Photo of Jonathan Q. Purnell, M.D.

Jonathan Q. Purnell M.D.

Dr. Purnell’s clinical interests include endocrinology, metabolism, obesity, diabetes and hyperlipidema. He received his medical degree from OHSU in 1986, and completed his residency training at the University of Vermont in Burlington. He completed his endocrinology fellowship at the University of Washington in Seattle. Dr. Purnell is board certified in internal medicine and in endocrinology.


  • M.D., Oregon Health & Science University, Portland Oregon 1986
  • Residency:

    • University of Vermont, Burlington, Vermont
  • Fellowship:

    • Endocrinology-University of Washington, Seattle

Memberships and associations

  • Internal medicine, 1989


  • "Plasma distribution and signaling activities of IGF-II precursors" Endocrinology March 2011
  • "Effect of intensive diabetes therapy on diabetic dyslipidemia" Diabetes Care  1997
  • "Bariatric surgery and diabetes who should be offered the option of remission?" JAMA - Journal of the American Medical Association April 15 2009
  • "Ghrelin concentrations in Prader-Willi syndrome (PWS) infants and children" Clinical Endocrinology December 2008
  • "Expectancy, Self-Efficacy, and Placebo Effect of a Sham Supplement for Weight Loss in Obese Adults" Journal of Evidence-Based Integrative Medicine  2014
  • "Fructose ingestion and cerebral, metabolic, and satiety responses" JAMA - Journal of the American Medical Association January 2 2013
  • "The central role of dietary fat, not carbohydrate, in the insulin resistance syndrome" Current Opinion in Lipidology  1997
  • "Change in postprandial substrate oxidation after a high-fructose meal is related to body mass index in healthy men" Nutrition Research June 2013
  • "Roles of leptin and ghrelin in the loss of body weight caused by a low fat, high carbohydrate diet" Journal of Clinical Endocrinology and Metabolism April 1 2003
  • "Circulating ghrelin levels are suppressed by meals and octreotide therapy in children with Prader-Willi syndrome" Journal of Clinical Endocrinology and Metabolism August 1 2003
  • "Cortisol production rates in subjects with suspected Cushing's syndrome" Journal of Clinical Endocrinology and Metabolism  2000
  • "Altered adipocyte structure and function in nutritionally programmed microswine offspring" Journal of Developmental Origins of Health and Disease June 2012
  • "Evidence-based nutrition principles and recommendations for the treatment and prevention of diabetes and related complications" Diabetes Care January 1 2003
  • "Reply to F Contaldo and F Pasanisi [3]" American Journal of Clinical Nutrition February 1 2006
  • "Relationship of family history of type 2 diabetes, hypoglycemia, and autoantibodies to weight gain and lipids with intensive and conventional therapy in the diabetes control and complications trial" Diabetes October 1 2003
  • "Serum ghrelin concentrations are increased in children with growth hormone insensitivity and decrease during long-term insulinlike growth factor-i treatment" Journal of Investigative Medicine January 2008
  • "A Preprandial Rise in Plasma Ghrelin Levels Suggests a Role in Meal Initiation in Humans" Diabetes August 2001
  • "Weight effect of current and experimental drugs for diabetes mellitus" Treatments in Endocrinology  2003
  • "Increased small dense LDL and intermediate-density lipoprotein with albuminuria in type 1 diabetes" Diabetes Care July 1999
  • "Serum ghrelin levels are inversely correlated with body mass index, age, and insulin concentrations in normal children and are markedly increased in Prader-Willi Syndrome" Journal of Clinical Endocrinology and Metabolism January 1 2003
  • "Levels of lipoprotein(a), apolipoprotein B, and lipoprotein cholesterol distribution in IDDM" Diabetes  1995
  • "Ghrelin in chronic kidney disease" Peritoneal Dialysis International January 2007
  • "Effect of amiloride on experimental gentamicin nephrotoxicity" Experimental Nephrology  1985
  • "American Diabetes Association Position Statement" Journal of the Academy of Nutrition and Dietetics  2002
  • "Erratum" Diabetes Care  1999
  • "Effects of a high-protein diet on regulation of phosphorus homeostasis" Journal of Clinical Endocrinology and Metabolism March 2013
  • "Plasma ghrelin levels after diet-induced weight loss or gastric bypass surgery" New England Journal of Medicine May 23 2002
  • "Reduced adipogenic gene expression in thigh adipose tissue precedes human immunodeficiency virus-associated lipoatrophy" Journal of Clinical Endocrinology and Metabolism March 2008
  • "Treating diabetes with surgery" JAMA - Journal of the American Medical Association  2013
  • "The effect of excess weight gain with intensive diabetes mellitus treatment on cardiovascular disease risk factors and atherosclerosis in type 1 diabetes mellitus" Circulation January 15 2013

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