nonhuman primate endometrium" Seminars in Reproductive Medicine  2014
  • "Reversible suppression of menstruation with progesterone antagonists in rhesus macaques" Human Reproduction  2001
  • "Immunocytochemical localization of androgen receptors in brains of developing and adult male rhesus monkeys" Endocrine  1998
  • "Erratum" Journal of Medical Primatology August 2008

Additional information

Edit profile