Photo of Susan B. Olson, Ph.D.

Susan B. Olson Ph.D.

    • Professor of Molecular and Medical Genetics School of Medicine
    • Molecular and Medical Genetics Graduate Program School of Medicine
    • Program in Molecular and Cellular Biosciences School of Medicine

Dr. Olson`s special areas of interest include the role of chromosomal changes in fetal development and survival, cancer and genetic disease and the cellular and molecular basis of Fanconi Anemia. She currently is the Director of the Clinical Cytogenetic Laboratory at OHSU. Dr. Olson received her doctorate on 1984 from OHSU, which is also where she completed her fellowship in Medical Genetics-C.C.D.

  • Fellowship:

    • Medical Genetics-C.C.D., Oregon Health Sciences University, Portland

Memberships and associations

  • Clinical cytogenetics, 1987; Ph.D., Medical Genetics, 1987

Publications

  • "Two myeloid leukemia cases with rare FLT3 fusions." Cold Spring Harbor molecular case studies  In: , Vol. 4, No. 6, 01.12.2018.
  • "MYC immunohistochemical and cytogenetic analysis are required for identification of clinically relevant aggressive B cell lymphoma subtypes." Leukemia and Lymphoma  In: , 05.09.2017, p. 1-8.
  • "Functional Human Oocytes Generated by Transfer of Polar Body Genomes." Cell Stem Cell  In: , Vol. 20, No. 1, 05.01.2017, p. 112-119.
  • "Metformin improves defective hematopoiesis and delays tumor formation in Fanconi anemia mice." Blood  In: , Vol. 128, No. 24, 15.12.2016, p. 2774-2784.
  • "Mitochondrial replacement in human oocytes carrying pathogenic mitochondrial DNA mutations." Nature  In: , Vol. 540, No. 7632, 08.12.2016, p. 270-275.
  • "FANCD2 Facilitates Replication through Common Fragile Sites." Molecular Cell  In: , Vol. 64, No. 2, 20.10.2016, p. 388-404.
  • "Sponge Sampling with Fluorescent In Situ Hybridization as a Screening Tool for the Early Detection of Esophageal Cancer." Journal of Gastrointestinal Surgery  In: , 25.08.2016, p. 1-7.
  • "Cytokine overproduction and crosslinker hypersensitivity are unlinked in Fanconi anemia macrophages." Journal of Leukocyte Biology  In: , Vol. 99, No. 3, 01.03.2016, p. 455-465.
  • "MYD88 mutation analysis of a rare composite chronic lymphocyte leukemia and lymphoplasmacytic lymphoma by flow cytometry cell sorting." Annals of Hematology  In: , Vol. 94, No. 11, 22.11.2015, p. 1941-1944.
  • "The new equivocal : Changes to HER2 FISH results when applying the 2013 ASCO/CAP guidelines." American Journal of Clinical Pathology  In: , Vol. 144, No. 2, 01.08.2015, p. 253-262.
  • "Acquisition of relative interstrand crosslinker resistance and PARP inhibitor sensitivity in Fanconi anemia head and neck cancers." Clinical Cancer Research  In: , Vol. 21, No. 8, 15.04.2015, p. 1962-1972.
  • "Erratum to : Mosaic variegated aneuploidy in mouse BubR1 deficient embryos and pregnancy loss in human [Chromosome Research, 10.1007/s10577-014-9432-x]." Chromosome Research  In: , Vol. 22, No. 4, 06.12.2014.
  • "Comparison of chromosome breakage in non-mosaic and mosaic patients with Fanconi anemia, relatives, and patients with other inherited bone marrow failure syndromes." Cytogenetic and Genome Research  In: , Vol. 144, No. 1, 19.11.2014, p. 15-27.
  • "Aberrations of MYC are a common event in B-cell prolymphocytic leukemia." American Journal of Clinical Pathology  In: , Vol. 142, No. 3, 01.09.2014, p. 347-354.
  • "Bloom syndrome radials are predominantly non-homologous and are suppressed by phosphorylated BLM." Cytogenetic and Genome Research  In: , Vol. 144, No. 4, 24.04.2014, p. 255-263.
  • "Mosaic variegated aneuploidy in mouse BubR1 deficient embryos and pregnancy loss in human." Chromosome Research  In: , Vol. 22, No. 3, 2014, p. 375-392.
  • "Fancd2 and p21 function independently in maintaining the size of hematopoietic stem and progenitor cell pool in mice." Stem Cell Research  In: , Vol. 11, No. 2, 09.2013, p. 687-692.
  • "A molecular case report : Functional assay of tyrosine kinase inhibitors in cells from a patient's primary renal cell carcinoma." Cancer Biology and Therapy  In: , Vol. 14, No. 2, 02.2013, p. 95-99.
  • "MDM2 amplification and PI3KCA mutation in a case of sclerosing rhabdomyosarcoma." Sarcoma  In: , Vol. 2013, 520858, 2013.
  • "HER-2 gene amplification in human breast cancer without concurrent HER-2 over-expression." SpringerPlus  In: , Vol. 2, No. 1, 2013, p. 1-10.
  • "Patients with Fanconi anemia and AML have different cytogenetic clones than de novo cases of AML." Pediatric Blood and Cancer  In: , Vol. 59, No. 5, 11.2012, p. 922-924.
  • "In vivo selection of transplanted hepatocytes by pharmacological inhibition of fumarylacetoacetate hydrolase in wild-type mice." Molecular Therapy  In: , Vol. 20, No. 10, 10.2012, p. 1981-1987.
  • "Aneuploidy as a mechanism for stress-induced liver adaptation." Journal of Clinical Investigation  In: , Vol. 122, No. 9, 04.09.2012, p. 3307-3315.
  • "FANCL ubiquitinates β-catenin and enhances its nuclear function." Blood  In: , Vol. 120, No. 2, 12.07.2012, p. 323-334.
  • "Formaldehyde-induced genome instability is suppressed by an XPF-dependent pathway." DNA Repair  In: , Vol. 11, No. 3, 01.03.2012, p. 236-246.
  • "Frequent aneuploidy among normal human hepatocytes." Gastroenterology  In: , Vol. 142, No. 1, 01.2012, p. 25-28.
  • "Section E9 of the American College of Medical Genetics technical standards and guidelines : Fluorescence in situ hybridization." Genetics in Medicine  In: , Vol. 13, No. 7, 07.2011, p. 667-675.
  • "Fanconi anemia-like presentation in an infant with constitutional deletion of 21q including the RUNX1 gene." American Journal of Medical Genetics, Part A  In: , Vol. 155, No. 7, 07.2011, p. 1673-1679.
  • "GRB7 protein over-expression and clinical outcome in breast cancer." Breast Cancer Research and Treatment  In: , Vol. 127, No. 3, 06.2011, p. 659-669.
  • "Association of JAK2 mutation status and cytogenetic abnormalities in myeloproliferative neoplasms and myelodysplastic/myeloproliferative neoplasms." American Journal of Clinical Pathology  In: , Vol. 135, No. 5, 05.2011, p. 709-719.

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