Ensayos Clínicos Disponibles en Español:

Tenemos personal que hablan Español. Para obtener más información o saber si usted califica para participar, llame a la línea confidencial de reclutamiento de la Unidad de Investigación Sobre la Salud Femenina al 503-494-3666 o escríbanos a whru@ohsu.edu.

Estudios disponibles en Español:

• Embarazo:
  • Tenemos estudios disponibles para participantes que están embarazadas. Para obtener más información o saber si usted calificaría para participar, llame a la Unidad de Medicina Materno Fetal (MFMU-por sus iniciales en Ingles) al 503-494-8742 o escribanos a mfmresearch@ohsu.edu.
• Uso de insulina inhalada en mujeres embarazadas con GDM (INHALE-GDM)
  • Este estudio se está realizando para averiguar qué tan bien la inhalación de insulina puede reducir su azúcar en la sangre después de una comida, comparada con la inyección de insulina estándar administrada con su comida. Creemos que inhalar insulina puede funcionar mejor, pero aún no lo sabemos, por lo que este estudio nos ayudará a averiguarlo. Participarán en el estudio 30 mujeres embarazadas de 5 centros de todo Estados Unidos. PI: Dra. Amy Valent, DO IRB#: 28056

Emergency Contraceptive Disparities Study

This study is being conducted to learn more about why some people are at greater risk for oral emergency contraceptive failure while others are not. We are hoping to find out if genetic differences impact the risk of emergency contraception failure. PI: Alison Edelman, MD, MPH; IRB# 24952

Ulipristal Acetate and Mammographic Density

This study is being conducted to determine if the oral emergency contraceptive pill containing ulipristal acetate (UPA, otherwise known as Ella) decreases breast density on mammograms. The drug used in this study is FDA-approved for emergency contraception but not for use in breast health. PI: Abigail Liberty, M.D.; eIRB#: 28348

OHSU CWH Center M randomized trial

The purpose of the study is to learn about ways to promote well-being and reduce stress and depression during pregnancy and after birth. We are hoping to find out how well Center M, a mindfulness-based group intervention for pregnant people delivered via telehealth, can help accomplish these goals. PI: Ellen Tilden, CNM, Ph.D., IRB #29027

CGM2 – Continuous glucose monitoring for management of type 2 diabetes in pregnancy

The purpose of this study is to provide pregnant people with type 2 diabetes an opportunity to participate in a project that will help us understand if using CGM in pregnancy can improve sugars and lower pregnancy complications compared to our current standard blood sugar monitoring using fingersticks. PI: Amy Valent, DO, IRB#: 27883

GLOW – Stelo Real-Time CGM Use Postpartum for Lifelong Optimal Wellness

The purpose of this study is to determine the role of real-time continuous glucose monitoring (CGM) used during the year postpartum following delivery on 1) glucose (sugar) levels and 2) nutrition, lifestyle behaviors, and metabolic health among individuals with pregnancies complicated by GDM. PI: Amy Valent, DO, IRB#: 28947

IMAGINE - CGM for the Early Detection and Management of Hyperglycemia in Pregnancy

The purpose of this study is to find out if lowering glucose levels early in pregnancy will help reduce complications experienced by women and their babies. PI: Amy Valent, DO, IRB#: 28138

PRACTICE – Clinical Utility of a Predictive Model of Placental Insufficiency

The goal of this study is to better determine which pregnancies are at increased risk of complications like stillbirth, growth restriction, and preeclampsia. We will test a combination of lab tests, ultrasound studies, and risk factors to determine risk. The long-term goal is to use this improved risk assessment to improve monitoring of high risk pregnancies and prevent preventable stillbirths. PI: Karen J. Gibbins, MD, MSCI, eIRB#: 26808

IVIDA2 – Double-blind Placebo-controlled Multicenter Randomized Trial of Intravenous versus Oral Iron for Treating Iron-Deficiency Anemia in Pregnancy

The purpose of this is to determine the efficacy and safety of treating pregnant patients who have a diagnosis of iron deficiency anemia with an iron infusion compared to oral iron supplements and evaluating the effectiveness of both. Both study treatments are currently used in obstetric practice but have not been adequately compared in pregnancy.  PI: Ashley Benson, M.D., M.A., M.S., IRB#: 27128

TWINIRON – Cord blood ferritin levels in iron deficient pregnant women with twin gestations who receive iron therapy

The purpose of the study is to learn more about the effect of iron supplementation therapy on twin pregnancies and how this treatment may impact male and female fetuses. We want to learn more about whether female or male fetuses respond differently to iron therapy in order to improve treatment of iron deficiency anemia in pregnancy. PI: Leonardo Pereira, MD, MCR, IRB#: 25649

Exercise and Pregnancy Study

This is a study designed to measure the effects of the timing of low-resistance or cardio exercise on blood sugars after eating a meal. We are inviting pregnant women at less than 30 weeks who have been diagnosed with gestational diabetes and are managing their diabetes with nutrition and lifestyle behaviors. PI: Amy Valent, DO; IRB: 20116

Placenta Repository: A study of placental function in healthy and pathological pregnancies

The purpose of this repository is to learn about the placenta and uterus and how they function in pregnancy. The repository is a collection of samples and data that will be used to study processes occurring in normal, healthy pregnancies and in those complicated by disease. Our long term goal is to identify pregnancies that are at risk of poor outcomes and to develop methods for prevention and treatment. PI: Leonardo Pereira, MD; IRB# 16328

AZALEA - A Phase 3 Randomized, Placebo-Controlled, Double-Blind Study of Nipocalimab in Pregnancies at Risk for Severe Hemolytic Disease of the Fetus and Newborn (HDFN)

This study is to evaluate the efficacy and safety of Nipocalimab in reducing the risk of severe Hemolytic Disease of the Fetus and Newborn (HDFN) by preventing fetal anemia, hydrops fetalis, and related complications. PI: Leonardo Pereira, MD; IRB#:26246

GERANIUM – Global Prospective Hemolytic Disease of the Fetus and Newborn Registry

This global registry looks at prospective data on hemolytic disease of the fetus and newborn. The purpose of this research is to evaluate treatment effectiveness and outcomes of care for pregnant individuals and their corresponding fetuses, newborns, infants, and children at risk for Hemolytic Disease of the Fetus and Newborn (HDFN). PI: Leonardo Pereira, MD; IRB#: 28279

FRESSIA3-FNAIT – Multicenter, Open-Label, Randomized Study of Nipocalimab or IVIG in Pregnancies at Risk of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT)

The purpose of this study is to evaluate the efficacy, safety, and tolerability of Nipocalimab or IVIG in reducing the risk of severe bleeding complications in fetuses and neonates affected by Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT). PI: Leonardo Pereira, MD; IRB#: 27775

There are currently no studies enrolling specific to Menopause.

Endometrial Biopsy Study

[Please note: Enrollment for this study is currently on pause]

The purpose of this research is to study the endometrium (the tissue lining the uterus) in order to learn more about possible medical treatments for endometriosis, a painful condition in women in which the endometrium develops abnormally on the pelvic organs. PI: Jeff Jensen, MD MPH; IRB#: 5108

Cell Culture & Cervical Mucus

The purpose of this study is to help us determine how hormones impact the production of cervical mucus. PI: Leo Han, MD, MPH; IRB: 18776

Novel ultrasound technique in patients with fibroids

We know that blood flow is important for fibroid growth, but do not have reliable ways of monitoring changes in fibroid blood flow using ultrasound. We are attempting to understand how blood vessels impact uterine fibroid growth and to develop new ultrasound techniques for measuring these blood vessels. PI: Julia Tasset MD, MPH; eIRB# 29830

KYRIAD Study

The purpose of this study is to understand how well an investigational drug works in patients with functional hypothalamic amenorrhea, otherwise called FHA. PI: Elizabeth Rubin, MD; eIRB #29239

In partnership with the Knight Cancer Institute

Find current trials involving ovarian, uterine and cervical cancers

Understanding Heavy Menstrual Bleeding Study

This study may help us learn more about heavy menstrual bleeding and why it occurs. PI: Leo Hand, MD, MPH; IRB: 29370