Photo of Monika Davare, Ph.D.

Monika Davare Ph.D.

  •      (503) 494-5056
    • Assistant Professor of Pediatrics, Division of Hematology and Oncology School of Medicine
    • Program in Molecular and Cellular Biosciences School of Medicine
    • Cancer Biology Graduate Program School of Medicine

The Davare laboratory’s research goals are directed towards overcoming the therapeutic bottleneck in rare but aggressive pediatric and adult cancers. Oncogenomics-driven big data approaches effectively identify lead drug targets for cancer, but bottlenecks arise from a lack or slower pace of functionally testing, vetting and optimizing leads for therapeutic development. Using complementary in vitro and in vivo experimental model systems coupled with patient-derived genomic data, we have successfully identified driving kinase pathways and validated small-molecule inhibitor therapies for targeting distinct genomic subsets of glioblastoma, sarcoma, medulloblastoma and non-small cell lung cancer. We have active cross-institutional collaborations with clinical oncologists to facilitate transfer of our bench discoveries into clinical trials and as needed, validate clinical findings back at the bench. I combine my expertise and experience in the areas of kinase biology, cell surface receptors, and ion channel physiology with my background in molecular pharmacology to lead this translational research program.

Education

  • B.A., University of Maine (Zoology/Philosophy), Orono Maine 1995
  • Ph.D., University of Wisconsin-Madison (Molecular and Cellular Pharmacology), Madison Wisconsin 2000

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