Aortic Disease Clinical Trials

The aortic clinical trials team is interested in seeing how exciting new aortic devices and drugs can help to improve the outcomes and quality of life for those living with aortic diseases.

Feel free to call or e-mail the Knight Cardiovascular Institute research team at 503-418-1964 or by emailing heartresearch@ohsu.edu. You will then be forwarded to the appropriate research team member who will be able to see if you qualify for any of the clinical trials being offered at OHSU. 

Fibrillin Surveillance Study

Use of Plasma-detected Fibrillin Peptide Fragments for pre- and Post-operative Aortic Aneurysm and Dissection Surveillance

Primary investigator:

Cherrie Abraham, M.D., F.R.C.S.C.

Sub-investigators:

Protocol number:

IRB00016252

Study purpose:

This study aims to determine the sensitivity of circulating fibrillin fragment levels to detect and surveillance changes in aortic pathology pre- and post-operatively.

Contact:

Derek Darby (Study Coordinator)
503-418-1964
heartresearch@ohsu.edu 

GORE® TBE® trial

Evaluation of the GORE® TAG® Thoracic Branch Endoprosthesis (TBE Device) in the Treatment of Lesions of the Aortic Arch and Descending Thoracic Aorta

Primary investigator:

Cherrie Abraham, M.D., F.R.C.S.C.

Sub-investigators:

Protocol number:

IRB00016197

Study purpose:

This is a study device trial that aims to evaluate the safety and effectiveness of the thoracic branch endoprosthesis (TBE) in subjects with aortic lesions. 

Contact:

Derek Darby (Study Coordinator)
503-418-1964
heartresearch@ohsu.edu 

Zenith p-Branch Study

Primary investigator:

Cherrie Abraham, M.D., F.R.C.S.C.

Sub-investigators:

Protocol number:

IIRB00015370

Study purpose:

This clinical investigation is intended to evaluate the safety and effectiveness of the Zenith® p-Branch™ in combination with Atrium iCAST™ covered stents for the treatment of pararenal or juxtarenal aortic aneurysms.

Contact:

Derek Darby (Study Coordinator)
503-418-1964
heartresearch@ohsu.edu