Skin Condition Clinical Trials

A woman describing what a clinical trial is to a prospective patient.

OHSU Department of Dermatology's Clinical Research Team provides expertise in clinical research. We offer many different clinical  trials throughout the year throughout various skin conditions. Most trials have a limited number of spots or time allowed to enroll patients.

Currently enrolling trials

Adult and Adolescent Eczema Study (6+ years)
The purpose of this study is to assess the safety and efficacy of the study cream vs. placebo administered daily to individuals with atopic dermatitis (eczema).

Pediatric Eczema Study (6 mo. to 12 years)
The purpose of this study is to evaluate the safety and tolerability of the study drug in pediatric individuals with severe atopic dermatitis (eczema).

Adult Eczema Observational Study (12+ years)
The purpose of this study is to assess the long-term effectiveness and safety of adults who are currently taking DUPIXENT for atopic dermatitis (eczema). Participants must be initiating treatment with DUPIXENT for Atopic Dermatitis according to the country-specific prescribing information.

Psoriasis Registry Study
The primary objective for this registry is to study the natural history of psoriasis, the prevalence and incidence of other conditions, and certain side effects, as well as to collect information about effectiveness and safety of approved psoriasis treatments.

Adult Skin Fluorescence Imaging Study (18+ years)
The purpose of this study is to learn about how skin fluorescence imaging (SFI) can capture information about changes occurring with a mole to assess the mole's potential to develop into a melanoma.

War on Melanoma: Enlisting a cohort of melanoma survivors and their families
The purpose of this data repository, called the Melanoma Community Registry, is to develop a prospective cohort of melanoma patients, family members and friends (controls). This registry will serve as a data repository for future IRB-approved research and thus will collect, store and share data with melanoma researchers for an indeterminate period of time. In addition, our repository will contain identifying codes/numbers that are links to data/samples in other relevant databases. Additionally, it is intended to deliver a ready-to-act group of volunteers to participate in the War on Melanoma campaign to include such things as attending educational symposiums and using their networks to increase awareness of the issue. There is no existing nationwide registry for melanoma research. As patient-centered research advances, a resource like this is needed and can serve as a model.

Melanoma Tissue Bank Consortium: A Multi-Center Repository of Biospecimens and Data for Future Use
The purpose of this study is for the Melanoma Tissue Bank Consortium to create a repository of leftover tissue and other human biospecimens (such as skin, blood, urine, saliva, and stool) and medical and annotating data (such as test and treatment results, age, gender, and history of sun exposure) in order to study melanoma.

Adult Cutaneous Squamous Cell Carcinoma (CSCC) Study
The purpose of the study is to determine, long term, how well the drug, cemiplimab, works in patients diagnosed with Cutaneous Squamous Cell Carcinoma (CSCC, a type of skin cancer).

Isolation and analysis of circulating tumor cells (CTCs) and nucleic acids from patient blood specimens
The purpose of this study is to collect blood specimens to study with the purpose of identifying circulating markers of cancer for early detection.

Adult Pityriasis Rubra Pilaris Study
The purpose of this study is to determine whether guselkumab provides clinical improvement for subjects with pityriasis rubra pilaris.

Adult Bullous Pemphigoid Study
The main purpose of this study is to investigate whether the study drug, dupilumab, is effective and safe for treatment of bullous pemphigoid.

Immune-Mediated Inflammatory Skin Conditions Observational Study
The purpose of this study is to observe adult and pediatric patients being treated for Immune-Mediated Inflammatory Skin Conditions. In addition to the study database, a biospecimen repository will be included in order to perform studies on biomarkers of response.

Frequently Asked Questions

A clinical trial is an organized activity to learn more about a problem or answer questions. Many different kinds of studies are conducted. For example studies may be done to:

  • Test if a product, such as a drug or equipment, is safe and effective.
  • Find out what education practices work best.
  • Determine the best way to treat or prevent an illness.
  • Survey or an interview to understand needs, problems, or feelings people have about an important topic.

Frequently asked questions (FAQ's) about clinical trials.

There are many reasons to take part in research. You may want to:

  • Help other people.
  • Help find a cure for an illness.
  • Help scientists find out more about how the human body and mind work.

If you decide to take part in a research study, you do so as a volunteer. That means you decide whether or not you will take part. You can say "no". If you choose to do so, you have many important rights, including the right to decide that you want to quit the study at any time.

Find out more about clinical trial studies on the site, created by the U.S. National Institutes of Health.

Visit the Clinical Trials website.

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