Skin Condition Clinical Trials

A woman describing what a clinical trial is to a prospective patient.

OHSU Department of Dermatology's Clinical Research Team provides expertise in clinical research. We offer many different clinical  trials throughout the year throughout various skin conditions. Most trials have a limited number of spots or time allowed to enroll patients.

Currently enrolling trials

Adult Eczema Observational Study (12+ years)
The purpose of this study is to assess the long-term effectiveness and safety of adults who are currently taking DUPIXENT for Atopic Dermatitis. Participants must be initiating treatment with DUPIXENT for Atopic Dermatitis according to the country-specific prescribing information.

Eczema Herpeticum Study (3 yrs to 85 yrs)
The purpose of this study is to determine why some individuals with atopic dermatitis are at higher risk for recurrent skin infections with herpes simplex virus (HSV).

Pediatric Eczema Study (6 mo to 6 yrs)
The purpose of this study is to determine the safety and efficacy of the investigational drug (dupilumab) in children six months to six years of age who've been diagnosed with atopic dermatitis, also known as eczema.

Pediatric Eczema Study (2 to <12 yrs)
This study is to evaluate the safety and tolerability of multiple doses of the study drug (upadacitinib) in pediatric subjects with severe atopic dermatitis.
 

Adult Genital Psoriasis Study (<18 yrs)
This study is to evaluate the effectiveness of oral apremilast (study drug), compared to placebo, in subjects with moderate to severe genital psoriasis.

War on Melanoma: Enlisting a cohort of melanoma survivors and their families
The purpose of this data repository, called the Melanoma Community Registry, is to develop a prospective cohort of melanoma patients, family members and friends (controls). This registry will serve as a data repository for future IRB-approved research and thus will collect, store and share data with melanoma researchers for an indeterminate period of time. In addition, our repository will contain identifying codes/numbers that are links to data/samples in other relevant databases. Additionally, it is intended to deliver a ready-to-act group of volunteers to participate in the War on Melanoma campaign to include such things as attending educational symposiums and using their networks to increase awareness of the issue. There is no existing nationwide registry for melanoma research. As patient-centered research advances, a resource like this is needed and can serve as a model.

Adult Palmoplantar Pustulosis (PPP) Study
The purpose of this randomized study is to collect safety and effectiveness information about the study drug (ANB019) for adults who have Palmoplantar Pustulosis (PPP).

Not sure if you have palmoplantar pustulosis? Visit PPP study page to learn more.

Impact of Pediatric Skin Disorders Study (8-17 yrs)
This study, The "Big" Study, is to understand the severity and the type of stigma experienced across different kinds of skin conditions and therefore help identify methods of intervention to lessen the impact of skin disorders.

Immune-Mediated Inflammatory Skin Conditions (IMISC) Observational Study (all ages)
The purpose of this study is to observe patients of all ages being treated for IMISC (Atopic Dermatitis, Psoriasis, Alopecia, Vitiligo, Hidradenitis Suppurative). In addition to the study database, a biospecimen repository will be included in order to perform studies on biomarkers of response.

Adult Pityriasis Rubra Pilaris (PRP) Study
The purpose of this study is to determine whether guselkumab provides clinical improvement for subjects with pityriasis rubra pilaris (PRP).

Adult Hidradenitis Suppurativa (HS) Study
The purpose of this clinical research study is to find out if secukinumab (study drug) is safe and has beneficial effects in patients with hidradenitis suppurativa (HS). In addition, it will determine if secukinumab works better if given more frequently: once every 2 weeks instead of once a month.

Adult Squamous Cell Carcinoma (CSCC) Study
The purpose of this study is to determine, long term, how well the drug, cemiplimab, works in patients diagnosed with Cutaneous Squamous Cell Carcinoma (CSCC, a type of skin cancer).

Frequently Asked Questions

A clinical trial is an organized activity to learn more about a problem or answer questions. Many different kinds of studies are conducted. For example studies may be done to:

  • Test if a product, such as a drug or equipment, is safe and effective.
  • Find out what education practices work best.
  • Determine the best way to treat or prevent an illness.
  • Survey or an interview to understand needs, problems, or feelings people have about an important topic.

Frequently asked questions (FAQ's) about clinical trials.

There are many reasons to take part in research. You may want to:

  • Help other people.
  • Help find a cure for an illness.
  • Help scientists find out more about how the human body and mind work.

If you decide to take part in a research study, you do so as a volunteer. That means you decide whether or not you will take part. You can say "no". If you choose to do so, you have many important rights, including the right to decide that you want to quit the study at any time.

Find out more about clinical trial studies on the ClinicalTrials.gov site, created by the U.S. National Institutes of Health.

Visit the Clinical Trials website.

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