Male Contraception Study

This study is being done in order to investigate a combination hormonal gel Nestorone® and testosterone. The study gel that will be used in this study is experimental and being developed as a possible new method for male birth control.  PI: Alison Edelman, MD, MPH eIRB#21247

Cannabidiol and Oral Contraceptive Pills Study

The purpose of this study is to find out how cannabidiol, or CBD, affects birth control pills. PI: Shaalini Ramanadhan, MD; IRB# 20906

Curcumin Implant Study

The purpose of this study is to learn if a supplement called curcumin, the active ingredient in the spice turmeric, taken for 30 days can reduce the number of days of vaginal bleeding in women using the contraceptive implant (nexplanon or implanon). PI: Alison Edleman, MD, MPH IRB# 20645

Injectable Contraceptive Study

The purpose of this study is to investigate levonorgestrel butanoate (LB) as a possible long-acting and reversible injectable for contraception.  PI: Jeffrey Jensen MD, MPH eIRB# 20726

Do you need emergency contraception?

The purpose of this study is to assess how effective different doses of emergency contraception work at preventing pregnancy for women who weigh more an 176 lbs. PI: Alison Edelman, MD, MPH; IRB# 18441

Emergency contraception and BMI

The purpose of this study is to improve effectiveness of orally-dosed emergency contraceptives for women of higher BMIs. PI: Alison Edelman, MD, MPH; IRB# 16291

Liletta® IUD and heavy menstrual bleeding

The purpose of this study is to investigate the effectiveness of a hormonal IUD at treating very heavy menstrual bleeding. PI: Jeffrey Jensen, MD, MPH; IRB# 19016

Vaginal contraceptive ring

The purpose of this study is to investigate how effective a new vaginal contraceptive ring is at preventing pregnancy. PI: Jeffrey Jensen, MD, MPH; IRB# 18041

PRIORITY at OHSU

PRIORITY (Pregnancy CoRonavIrus Outcomes RegIsTrY) is a nationwide study of pregnant or recently pregnant women who have been tested for Coronavirus infection (COVID-19) or have been confirmed to have COVID-19. PI: Dr. Emmanuelle Pare; IRB# 21400

Effect of IV Iron on Neonatal Cord Blood Indices

The purpose of the study is to learn more about the use of intravenous iron therapy that may be helpful in treating iron deficiency in pregnant women and how the treatment compares to those who receive no therapy or oral iron therapy. We want to learn more about whether or not IV iron treatment is more effective than oral iron treatment in improving neonatal iron levels. Leonardo Pereira, MD, MCR eIRB# 20976

Pregnancy and Latent Labor Biomarkers and Symptoms to Predict Cervical Dilation at Hospital Admission

The purpose of the study is to learn about physical signals and symptoms that mean labor is close to starting and the early part of labor (sometimes called ‘latent labor’ or ‘early labor’) is occurring. We are hoping to find out more about physical markers (like heart rate) and symptoms (like contractions) that mean labor is close to starting and that the early part of labor is occurring. PI: Ellen Tilden, CNM, FACNM eIRB# 20328

Exercise and Pregnancy Study

This is a study designed to measure the effects of the timing of low-resistance or cardio exercise on blood sugars after eating a meal. We are inviting pregnant women at less than 30 weeks who have been diagnosed with gestational diabetes and are managing their diabetes with nutrition and lifestyle behaviors. PI: Amy Valent, DO; IRB: 20116

Continuous Core Body Temperature and the Onset of Parturition in Women

Dr. Elise Erickson, Ph.D., CNM is studying how body temperature changes before labor starts line up with when labor begins using an FDA approved device. You will be asked to wear a small flat device on your skin that measures body temperature continuously and answer a few questions each day about your activities until labor starts. PI: Dr. Elise Erickson, Ph.D., CNM; IRB#20059 

Target High-Throughput Methylome Analysis of Early and Late Onset Preeclampsia

The purpose of this study is to examine the genetic differences in early preeclampsia and late preeclampsia pregnancies of mothers and their babies and how those differences compare to women who do not have preeclampsia. PI: Kent Thornburg, PhD, IRB #19294

Chronic hypertension and pregnancy

This study is being done to evaluate what the best and safest treatment for mild chronic hypertension during pregnancy is for both mother and baby. PI: Leonardo Pereira, MD, MCR; IRB# 17011

Maternal well-being study

We are interested in working with pregnant women to reduce mood symptoms and promote well-being during pregnancy and postpartum. PI: Kristen Mackiewicz Seghete, PhD; IRB# 19004

Medical optimization and management of pregnancies with overt type 2 diabetes (MOMPOD)

The purpose of this study is to learn about the safety and effectiveness of the study drug metformin when added to insulin treatment to help treat type 2 and early diagnosed diabetes in pregnancy. The study is trying to find out if metformin can be used safely in pregnancy to improve diabetes care and reduce problems at birth. PI: Amy Valent, DO; IRB #18438

Oxytocin receptor DNA methylation and postpartum maternal outcomes

In this study we are tying to learn if genetics plays a role in why some women have too much bleeding after birth. We are also interested in knowing more about how women's physical and mental recovery goes in the first year after birth whether or not they have had too much bleeding and how it related to their genetics as well. PI: Elise Erickson, PhD, CNM; IRB# 18841

Placenta repository: A study of placental function in healthy and pathological pregnancies

Our long term goal is to identify pregnancies that are at risk of poor outcomes and to develop methods for prevention and treatment. PI: Leonardo Pereira, MD; IRB# 16328

Prenatal environment and child Health (PEACH) study

OHSU researchers are conducting a study that looks at how maternal diet and metabolic state during pregnancy might affect child brain development and behavior. You can help us by participating in our research. PI: Elinor Sullivan, PhD and Joel Nigg, PhD; IRB #18579

Roo study on mom and baby well-being

We are looking for pregnant people who have experienced difficulties with low mood, anxiety or high stress levels. We hope to learn if mindfulness groups can promote well-being and self-care during pregnancy and support infant brain development. PI: Alice Graham, PhD; IRB #19166

Rosacea course fluctuations during pregnancy: A longitudinal observational study

The purpose of this study is to characterize the course of rosacea severity throughout pregnancy. PI: Jon Hanifin, MD; IRB# 16647

VentFirst: A multicenter RCT of assisted ventilation during delayed cord clamping for micro-preemies

The purpose of this study is to determine whether delaying clamping of the umbilical cord up to 120 seconds and assisting breathing for extremely premature babies during that time reduces intraventricular hemorrhage (bleeding in the brain). PI: Jamie B. Warren, MD, MPH; IRB#15777

Perinatal Early Determinants of Immune Development

Help us determine factors that influence immune development in pregnancy and neonatal development. PI: Nicole Marshall, MD, MCR; eIRB: 20735

Overactive bladder study

The purpose of this research study is to determine if the urinary microbiome affects overactive bladder syndrome (OAB). Currently, not much is known about the cause of OAB. This study seeks to determine if bacteria in the urinary tract play a role in OAB. PI: Lisa Karstens, PhD and Rahel Nardos, MD; IRB # 10729

Overactive bladder study

The purpose of this research study is to determine if the urinary microbiome affects overactive bladder syndrome (OAB). Currently, not much is known about the cause of OAB; this study seeks to determine if bacteria in the urinary tract play a role in OAB. PI: Lisa Karstens, PhD and Rahel Nardos, MD; IRB # 10729

Liletta® IUD and heavy menstrual bleeding study

The purpose of this study is to investigate the effectiveness of a hormonal IUD at treating very heavy menstrual bleeding. PI: Jeffrey Jensen, MD, MPH; IRB# 19016

Cell Culture and Cervical Mucus

Cervical mucus is the fluid at the opening to the uterus, or womb. During a normal menstrual cycle, cervical mucus changes in response to two natural hormones that the ovaries make: estrogen and progesterone. Many birth control methods that women use prevent pregnancy by thickening this mucus, making it less likely for sperm to enter the uterus PI: Leo Han, MD, MPH; IRB#18776

Management of Pain from Endometriosis in Pre-Menopausal Women

The Women’s Health Research Unit is conducting a study to evaluate the safety and effectiveness of a new investigational medication, Linzagolix, for pain in women with endometriosis. PI: Jeffrey Jensen, MD, MPH; IRB# 19890.

TelAbortion study

The purpose of this study is to assess service provision of medical abortion through telemedicine. IRB# 15974

Personalized Genetic Medicine to Prevent Invasive Uterine Cancer and Unnecessary Hysterectomies

The purpose of the study is to learn if molecular testing of endometrial biopsies from women diagnosed with pre-invasive complex “hyperplasia” can show who will or will not respond to progestin treatment with placement of the Levonorgestrel Intrauterine Device (LNG IUD). PI: Terry Morgan, MD, PhD; IRB#19503

In partnership with the Knight Cancer Institute

Find current trials involving ovarian, uterine and cervical cancers