Center for Policy and Research in Emergency Medicine (CPR-EM)

Overview

The OHSU Center for Policy and Research in Emergency Medicine's breakthrough research leads to new standards of care and a better understanding of important issues involving emergency medicine, disaster preparedness, and toxicology.

At the OHSU Center for Policy and Research in Emergency Medicine (CPR-EM), our mission consists of reducing inequities, including, but not limited to, those based on race, ethnicity, gender, sexual orientation, gender identity, immigration status, religion, and disability. In particular, we acknowledge the legacy of racism that is embedded in American society and institutions, and we are actively working to be catalysts of change to dismantle these harmful structures. Our commitment involves reflecting principles of equity across all functions of our organization, including in its culture, governance, hiring practices, salaries, research areas of focus, and the conduct of our research.  

Read the full CPR-EM Equity Operating Guidelines Beliefs and Values Statement

CPR-EM Research Team Zoom Meeting Photo
CPR-EM Team at our monthly center meeting - February 2021. Our first group photo op one year into the pandemic.

In the Media

ICECAP Research Team -Adventist Partnership Featured!

6/30/2021 - The CPR-EM, and Department of Emergency Medicine faculty and staff have worked hard over the past 2 years to create and foster a new relationship with Adventist Health.  They have proved to be extraordinary research partners.  Read more about this partnership here: https://news.ohsu.edu/2021/06/30/advancing-health-through-partnership 

Pacific NW Heatwave

6/29/21 - With the Northwest in the midst of a historic and unprecedented heat wave; Dr. Bory Kea took time to talk with our local news to discuss some of the challenges and concerns facing our local emergency departments.  Learn more here: https://www.kptv.com/news/oregons-heat-wave-turns-deadly-portland-metro-area-hospital-beds-at-critically-short-supply/article_a216eb04-d959-11eb-8630-cffe8211745e.html?block_id=994431

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Commuter spotlight: Tyne Riddick

Our colleague, Tyne, was featured in the "OHSU My Commute" newsletter in June!  It's a great story to put a smile on your face.

"My car broke down December 3, 2020 and I was left stranded. My partner and I had moved into the city to be closer to the hustle and bustle but I was still largely a car commuter despite the walkability of the city. When I began working at OHSU, I knew that I wanted to try alternative transportation, especially since my car was effectively a paper weight. Unfortunately, I could not afford a bike; so I walked. The hour walk was peaceful. It allowed me to listen to a podcast or two, finish a few audio books, and most importantly get some exercise. Luckily, I found Brilliant Bicycles Ambassador program. They gave me a free bike so that I could commute to and from school and work in exchange for some social media posts! I was happy to oblige! It is a sweet little forest green 3-speed commuter. So far, it has been the best thing to happen to me in 2021!"

-Tyne Riddick, Research Assistant

Learn more about the Brilliant Bicycles Program here: https://www.brilliant.co/pages/collegeunchained

6/1/2021- Congratulations to Dr. Bory Kea, Associate Professor, and Director of Clinical Trials for the Dept of Emergency Medicine, was awarded her first NIH R01 Grant, for her project titled: "Optimizing Stroke Prophylaxis of Acute Atrial Fibrillation with an Electronic Clinical Decision Support Tool: A Stepped-Wedge Cluster Randomized Trial Design", from the National Hearth Lung and Blood Institute (NHLBI). This is an important milestone in the research career of clinician-scientists, and represents an incredible amount of hard work, and perserverance.

OHSU CPR-EM ranked 10th in emergency medicine programs in the US in 2020

Spring 2021 - The Center for Policy and Research in Emergency Medicine was ranked 10th in Emergency Medical Research Rankings by the Blue Ridge Institute for Medical Research.  CPR-EM has ranked in the top 10 for 9 years running thanks to the excellence and hard work of our faculty and staff.  

C3PO - Clinical Trial of COVID-19 Convalescent Plasma of Outpatients

In August 2020, the OHSU ED began enrolling in the C3PO trial which is designed to confirm or refute the role of passive immunization as a safe and efficacious therapy in preventing the progression from mild to severe/critical COVID-19 illness and to understand the immunologic kinetics of anti-SARS-CoV-2 antibodies after passive immunization. 

This study concluded on 2/25/2021 after enrolling 511 subjects nationwide; 27 subjects were enrolled at OHSU.  

The results from this study are expected to be published in early summer, and we will provide a summary and link here once those results are available. 

OHSU C3PO Press release

Due to the COVID-19 Pandemic, some of the ED research projects listed below are currently suspended from enrolling subjects, however our research teams continue to engage in research activities that can be accomplished.

Craig Newgard

“Oregon Emergency Care Research Multidisciplinary Training Program”

Sponsor: National Heart, Lung, and Blood Institute (NHLBI), National Institute of Mental Health (NIMH), National Institute of Nursing Research (NINR) - 1K12HL133115

Award Dates: 08/15/16-06/30/21

Role: Principal Investigator

“The Value of Pediatric Readiness in the Emergency Care of Injured Children”

Sponsor: Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHHD) - 1R24HD085927

Award Dates: 09/30/17-06/30/22

Role: Principal Investigator

“A Multi-State Evaluation of Emergency Department Pediatric Readiness: Guideline Uptake and Association with Quality, Outcomes, and Cost”

Sponsor: Health Resources and Services Administration (HRSA) Maternal and Child Health Bureau - 1H34MC332430100

Award Dates: 09/01/19-08/31/23

Role: Principal Investigator

“Comparative Effectiveness of Trauma Center Care for Older Americans”

Sponsor: Brigham and Women's Hospital Inc (BWH) via National Institute on Aging (NIA) - 1R56AG048452-01A1

Award Dates: 09/30/17-08/31/19

Role: Site Principal Investigator / Co-Investigator

Additional emergency medicine research statistics can be found on the OHSU Research Expertise website. 
 

Esther Choo

“Implementation, Outcomes, and Cost of a Novel Medicaid Policy to Reduce
Opioids for Back Pain”

Sponsor: National Institute on Drug Abuse (NIDA) - 1R01DA044284

Award Dates: 08/15/18-05/31/23

Role: Principal Investigator

“Risk of Motor Vehicle Crashes from Cannabis Use in Emergency Department
Patients”

Sponsor: Insurance Institute for Highway Safety (IIHS)

Award Dates: 11/01/16-04/30/20

Role: Principal Investigator

“Virtual Coaching in Making Informed Choices on Elder Abuse/Neglect Self-Disclosure (VOICES)”

Sponsor: Yale University via NIA - 1R01AG060084

Award Dates: 09/01/18-08/31/22

Role: Site Principal Investigator / Co-Investigator

Matthew Hansen

“Improving the Safety and Efficacy of Out-of-Hospital Pediatric Airway Management”

Sponsor: National Heart, Lung, and Blood Institute - 1K23HL131440

Award Dates: 09/26/16-08/31/20

Role: Principal Investigator

“Charlotte, Houston, and Milwaukee Prehospital (CHaMP) Research Node”

Sponsor: Health Resources and Services Administration (HRSA) Bureau of Health Professions - 5H34MC26201

Award Dates: 09/01/17-08/31/20

Role: Site Principal Investigator / Co-Investigator

“The Charlotte, Houston, and Milwaukee Prehospital (CHaMP) Research Node”

Sponsor: Health Resources and Services Administration (HRSA) Maternal and Child Health Bureau - U03MC33154

Award Dates: 09/01/19-08/31/23

Role: Site Principal Investigator / Co-Investigator

Bory Kea

“Optimal Anticoagulation Strategies for Acute Atrial Fibrillation”

Sponsor: National Heart, Lung, and Blood Institute - 1K08HL140105

Award Dates: 12/15/17-11/30/20

Role: Principal Investigator

“Specimen Collection in the Emergency Department for the Assessment of Clinical Performance of the Siemens PBNP Assay”

Sponsor: Siemens Healthcare Diagnostics

Award Dates: 06/12/19-06/30/22

Role: Principal Investigator

“BUILD EXITO Y6”

Sponsor: EXITO Institutional Core

Award Dates: 11/01/19-06/30/20

Role: Principal Investigator

“VITROS® Immunodiagnostic Products hs Troponin I US Sample Collection Protocol”

Sponsor: Ortho-Clinical Diagnostics Inc

Award Dates: 06/18/18-06/30/21

Role: Principal Investigator

Brandon Maughan

“Sex-Based Differences in Risk Stratification and Diagnostic Imaging for Diagnosis of Pulmonary Embolism”

Sponsor: Oregon Emergency Care Research Multidisciplinary Training Program - National Heart, Lung, and Blood Institute - 5K12HL133115

Award Dates: 07/01/18-08/30/21

Role: Scholar

David Sheridan

“West Coast Consortium for Technology and Innovation in Pediatrics”

Sponsor: Children's Hospital Los Angeles (CHLA) via FDA - 1P50FD006425

Award Dates: 09/01/18-08/31/23

Role: Site Principal Investigator / Co-Investigator

“Solace: A Wearable Continuous Early Suicide Warning System for Adolescents”

Sponsor: Oregon Emergency Care Research Multidisciplinary Training Program

National Institute of Mental Health / National Heart, Lung, and Blood Institute - 5K12HL133115

Award Dates: 07/01/18-06/30/21

Role: Scholar

“SRA-19-145 ProMedix, Inc.”

Sponsor: ProMedix, Inc.

Award Dates: 08/01/19-07/31/20

Role: Principal Investigator

“Physiologic Parameters Related to Suicidality in Adolescent Mental Health”

Sponsor: Welch Allyn

Award Dates: 01/01/19-01/31/22

Role: Principal Investigator

Mohamud Daya

Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN) -
Network Clinical Center (Award Hub)”

Sponsor: National Institute of Neurological Disorders and Stroke (NINDS) - 1U24NS100657

Award Dates: 07/15/17-05/31/22

Role: Principal Investigator

“Characterizing Prehospital Delay and Outcomes in Patients Treated for Potential Acute Coronary Syndrome in the Emergency Department”

Sponsor: University of California, Los Angeles (UCLA) via National Heart, Lung, and Blood Institute - 1R21HL140277

Award Dates: 08/01/18-07/31/20

Role: Site Principal Investigator / Co-Investigator

Despite a pandemic, our emergency departments are emerging stronger and finding innovative ways to engage in research. Thank you—this work cannot be done without you. As research activities normalize, we hope to broaden the types of studies we pursue. We welcome feedback and your involvement to ensure high-quality studies that integrate into our clinical workflow.

- Bory Kea, MD, MCR, FACEP - Director of Clinical Trial, Department of Emergency Medicine

Current Newsletter

Interested in expanding your career to include Emergency Care Research? CPR-EM offers a variety of training programs for many experiential levels. Learn about all of our opportunities here, or click on a link below to be directed to that specific program. 

May/June 2021

June

A novel program to enhance pediatric emergency medicine training in Thailand. Burns BBailey J, Hartenstein M, Sullivan D, Burns E, Lin AChan D, Plainkum P, Techapaitoon S, Pandee U, Ma OJ. AEM Educ Train. 2021 May 2;5(3):e10596. doi: 10.1002/aet2.10596. eCollection 2021 Jul. PMID: 34124528

Adolescent Ingestions: Various Reasons and Medications. Sheridan DCHughes AHorowitz BZ. Pediatr Rev. 2021 Jun;42(6):279-289. doi: 10.1542/pir.2019-0310. PMID: 34074715 

Valuing Scholarship by Manuscript Reviewers: A Call to Action. Simpson D, Yarris LM, Artino AR Jr, Sullivan GM. J Grad Med Educ. 2021 Jun;13(3):313-315. doi: 10.4300/JGME-D-21-00418.1. Epub 2021 Jun 14. PMID: 34178251

Prehospital Airway Management: A Systematic Review. Carney N, Cheney T, Totten AM, Jungbauer R, Neth MR, Weeks C, Davis-O’Reilly C, Fu R, Yu Y, Chou R, Daya M. Rockville (MD): Agency for Healthcare Research and Quality (US); 2021 Jun. Report No.: 21-EHC023. PMID: 34181368 

CPR compression strategy 30:2 is difficult to adhere to, but has better survival than continuous chest compressions when done correctly. Schmicker RH, Nichol G, Kudenchuk P, Christenson J, Vaillancourt C, Wang HE, Aufderheide TP, Idris AH, Daya MR. Resuscitation. 2021 Jun 5;165:31-37. doi: 10.1016/j.resuscitation.2021.05.027. Online ahead of print. PMID: 34098033

Evaluation of Emergency Department Pediatric Readiness and Outcomes Among US Trauma Centers. Newgard CDLin A, Olson LM, Cook JNB, Gausche-Hill M, Kuppermann N, Goldhaber-Fiebert JD, Malveau S, Smith M, Dai M, Nathens AB, Glass NE, Jenkins PC, McConnell KJ, Remick KE, Hewes H, Mann NC; Pediatric Readiness Study Group. JAMA Pediatr. 2021 Jun 7:e211319. doi: 10.1001/jamapediatrics.2021.1319. Online ahead of print. PMID: 34096991

The MCAT was a Barrier to Diversity Long Before COVID-19. Cloutier RL, Bumsted T, Mejicano G. Acad Med. 2021 Jun 8. doi: 10.1097/ACM.0000000000004196. Online ahead of print. PMID: 34108378

Medical contraindications to combined hormonal contraceptive use among women using methods prescribed by a pharmacist. Rodriguez MI, Kaufman M, Manibusan B, Anderson L, McConnell KJ. Contraception. 2021 Jun 9:S0010-7824(21)00187-6. doi: 10.1016/j.contraception.2021.06.004. Online ahead of print. PMID: 34116068

Pediatric opioid-related emergency visits offer critical opportunities for opioid safety screening and planning. Love JS, Hughes AHendrickson RG. Am J Emerg Med. 2021 Jun 19:S0735-6757(21)00510-6. doi: 10.1016/j.ajem.2021.06.026. Online ahead of print. PMID: 34172306

Emergency medical services medical director and first responder attitudes regarding hands-on defibrillation. Adler DS, Jui J, Sahni R, Neth MRDaya MRLupton JR. Am J Emerg Med. 2021 Jun 26:S0735-6757(21)00530-1. doi: 10.1016/j.ajem.2021.06.046. Online ahead of print. PMID: 34218994

The 2021 Core Content of Medical Toxicology. Hendrickson RG, Bania TC, Baum CR, Greenberg MI, Joldersma KB, Keehbauch JN. J Med Toxicol. 2021 Jun 29. doi: 10.1007/s13181-021-00844-5. Online ahead of print. PMID: 34189709

Heart Rate Variability Duration: Expanding the Ability of Wearable Technology to Improve Outpatient Monitoring? Sheridan DC, Domingo KN, Dehart R, Baker SD. Front Psychiatry. 2021 Jun 15;12:682553. doi: 10.3389/fpsyt.2021.682553. eCollection 2021. PMID: 34211411 

Simultaneous Heart Rate Variability and Electroencephalographic Monitoring in Children in the Emergency Department. Piantino JA, Lin A, Luther M, Centeno LD, Williams CN, Newgard CD. J Child Adolesc Trauma. 2020 Jun 10;14(2):165-175. doi: 10.1007/s40653-020-00313-1. eCollection 2021 Jun. PMID: 33986903

May

Time from call to dispatch and out-of-hospital cardiac arrest outcomes. Daya MRLupton JR. Resuscitation. 2021 Jun;163:198-199. doi: 10.1016/j.resuscitation.2021.04.026. Epub 2021 May 13. PMID: 33965474 

The burden of cannabis-attributed pediatric and adult emergency department visits. Hendrickson RG, Dilley JA, Hedberg KM, Jeanne TL, Love JS, Thompson JAChoo EK. Acad Emerg Med. 2021 May 9. doi: 10.1111/acem.14275. Online ahead of print. PMID: 33966297

Assessment of the evolution of end-tidal carbon dioxide within chest compression pauses to detect restoration of spontaneous circulation. Gutiérrez JJ, Leturiondo M, Ruiz de Gauna S, Ruiz JM, Azcarate I, González-Otero DM, Urtusagasti JF, Russell JK, Daya MR. PLoS One. 2021 May 18;16(5):e0251511. doi: 10.1371/journal.pone.0251511. eCollection 2021. PMID: 34003839 

Medicaid Managed Care Network Adequacy Standards for Mental Health Care Access: Balancing Flexibility and Accountability. Zhu JM, Breslau J, McConnell KJ. JAMA Health Forum. 2021 May;2(5):e210280. doi: 10.1001/jamahealthforum.2021.0280. Epub 2021 May 14. PMID: 34124711 

Dana Zive

It is with a heavy heart that we announce the passing of our esteemed colleague,  Dana Zive, Sunday, September 30, 2018.

 Dana was the Director of the Oregon POLST Registry, Associate Director of the OHSU Center for Ethics in Health Care, and a Research Assistant Professor in the OHSU Department of Emergency Medicine and CPR-EM.  She earned her B.S. in Environmental Chemistry and Toxicology at the University of Nevada, Reno, and her M.P.H. in Public Health Education and Biostats/Epidemiology from San Jose State University.  Dana joined OHSU in 2004, and her areas of focus included end-of-life care and emergency care research. 

 Dana was integrally involved in many DEM research efforts, including the Resuscitation Outcomes Consortium (many out-of-hospital interventional trials in cardiac arrest and trauma) and the Physician Orders for Life-Sustaining Treatment Program (POLST).  She was key in developing and implementing the Oregon electronic POLST registry, including legislated state funding. Dana has been a fundamental member of CPREM throughout our years of building infrastructure and growth.  She had a true research mind and a passion for data. She was our colleague and friend and will be dearly missed. 

Dana is survived by her husband and daughter (Lola, 8).   If you have a story about Dana you would like to share with her family, please send your thoughts to cookjen@ohsu.edu