Center for Policy and Research in Emergency Medicine (CPR-EM)


The OHSU Center for Policy and Research in Emergency Medicine's breakthrough research leads to new standards of care and a better understanding of important issues involving emergency medicine, disaster preparedness, and toxicology.

At the OHSU Center for Policy and Research in Emergency Medicine (CPR-EM), our mission consists of reducing inequities, including, but not limited to, those based on race, ethnicity, gender, sexual orientation, gender identity, immigration status, religion, and disability. In particular, we acknowledge the legacy of racism that is embedded in American society and institutions, and we are actively working to be catalysts of change to dismantle these harmful structures. Our commitment involves reflecting principles of equity across all functions of our organization, including in its culture, governance, hiring practices, salaries, research areas of focus, and the conduct of our research.  

Read the full CPR-EM Equity Operating Guidelines Beliefs and Values Statement

In the Media

Dr. Esther Choo, Director of Equity and Inclusion in the Department of Emergency Medicine, OHSU

10/27/2020 - Congratulations to Dr. Esther Choo, who was appointed the first Director of Recruitment, Equity, and Inclusion (DREI) for the Department of Emergency Medicine.  In her new role, Dr. Choo will lead, coordinate, track, measure and assess the collective efforts of our team.  Dr. Choo will share her expertise to develop a diverse applicant pool when recruiting, and to ensure that the Department of Emergency Medicine (DEM) is one where a diverse faculty and staff can thrive and advance.  Dr. Choo will also promote continuous learning and education on diversity, anti-racism, unconscious bias, and equity.

The DEM and CPR-EM strive to support diversity, equity, and inclusion and foster a culture where everyone can operate at the top of their potential.

The CPR-EM faculty and staff are honored to have Dr. Choo as an integral member of our team, and are thrilled that Dr. Choo has been appointed to this new role within the department.  Dr. Choo has been and continues to be a strong advocate for equity, inclusion, and culture change, contributing to movements such as #TimesUpHealthCare.

C3PO - Clinical Trial of COVID-19 Convalescent Plasma of Outpatients

In August 2020, the OHSU ED began enrolling in the C3PO trial which is designed to confirm or refute the role of passive immunization as a safe and efficacious therapy in preventing the progression from mild to severe/critical COVID-19 illness and to understand the immunologic kinetics of anti-SARS-CoV-2 antibodies after passive immunization. 

What does that mean?  If you present to the OHSU ED, and are confirmed to have contracted COVID-19, you may be asked to participate in this trial.  Patients who participate will receive either Conalenscent Plaslma (CP) or a Placebo (saline and multi-vitamin infusion).  The study staff will talk with you before you are enrolled in this trial so you can decide if you would like to participate.  Participating in research is always voluntary, and the research team will give you the information you need to decide if you would like to participate. 

OHSU C3PO Press release

Survey of ED patients with COVID-like Symptoms

Drs. Newgard and Choo are leading a study to learn more about the clinical course and outcomes of patients with symptoms potentially consistent with a viral illness such as COVID-19, and to help guide health systems and emergency departments during the current pandemic.  If you visit the OHSU, Doernbecher, Tuality, or Columbia Memorial Hospital Emergency Departments and you are evaluated for COVID, or have any symptoms of a COVID-like illness, you may receive a request (via text or email) from the study team to complete a weekly survey for up to 30 days after your visit. To participate in this study, you DO NOT need to be COVID-19 positive, or even need to have been evaluated for COVID-19.   If you have questions about this study please contact

This study is being overseen by the OHSU IRB (#21302).  You may also contact the IRB at

View Study Information Sheet

Due to the COVID-19 Pandemic, some of the ED research projects listed below are currently suspended from enrolling subjects, however our research teams continue to engage in research activities that can be accomplished.

Craig Newgard

“Oregon Emergency Care Research Multidisciplinary Training Program”

Sponsor: National Heart, Lung, and Blood Institute (NHLBI), National Institute of Mental Health (NIMH), National Institute of Nursing Research (NINR) - 1K12HL133115

Award Dates: 08/15/16-06/30/21

Role: Principal Investigator

“The Value of Pediatric Readiness in the Emergency Care of Injured Children”

Sponsor: Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHHD) - 1R24HD085927

Award Dates: 09/30/17-06/30/22

Role: Principal Investigator

“A Multi-State Evaluation of Emergency Department Pediatric Readiness: Guideline Uptake and Association with Quality, Outcomes, and Cost”

Sponsor: Health Resources and Services Administration (HRSA) Maternal and Child Health Bureau - 1H34MC332430100

Award Dates: 09/01/19-08/31/23

Role: Principal Investigator

“Comparative Effectiveness of Trauma Center Care for Older Americans”

Sponsor: Brigham and Women's Hospital Inc (BWH) via National Institute on Aging (NIA) - 1R56AG048452-01A1

Award Dates: 09/30/17-08/31/19

Role: Site Principal Investigator / Co-Investigator

Additional emergency medicine research statistics can be found on the OHSU Research Expertise website. 

Esther Choo

“Implementation, Outcomes, and Cost of a Novel Medicaid Policy to Reduce
Opioids for Back Pain”

Sponsor: National Institute on Drug Abuse (NIDA) - 1R01DA044284

Award Dates: 08/15/18-05/31/23

Role: Principal Investigator

“Risk of Motor Vehicle Crashes from Cannabis Use in Emergency Department

Sponsor: Insurance Institute for Highway Safety (IIHS)

Award Dates: 11/01/16-04/30/20

Role: Principal Investigator

“Virtual Coaching in Making Informed Choices on Elder Abuse/Neglect Self-Disclosure (VOICES)”

Sponsor: Yale University via NIA - 1R01AG060084

Award Dates: 09/01/18-08/31/22

Role: Site Principal Investigator / Co-Investigator

Matthew Hansen

“Improving the Safety and Efficacy of Out-of-Hospital Pediatric Airway Management”

Sponsor: National Heart, Lung, and Blood Institute - 1K23HL131440

Award Dates: 09/26/16-08/31/20

Role: Principal Investigator

“Charlotte, Houston, and Milwaukee Prehospital (CHaMP) Research Node”

Sponsor: Health Resources and Services Administration (HRSA) Bureau of Health Professions - 5H34MC26201

Award Dates: 09/01/17-08/31/20

Role: Site Principal Investigator / Co-Investigator

“The Charlotte, Houston, and Milwaukee Prehospital (CHaMP) Research Node”

Sponsor: Health Resources and Services Administration (HRSA) Maternal and Child Health Bureau - U03MC33154

Award Dates: 09/01/19-08/31/23

Role: Site Principal Investigator / Co-Investigator

Bory Kea

“Optimal Anticoagulation Strategies for Acute Atrial Fibrillation”

Sponsor: National Heart, Lung, and Blood Institute - 1K08HL140105

Award Dates: 12/15/17-11/30/20

Role: Principal Investigator

“Specimen Collection in the Emergency Department for the Assessment of Clinical Performance of the Siemens PBNP Assay”

Sponsor: Siemens Healthcare Diagnostics

Award Dates: 06/12/19-06/30/22

Role: Principal Investigator


Sponsor: EXITO Institutional Core

Award Dates: 11/01/19-06/30/20

Role: Principal Investigator

“VITROS® Immunodiagnostic Products hs Troponin I US Sample Collection Protocol”

Sponsor: Ortho-Clinical Diagnostics Inc

Award Dates: 06/18/18-06/30/21

Role: Principal Investigator

Brandon Maughan

“Sex-Based Differences in Risk Stratification and Diagnostic Imaging for Diagnosis of Pulmonary Embolism”

Sponsor: Oregon Emergency Care Research Multidisciplinary Training Program - National Heart, Lung, and Blood Institute - 5K12HL133115

Award Dates: 07/01/18-08/30/21

Role: Scholar

David Sheridan

“West Coast Consortium for Technology and Innovation in Pediatrics”

Sponsor: Children's Hospital Los Angeles (CHLA) via FDA - 1P50FD006425

Award Dates: 09/01/18-08/31/23

Role: Site Principal Investigator / Co-Investigator

“Solace: A Wearable Continuous Early Suicide Warning System for Adolescents”

Sponsor: Oregon Emergency Care Research Multidisciplinary Training Program

National Institute of Mental Health / National Heart, Lung, and Blood Institute - 5K12HL133115

Award Dates: 07/01/18-06/30/21

Role: Scholar

“SRA-19-145 ProMedix, Inc.”

Sponsor: ProMedix, Inc.

Award Dates: 08/01/19-07/31/20

Role: Principal Investigator

“Physiologic Parameters Related to Suicidality in Adolescent Mental Health”

Sponsor: Welch Allyn

Award Dates: 01/01/19-01/31/22

Role: Principal Investigator

Mohamud Daya

Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN) -
Network Clinical Center (Award Hub)”

Sponsor: National Institute of Neurological Disorders and Stroke (NINDS) - 1U24NS100657

Award Dates: 07/15/17-05/31/22

Role: Principal Investigator

“Characterizing Prehospital Delay and Outcomes in Patients Treated for Potential Acute Coronary Syndrome in the Emergency Department”

Sponsor: University of California, Los Angeles (UCLA) via National Heart, Lung, and Blood Institute - 1R21HL140277

Award Dates: 08/01/18-07/31/20

Role: Site Principal Investigator / Co-Investigator

2020 has seemed like the longest year ever and a lifetime ago since we last saw each other's smiles. And yet, your support of one another, resiliency in the face of crises, and continued efforts to ensure humanism in medicine makes me proud to be a part of our ED team. We're in this together. Stay strong. Thank you to every member of our healthcare team.

- Bory Kea, MD, MCR, FACEP - Director of Clinical Trial, Department of Emergency Medicine

Current Newsletter

Interested in expanding your career to include Emergency Care Research? CPR-EM offers a variety of training programs for many experiential levels. Learn about all of our opportunities here, or click on a link below to be directed to that specific program. 

March 2021

Evidence-Based and Clinically Relevant Outcomes for Hemorrhage Control Trauma Trials. Holcomb JB, Moore EE, Sperry JL, Jansen JO, Schreiber MA, Del Junco DJ, Spinella PC, Sauaia A, Brohi K, Bulger EM, Cap AP, Hess JR, Jenkins D, Lewis RJ, Neal MD, Newgard C, Pati S, Pusateri AE, Rizoli S, Russell RT, Shackelford SA, Stein DM, Steiner ME, Wang H, Ward KR, Young P. Ann Surg. 2021 Mar 1;273(3):395-401. doi: 10.1097/SLA.0000000000004563. PMID: 33065652.

Housing Is an Essential Part of Health Care-"Treat 'Em and House 'Em". Barocas JA, Choo EK. JAMA Netw Open. 2021 Mar 1;4(3):e210635. doi: 10.1001/jamanetworkopen.2021.0635. PMID: 33651106 

Association of Medicare Mandatory Bundled Payment Program With the Receipt of Elective Hip and Knee Replacement in White, Black, and Hispanic Beneficiaries. Kim H, Meath THA, Quiñones AR, McConnell KJ, Ibrahim SA. JAMA Netw Open. 2021 Mar 1;4(3):e211772. doi: 10.1001/jamanetworkopen.2021.1772. PMID: 33749766

Comparing the Timeliness of Treatment in Younger vs. Older Patients with ST-Segment Elevation Myocardial Infarction: A Multi-Center Cohort Study. Bloos SM, Kaur K, Lang K, Gavin N, Mills AM, Baugh CW, Patterson BW, Podolsky SR, Salazar G, Mumma BE, Tanski M, Hadley K, Roumie C, McNaughton CD, Yiadom MYAB. J Emerg Med. 2021 Mar 3:S0736-4679(21)00087-1. doi: 10.1016/j.jemermed.2021.01.031. Online ahead of print. PMID: 33676790

Clinical and patient characteristics associated with severe outcome in diphenhydramine toxicity. Hughes ARLin AHendrickson RG; Toxicology Investigator’s Consortium (ToxIC). Clin Toxicol (Phila). 2021 Mar 5:1-8. doi: 10.1080/15563650.2021.1891244. Online ahead of print. PMID: 33666139

Chest stiffness dynamics in extended continuous compressions cardiopulmonary resuscitation. Russell JK, González-Otero DM, Leturiondo M, Ruiz de Gauna S, Ruiz JM, Daya MR. Resuscitation. 2021 Mar 8;162:198-204. doi: 10.1016/j.resuscitation.2021.03.001. Online ahead of print. PMID: 33705805

Focusing on recovery: Long-term health-related quality-of-life of out-of-hospital cardiac arrest survivors. Lupton JRDaya MR. Resuscitation. 2021 Mar 9:S0300-9572(21)00102-7. doi: 10.1016/j.resuscitation.2021.03.002. Online ahead of print. PMID: 33711399

Clinical prediction rule for SARS-CoV-2 infection from 116 U.Semergency departments 2-22-2021. Kline JA, Camargo CA Jr, Courtney DM, Kabrhel C, Nordenholz KE, Aufderheide T, Baugh JJ, Beiser DG, Bennett CL, Bledsoe J, Castillo E, Chisolm-Straker M, Goldberg EM, House H, House S, Jang T, Lim SC, Madsen TE, McCarthy DM, Meltzer A, Moore S, Newgard C, Pagenhardt J, Pettit KL, Pulia MS, Puskarich MA, Southerland LT, Sparks S, Turner-Lawrence D, Vrablik M, Wang A, Weekes AJ, Westafer L, Wilburn J. PLoS One. 2021 Mar 10;16(3):e0248438. doi: 10.1371/journal.pone.0248438. eCollection 2021. PMID: 33690722 

Outcomes of patients with OHCA of presumed cardiac etiology that did not achieve prehospital restoration of spontaneous circulation: The All-Japan Utstein Registry experience. Onoe A, Kajino K, Daya MR, Ong MEH, Nakamura F, Nakajima M, Takahashi H, Kishimoto M, Sakuramoto K, Muroya T, Ikegawa H, Kuwagata Y. Resuscitation. 2021 Mar 22;162:245-250. doi: 10.1016/j.resuscitation.2021.03.003. Online ahead of print. PMID: 33766662

An international survey of healthcare workers use of personal protective equipment during the early stages of the COVID-19 pandemic. Kea B, Johnson A, Lin A, Lapidus J, Cook JN, Choi C, Chang BP, Probst MA, Park J, Atzema C, Coll-Vinent B, Constantino G, Pozhidayeva D, Wilson A, Zell A, Hansen M. J Am Coll Emerg Physicians Open. 2021 Mar 26;2(2):e12392. doi: 10.1002/emp2.12392. eCollection 2021 Apr. PMID: 3381768

Bias in assessment: name, reframe, and check in. Fainstad TL, McClintock AH, Yarris LM. Clin Teach. 2021 Mar 30. doi: 10.1111/tct.13351. Online ahead of print. PMID: 33787001

Dana Zive

It is with a heavy heart that we announce the passing of our esteemed colleague,  Dana Zive, Sunday, September 30, 2018.

 Dana was the Director of the Oregon POLST Registry, Associate Director of the OHSU Center for Ethics in Health Care, and a Research Assistant Professor in the OHSU Department of Emergency Medicine and CPR-EM.  She earned her B.S. in Environmental Chemistry and Toxicology at the University of Nevada, Reno, and her M.P.H. in Public Health Education and Biostats/Epidemiology from San Jose State University.  Dana joined OHSU in 2004, and her areas of focus included end-of-life care and emergency care research. 

 Dana was integrally involved in many DEM research efforts, including the Resuscitation Outcomes Consortium (many out-of-hospital interventional trials in cardiac arrest and trauma) and the Physician Orders for Life-Sustaining Treatment Program (POLST).  She was key in developing and implementing the Oregon electronic POLST registry, including legislated state funding. Dana has been a fundamental member of CPREM throughout our years of building infrastructure and growth.  She had a true research mind and a passion for data. She was our colleague and friend and will be dearly missed. 

Dana is survived by her husband and daughter (Lola, 8).   If you have a story about Dana you would like to share with her family, please send your thoughts to