Skin Condition Clinical Trials

A woman describing what a clinical trial is to a prospective patient.

OHSU Department of Dermatology's Clinical Research Team provides expertise in clinical research. We offer many different clinical  trials throughout the year throughout various skin conditions. Most trials have a limited number of spots or time allowed to enroll patients.

Currently enrolling trials

Adult Eczema Study (18 yrs +)
This study is to assess the efficacy of four dose regimens of KHK4083 compared to placebo as measured by the change from baseline. In addition to evaluate the safety of multiple injections of KHK4083 in subjects with moderate-to-severe atopic dermatitis.

Adult Eczema Study (18 yrs to 65 yrs)
The purpose of this study is to determine how study drug dupilumab affects the amount of bacteria on the skin, the skin's water loss and the immune system for subjects with moderate-to-severe atopic dermatitis.

Eczema Herpeticum Study (3 yrs to 85 yrs)
The purpose of this study is to determine why some individuals with atopic dermatitis are at higher risk for recurrent skin infections with herpes simplex virus (HSV).

Pediatric Eczema Study (2 to <12 yrs)
This study is to evaluate the safety and tolerability of multiple doses of the study drug (upadacitinib) in pediatric subjects with severe atopic dermatitis.

Adolescent Eczema Study (12 to <18 yrs)
This study is to learn about how well the study drug may work to treat atopic dermatitis compared to a placebo in subjects aged 12 to 18 with moderate-to-severe atopic dermatitis.

There are no currently enrolling psoriasis trials at this time. Please use the 'contact us' form to be placed on a contact list for future trials.

War on Melanoma: Enlisting a cohort of melanoma survivors and their families
The purpose of this data repository, called the Melanoma Community Registry, is to develop a prospective cohort of melanoma patients, family members and friends (controls). This registry will serve as a data repository for future IRB-approved research and thus will collect, store and share data with melanoma researchers for an indeterminate period of time. In addition, our repository will contain identifying codes/numbers that are links to data/samples in other relevant databases. Additionally, it is intended to deliver a ready-to-act group of volunteers to participate in the War on Melanoma campaign to include such things as attending educational symposiums and using their networks to increase awareness of the issue. There is no existing nationwide registry for melanoma research. As patient-centered research advances, a resource like this is needed and can serve as a model.

Ixekizumab in the Treatment of Pityriasis Rubra Pilaris (PRP)
The purpose of this study is to determine whether ixekizumab provides clinical improvement for adult subjects with pityriasis rubra pilaris (PRP).

Patidegib in Reduction of Basal Cell Carcinomas (BCCS) Disease Burden in Subjects with Basal Cell Nevus Syndrome.
The purpose of this study is to find out if patidegib topic gel (referred to as the study gel) is beneficial and safe in reducing Basal Cell Carcinomas (BCC) in people with Basal Cell Nevus Syndrome (BCNS).

C0251002: A Phase 2A, Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Efficacy, Safety, and Tolerability of PF 06823859 in Adult Subjects with Dermatomyositis
The purpose of this study is to learn more about Dermatomyositis (DM). In this study, we will learn about a drug called PF-06823859. PF-06823859 will be called “the study drug”. We want to learn: If the study drug is better at treating DM than the placebo (A placebo looks like the study drug but does not contain any active drug.), if the study drug is safe and, what side effects are caused by the study drug.

Frequently Asked Questions

A clinical trial is an organized activity to learn more about a problem or answer questions. Many different kinds of studies are conducted. For example studies may be done to:

  • Test if a product, such as a drug or equipment, is safe and effective.
  • Find out what education practices work best.
  • Determine the best way to treat or prevent an illness.
  • Survey or an interview to understand needs, problems, or feelings people have about an important topic.

Frequently asked questions (FAQ's) about clinical trials.

There are many reasons to take part in research. You may want to:

  • Help other people.
  • Help find a cure for an illness.
  • Help scientists find out more about how the human body and mind work.

If you decide to take part in a research study, you do so as a volunteer. That means you decide whether or not you will take part. You can say "no". If you choose to do so, you have many important rights, including the right to decide that you want to quit the study at any time.

Find out more about clinical trial studies on the ClinicalTrials.gov site, created by the U.S. National Institutes of Health.

Visit the Clinical Trials website.