Vascular Surgery Research

Gregory Moneta, M.D.

Dr. Greg Moneta

Title: Professor of Surgery

Research Focus: Non invasive vascular laboratory

Current projects:

  • Resolution of pediatric upper extremity DVT
  • Tibial Artery hemodynamics
  • Quantifying the Discrepancy Between ABI and Extent of Peripheral Artery Disease (PAD)

Select publications:

  1. Repella TL, Lopez O, Abraham CZ, Azarbal AF, Liem TK, Mitchell EL, Landry GJ, Moneta GL, Jung E.  Characterization of profunda femoris vein thrombosis.  J Vasc Surg Venous and Lym Dis 2018; 6:585-591.
  2. Wilson DG, Harris SK, Barton C, Crawford JD, Azarbal AF, Jung E, Mitchell EL, Landry GJ, Moneta GL.  Tibial artery duplex ultrasound peak systolic velocities may be an objective performance measure after above-knee endovascular therapy for arterial stenosis.  J Vasc Surg 2018; 68:481-6.
  3. Kronick MD, Chopra A, Swamy S, Brar V, Jung E, Abraham CZ, Liem TK, Landry GJ, Moneta GL.  Peak systolic velocity and color aliasing are important in development of duplex ultrasound criteria for external carotid artery stenosis.  J Vasc Surg 2020; 72:951-57. 
  4. Warner D, Summers S, Repella T, Landry GJ, Moneta GL.  Duplex ultrasound and clinical outcomes of pediatric lower extremity arterial thrombosis.  J Vasc Surg 2022;76;830-6.
  5. Nguyen K, Weber J, Samuel R, Moneta GL. Prospective study comparing the rate of deep venous thrombosis of complete and incomplete lower extremity venous duplex ultrasound examinations. J Vasc Surg: Venous and Lym Dis 2019; 7: 882-8.

OHSU Profile

Khanh Nguyen, M.D., M.C.R.

Dr. Khanh Nguyen

Title: Associate Professor of Surgery

Research Focus:  My primary research interests are to elucidate the basic mechanisms of vascular diseases, thrombosis, anticoagulation and vascular inflammation in order to further our fundamental understanding of diseases and contribute to knowledge base to translate findings to improve human health, particularly patients with vascular diseases.

Current projects:

The Nguyen Lab is conducting clinical trials studying vascular diseases such as deep vein and superficial vein thrombosis, venous diseases, post thrombotic syndrome, COVID-19 associated coagulopathy, wound healing, and peripheral arterial disease in addition to basic science studies investigating novel anticoagulants, venous thrombosis resolution, venous stenting and injury.

Select publications:

  1. Jordan KR, Wyatt CR, Fallon ME, Woltjer R, Neuwelt EA, Cheng Q, Gailani D, Lorentz C, Tucker EI, McCarty OJT, Hinds MT, Nguyen KP. Model Pharmacological reduction of coagulation factor XI reduces macrophage accumulation and accelerates deep vein thrombosis resolution in a mouse model of venous thrombosis. J Thromb Haemost. 2022 Sep;20(9):2035-2045.
  2. Nguyen KP, Hinds MT, Anderson DEJ. Vascular Graft Implantation Using a Bilateral End-to-Side Aortoiliac Preclinical Model. Methods Mol Biol. 2022;2375:203-215.
  3. Van Leuven SM, Mertzel ML, Ferdosian S, Samuel RJ, Landry GJ, Liem TK, Moneta GL, and Nguyen KP. Venous Conduits Have Superior Patency Compared with Prosthetic Grafts for Femorofemoral Bypass. J Vasc Surg Venous Lymphat Disord. 2021 Nov;9(6):1460-1466.
  4. Mukhopadhyay S, Antalis TM, Nguyen KP, Hoofnagle MH, Sarkar R. Myeloid p53 regulates macrophage polarization and venous thrombus resolution by inflammatory vascular remodeling in mice. Blood. 2017 Jun 15;129(24):3245-3255.
  5. Nguyen KP, McGilvray KC, Puttlitz CM, Mukhopadhyay S, Chabasse C, Sarkar R. Matrix Metalloproteinase 9 (MMP-9) Regulates Vein Wall Biomechanics in Murine Thrombus Resolution. Plos One. 2015 Sep 25;10(9):e0139145. 

OHSU Profile

Rhusheet Patel, M.D., M.S.

Dr. Rhusheet Patel

Title: Assistant Professor of Surgery

Research Focus: Limb salvage

Current projects:

  • Outcomes of pedal bypass
  • Lipoprotien(a) and its effect on limb salvage interventions

Select publications:

  1. Mandelbaum AD, Hadaya J, Ulloa JG, Patel R, McCallum JC, De Virgilio C, Benharash P. Impact of Frailty on Clinical Outcomes after Carotid Artery Revascularization. Ann Vasc Surg. 2021 Jul;74:111-121. 
  2. Janko M, Hubbard G, Woo K, Kashyap VS, Mitchell M, Murugesan A, Chen L, Gardner R, Baril D, Hacker RI, Szeberin Z, ElSayed R, Magee GA, Motta F, Zhou W, Lemmon G, Coleman D, Behrendt CA, Aziz F, Black JH, Tran K, Dao A, Shutze W, Garrett HE, De Caridi G, Patel R, Liapis CD, Geroulakos G, Kakisis J, Moulakakis K, Kakkos SK, Obara H, Wang G, Stoecker J, Rhéaume P, Davila V, Ravin R, DeMartino R, Milner R, Shalhub S, Jim J, Lee J, Dubuis C, Ricco JB, Coselli J, Lemaire S, Fatima J, Sanford J, Yoshida W, Schermerhorn ML, Menard M, Belkin M, Blackwood S, Conrad M, Wang L, Crofts S, Nixon T, Wu T, Chiesa R, Bose S, Turner J, Moore R, Smith J, Irshad A, Hsu J, Czerny M, Cullen J, Kahlberg A, Setacci C, Joh JH, Senneville E, Garrido P, Sarac TP, Rizzo A, Go MR, Bjorck M, Gavali H, Wanhainen A, D'Oria M, Lepidi S, Mastrorilli D, Veraldi G, Piazza M, Squizzato F, Beck A, St John R, Wishy A, Humphries M, Shah SK, Back M, Chung J, Lawrence PF, Bath J, Smeds MR. Contemporary Outcomes After Partial Resection of Infected Aortic Grafts. Ann Vasc Surg. 2021 Oct;76:202-210. 
  3. Patel R, Hanish S, Baril D, Woo K, Lawrence P. Contemporary management of lower extremity venous aneurysms. J Vasc Surg Venous Lymphat Disord. 2019 Nov;7(6):860-864. 
  4. Pantoja JL, Patel RP, Baril DT, Quinones-Baldrich W, Lawrence PF, Woo K. Caval Reconstruction with Undersized Ringed Graft after Resection of Inferior Vena Cava Leiomyosarcoma. Ann Vasc Surg. 2020 May;65:25-32.
  5. Ulloa JG, Gelabert HA, O'Connell JB, Patel R, Rigberg DA. Intravascular ultrasonography provides more sensitive detection of subclavian vein stenosis than venography in patients presenting with Paget-Schroetter syndrome. J Vasc Surg Venous Lymphat Disord. 2021 Sep;9(5):1145-1150.e1.

OHSU Profile

Sherene Shalhub, M.D., M.P.H.

Sherene Shalhub, M.D., M.P.H.

Title: Associate Professor of Surgery and Division Head of Vascular Surgery; Co-Director, OHSU Heart and Vascular Service Line

Research Focus: Aortic dissection; Ehlers-Danlos syndrome