SIREN - About Us

About The Network

The Center for Policy and Research in Emergency Medicine (CPR-EM) at the OHSU Department of Emergency Medicine has been announced as Hub site of the newly formed nationwide Emergency Care Clinical Trials Network funded by the National Institutes of Health. Commonly known as SIREN, this network will support randomized trials of interventions for acutely ill patients in pre-hospital, emergency department, and intensive care unit settings. The OHSU Hub will coordinate enrollment at the following partner sites: Duke University Medical Center; Kaweah Delta Health Care District; Ohio State University Medical Center; University of Alabama Medical Center; University of Utah Medical Center; University of Wisconsin Medical Center; University of Rochester Medical Center; and Wake Forest Baptist Health.

"We're working closely with strong academic institutions. What we find may change medical practices across the country, and we know that academic medical center are committed to finding the best way of managing emergency health care." ~Dr. Sun

Mohamud Daya, M.D., a Professor of Emergency Medicine in the OHSU school of Medicine, is the grant recipient who will be coordinating the OHSU research hub-network for the five-year duration of the program.

The SIREN network is funded by the National Institute of Neurological Disorders and Stroke (NINDS) of the National Institutes of Health (NIH), under award number U24NS100657.

Read the OHSU Press Release

Mohamud Daya, M.D., M.S. - Principal Investigator

Dr. Daya is a Professor of Emergency Medicine in the DEM at OHSU and is board certified in Emergency Medicine with sub-specialty certification in EMS. He will serve as a SIREN MPI, and lead site recruitment, protocol implementation, and quality assurance efforts for all EMS trials. In addition to actively practicing emergency medicine, he also serve as the EMS medical director for multiple fire agencies in the Portland metro region and the Medical Director for the Washington County 911 Center. He has served as the PI for the Portland ROC site, Portland PAD Trial site and site Co-PI for the VOICE-3 study and REACT study. Daya is also a consultant from Oregon for the PNW Heart Rescue Project. He has received the EMS Medical Director of the year award for Oregon in 2009. In 2015, Daya ranked 49th nationally among EM principal investigators in total NIH funding. Currently he serves as a facilitator for the Pragmatic Airway in Resuscitation Trial (ROC PART) and is a co-investigator for the ROC TXA in TBI study.

Martin Schreiber, M.D., Co-Investigator

Dr. Schreiber is a Professor, the Chief of the Division of Trauma and Critical Care and Acute Surgery at OHSU, the Director of the Trauma Research Laboratory, and ROC and NETT Co-I. Dr. Schreiber will serve as Co-I and lead the implementation of trauma trials. He will assist in the development of additional trauma projects in association with the other Regional Clinical Centers

Craig Newgard, M.D., M.P.H., Co-Investigator

Dr. Newgard is a Professor in the Department of Emergency Medicine at OHSU, an emergency physician, previous EMS provider, Director of the OHSU Center for Policy and Research in Emergency Medicine , PI for the OHSU K12 Career Development Program in Emergency Care Research and Co-I of the Portland ROC site. Dr. Newgard will serve as Co-I and will contribute his content, methodologic, and logistic expertise to the OHSU SIREN hub

Miriam Treggiari, M.D., M.P.H., Ph.D., Co-Investigator

Dr. Treggiari is a Professor of the Department of Anesthesiology & Perioperative Medicine (APOM) and the Department of Public Health & Preventive Medicine, and Director of APOM Clinical Research. Dr. Treggiari will serve as a Co-I and will lead implementation of airway and critical care trials.

Denise Griffiths, C.C.R.P., Project Manager

Ms. Griffiths is OHSU DEM Research Manager and the Portland ROC site Project Manager. She has over 20 years of experience managing emergency care research studies, and she oversees the administration of all OHSU DEM research. Ms. Griffiths has expertise in grant preparation, regulatory processes including EFIC community consultation and public disclosure, budget preparation and reconciliation, subcontracts, data use agreements, data abstraction and entry, quality assurance, patient consent and follow up, personnel management, and writing group participation. She will support the management of SIREN trials.

Jenny Cook, G.C.P.H., Project Coordinator

Ms. Cook was Project Coordinator for the OHSU NETT hub and OHSU VOICES III site, and a former EMS provider. She has supported OHSU NETT and ROC teams with EFIC community consultation and public disclosure. She has extensive research experience conducting data abstraction, quality assurance, consenting patients and families, team training, and manuscript preparation, writing, and submission. Ms. Cook will continue similar roles as SIREN Project Coordinator.