Victoria HJ Roberts, Ph.D.
- Associate Professor, Oregon National Primate Research Center
- Obstetrics and Gynecology, School of Medicine
Biography
Victoria Roberts, Ph.D., is an Associate Professor in the Division of Developmental and Reproductive Sciences at the Oregon National Primate Research Center. Her overall research objective is to understand the developing placenta. Within this area of research, Dr. Roberts utilizes both in vivo and in vitro methods to investigate placental function.
Through the use of advanced imaging modalities such as ultrasound and magnetic resonance imaging (MRI), Dr. Roberts and colleagues have made in vivo assessments of placental hemodynamics in several nonhuman primate models of pregnancy complications, and in studies conducted in pregnant women. Gaining a better understanding of the placenta in utero may assist in the clinical management of pregnancies that are found to be at-risk for placental insufficiency.
Furthermore, Dr. Roberts performs in vitro functional experiments in placental tissue post-delivery. When combined with structural assessments of the tissue, these in vitro studies provide insight as to the mechanisms of action that regulate function, and reveal the developmental changes that occur in adverse in utero conditions that underlie pregnancy complications.
Education and training
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Degrees
- B.S., 1999, University of Reading
- Ph.D., 2004, University of Manchester
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Fellowship
- Postdoctoral Fellow, University of Cincinnati, Cincinnati, OH, 2008
Memberships and associations:
- Member, International Federation of Placenta Association, 2001-present
- Member, Developmental Origins of Adult Disease Society, 2006-present
- Member, Society for Reproductive Investigation, 2006-present
Areas of interest
- Placental physiology
- Developmental biology
- In vitro model systems
- In vivo imaging
Additional information
Honors and awards
- 2016, SMFM Research Excellence Award, Society for Maternal Fetal Medicine, Atlanta
- 2017, SMFM Research Excellence Award, Society for Maternal Fetal Medicine, Las Vegas
- 2018, American Journal of Obstetrics & Gynecology, Research Excellence Award, Highly cited publication
- 2019, American Journal of Obstetrics & Gynecology, Research Excellence Award, Highly cited publication
Publications
Selected publications
- MC Schabel#, VHJ Roberts#, KJ Gibbins, M Rincon, JE Gaffney, AD Streblow, AM Wright, JO Lo, B Park, CD Kroenke, K Szczotka, NR Blue, JM Page, K Harvey, MW Varner, RM Silver, AE Frias (2022) Assessing placental function across gestation: a multi-institutional study of BOLD-MRI for the prediction of adverse pregnancy outcomes. PLOS One. Jul 19;17(7):e0270360. PMID: 35853003 #Joint first author
- JL Rosenkrantz, JE Gaffney, VHJ Roberts, L Carbone and SL Chavez (2021) Transcriptomic comparison of primate placentas reveals the utility of novel rhesus macaque trophoblast cell lines for investigating human placentation. Biology of Reproduction. Jun 21;19(1):127. PMID: 34154587; PMCID: PMC8218487.
- AJ Hirsch#, VHJ Roberts#, PL Grigsby, N Haese, MC Schabel, X Wang, JO Lo, Z Liu, CD. Kroenke, JL Smith, M Kelleher, R Broeckel, CN Kreklywich, CJ Parkins, M Denton, P Smith, V DeFilippis, W Messer, JA Nelson, JD Hennebold, M Grafe, L Colgin, A Lewis, et al, (2018) Zika virus infection in pregnant rhesus macaques causes placental dysfunction and immunopathology. Nature Communications Jan 17;9(1):263 PMID: 29343712; PMCID: PMC5772047. #Joint first author
- VHJ Roberts, TK Morgan, MD, P Bednarek, M Morita, GJ Burton, JO Lo and AE Frias (2017) Early first trimester uteroplacental flow and the progressive disintegration of spiral artery plugs: New insights from contrast-enhanced ultrasound and tissue histopathology. Human Reproduction Dec 1;32(12):2382-2393. PMID: 29136193; PMCID: PMC6251668.
- MC Schabel, VHJ Roberts, JO Lo, S Platt, KA Grant, AE Frias, and CD Kroenke (2015) Functional Imaging of the non-human primate placenta with endogenous BOLD contrast. Magnetic Resonance in Medicine, Nov;76(5):1551-1562. PMID: 26599502; PMCID: PMC4879634.
- AE Frias, MC Schabel, VHJ Roberts, A Tudorica, PL Grigsby, KY Oh, and CD Kroenke (2015) Using Dynamic Contrast Enhanced MRI to quantitatively characterize maternal vascular organization in the primate placenta. Magnetic Resonance in Medicine, 73(4) 1570-8. PMID: 24753177; PMCID: PMC4487918.
- THH Coorens, A Guillaumet-Adams, R Kovner, RL Linn, VHJ Roberts, A Sule, PM Van Hoose, and the dGTEx Consortium (2025) The human and non-human primate developmental GTEx projects. Nature Jan;637(8046):557-564. PMID: 39815096.
- A Melbourne, MC Schabel, AL David, VHJ Roberts (2024) Magnetic Resonance Imaging of Placental Intralobule Structure and Function in a Pre-clinical Nonhuman Primate Model. Biology of Reproduction. 110(6):1065-1076. PMID: 38442734.
- Cilvik SN, Sullivan MN, Hobbs TR, Castro JN, Wessel BM, Harrison HF, Roberts VHJ. Application of Chorionic Villus Sampling to Longitudinal Studies in Pregnant Non-Human Primate Models. Animals (Basel). 2026 Jan 24;16(3):374. doi: 10.3390/ani16030374. PMID: 41681355; PMCID: PMC12897227.
- Kroenke CD, Canavesi I, Castro JN, Karpf JA, Khurana R, Holloway MM, Palha MS, Legenzov EA, Crilly NP, Epel B, Driesschaert B, Rawal VH, Kao JPY, Buehler PW, Roberts VHJ, Kotecha M. Trityl OXO71 Pharmacokinetics and Distribution in Rhesus Macaques. Magn Reson Med. 2026 Apr;95(4):2459-2468. doi: 10.1002/mrm.70214. Epub 2025 Dec 15. PMID: 41399038; PMCID: PMC12965390.
- Wessel BM, Castro JN, Harrison HF, Scottoline BP, Wilcox MC, Baldwin MK, Roberts VHJ. Development of a trophoblast organoid resource in a translational primate model. Organoids. 2025 Dec;4(4):24. doi: 10.3390/organoids4040024. Epub 2025 Oct 8. PMID: 41394426; PMCID: PMC12700638.