For Researchers

Researcher speaking with colleague, viewing brain scans on computer
Dr. Jeffrey Kaye, Director of the Layton Aging and Alzheimer's Research Center

An Alzheimer's Disease Center

The Layton Aging and Alzheimer's Disease Center is one of the 31 NIA Alzheimer's Disease Centers in the U.S. and the only one of its kind in Oregon. Our center is recognized as a national leader in dementia care and research.

Administrative Core

The Administrative Core oversees and sets the research direction for the Layton Center. This Core fosters new and innovative research relevant to brain aging, recruits new investigators, oversees cross-ADC collaborations and multicenter studies, coordinates grant-related activities, and manages financial resources. Working behind-the-scenes, the Administrative Core also acts as a liaison between all the individual Cores and between individual investigators, clinicians, educators and the community.

Director: Dr. Jeffrey Kaye, M.D.

For more information: Message Tracy Zitzelberger at  or call 503-494-7198

Clinical Core

The goal of the Clinical Core is to maintain an active group of research participants, with or without dementia, to support a variety of studies. This group includes the underserved African American senior population. Research coordinators screen research participants, perform clinical tests and facilitate clinical trials and studies. The Core also provides data, biological specimens, and expertise to national data sharing initiatives and approved regional and national investigations.

Director: Dr. Jeffrey Kaye, M.D.

For more information: Message Dr. Jeffrey Kaye at 

Data Management & Statistics Core

The Data Management & Statistics Core receives, stores, and manages, and analyzes data generated by the other Cores and by other research projects at the Layton Center. Investigators within this Core provide guidance on statistical analysis, research study design, sample size estimations, interpretation of study findings and related issues. Working collaboratively with the Neuroimaging, Clinical, Biomarker and Neuropathology Cores, this Core shares clinical cohort data with investigators and maintains secure platforms for data exchange.

Director: Dr. Hiroko Dodge, Ph.D.

For more information: Message Robin Guariglia at  or call 503-494-6977

Learn more about the Center's database, see how to make a data request and view requirements for submitting manuscripts for publication. Read more.

Outreach, Recruitment & Education Core

The Outreach, Recruitment and Education Core develops and manages a wide array of programs to increase public awareness and understanding of Alzheimer's disease and research at the Layton Center. One main goal is building relationships with the community and networking with other organizations to provide educational resources and recruit participants for studies, a particular focus being underserved rural communities, low-income populations and minority groups. The Core also organizes meetings, lectures and workshops throughout Oregon and publishes a newsletter twice a year.

Director: Dr. Allison Lindauer, Ph.D., N.P.

For more information: Message Natasha Spoden at  or call 503-494-6370

Learn about the Layton Center's educational programs for the public and health care professionals. View more.

Neuropathology Core

The Neuropathology Core collects, characterizes, and stores brain donations from clinical study participants at the Oregon Brain Bank, in accordance with established protocols. By creating a safeguarded yet accessible repository of brain tissue and neuropathological data, the Core is able to perform diagnostic evaluations of autopsy tissue and facilitate research about brain aging. The Core provides tissue to investigators researching aging and dementia and teaches trainees about current neuropathological classifications of neurodegenerative diseases.   

Director: Dr. Randall Woltjer, M.D., Ph.D.

For more information about the Oregon Brain Bank: Message Dr. Randall Woltjer at  or call 503-494-8276

Learn more about tissue requests and the Core's protocols. View more.

Biomarker Core

The Biomarker Core collects and stores tissue samples, biomarkers, family history data and genotype data from subjects recruited by the Clinical Core. (These can include markers in blood, spinal fluid, patterns of activity on MRI scans or scores on cognitive tests). Biomarker data is prepared and distributed to investigators that are a part of ongoing national research studies, in order to foster collaborative research about neurodegenerative disease.  

Director: Dr. Joe Quinn, M.D.

For more information: Message Dr. Joe Quinn, M.D. at  or call 503-494-7234 

Learn what type of family history and genotype data the Core collects and learn how to request a biomarker data or tissue sample. View more.

Neuroimaging Core

The Neuroimaging Core focuses on detecting early brain changes associated with cognitive decline and dementia, using the Neuroimaging Laboratory at the Layton Center. Participants undergo MRI, fMRI and PET scans for a wide array of studies. The Laboratory acts as an archival service, managing a library of thousands of digitized scans and other neuroimaging data. Investigators also receive advanced training in imaging techniques.  

Director: Dr. Lisa Silbert, M.D., M.C.R.

For more information: Message David Lahna at  or call 503-494-1266 

Learn about the current projects at the Neuroimaging Laboratory. View more.

Grant opportunities

Pilot and seed funding for research are key to bringing new investigators into the field. Additionally, funding helps established scientists expand the direction of their research. The Layton Center offers several pilot grant programs for new investigators or more experienced investigators who have novel ideas that may advance Alzheimer's research.

Pilot research awards

We have three pilot research awards, the Oregon Alzheimer's Disease Center (OADC) Pilot Program, the Oregon Roybal Center for Aging and Technology Pilot Program and the Oregon Partnership for Alzheimer's Research (OPAR) grant.

Funds for the OPAR grant have been made available by Oregonians through the Oregon Income Tax Charitable Checkoff Program.

To learn more about these annual awards - including application deadlines, project timelines and how to apply - click on the links.

 Oregon Roybal Center for Aging and Technology Pilot Program Oregon
Partnership for Alzheimer's Research
(OPAR)

Letter of Intent
Deadline /
Month Due

NovemberDecemberFebruary
Application Deadline / Month DueDecemberFebruaryApril
Project DatesApril 2019 - March 2020June 2019 - May 2020September 2019 - August 2020
Maximum Direct Costs

$30,000.

Number of awards: 2

$45,000.

Number of awards: 2

Up to $20,000 

Number of awards: 1

More Information