Headshot photo of Zhenzhen Zhang, Ph.D., MPH, MMed

Zhenzhen Zhang, Ph.D., MPH, MMed

  • Assistant Professor of Division of Oncological Sciences, School of Medicine
  • OHSU Knight Cancer Institute, School of Medicine


Dr. Zhenzhen Zhang is a medical epidemiologist with research examining the effects of nutrition, diet, microbiome, and chronic disease outcomes.  Her research mainly focuses on identifying various risk factors and cancer outcomes with a particular interest in cancer prevention and investigating the molecular genetics and epigenetic modification mechanisms underlying these associations. She is also interested in diet and microbiome research and the life-course approach of cancer epidemiology. In addition, She is a Building Interdisciplinary Research Careers in Women's Health (BIRCWH) scholar sponsored by the National Institutes of Health and a fellow of the National Cancer Institute's Transdisciplinary Research on Energetics and Cancer (TREC).

Education and training

    • M.Med., 2004, Beijing University of Chinese Medicine
    • M.P.H., 2009, Louisiana State University Health Sciences Center
    • Ph.D., 2013, Michigan State University

Areas of interest

  • Cancer Prevention and Control Program, OHSU Knight Cancer Institute
  • Programmatic theme: Prevention and Risk Reduction, OHSU Knight Cancer Institute
  • Studying associations between various risk factors and cancer outcomes through working with SEER registries, with a particular interest in cancer prevention through molecular epigenetic modification mechanisms.
  • Epidemiology
  • Cancer Prevention
  • Nutrition and Chemoprevention
  • Microbiome

Honors and awards

  • National Cancer Institute (NCI)-funded Transdisciplinary Research on Energetics and Cancer (TREC) Training fellowship
  • American Association of Cancer Research Molecular Epidemiology Workshop
  • American Association of Cancer Research Susan G. Komen for the Cure® Scholar-in-Training Award
  • Blue Cross Blue Shield of Michigan Foundation Excellence in Research Award for Students Second Place
  • Delta Omega Honorary Society in Public Health


Selected publications

  • Z Zhang (Co-1st author), VL Irvin, MS Simon, RT Chlebowski, SW Luoh, AH Shadyab, JL Krok-Schoen, FK Tabung, L Qi, BJ Edwards, ML StefanickL, P Schedin, S Jindal. “Comparison of mortality among screening-detected breast cancers versus interval breast cancers in participants of Women's Health Initiative trials”. JAMA Network Open, 2020 Jun; 3(6): e207227.
  • Z Zhang, J Bien, T Mori, X Li, S Jindal, Y Liu, R Bergan A Way Forward for Cancer Chemoprevention: Using Multiple Factors to Refine Individual Risk. Accepted by Oncotarget 2019.
  • Z Zhang, D Jiang, C Wang, M Garzotto, R Kopp, B Wilmot, P Thuillier, A Dang, A Palma, PE Farris, J Shannon. Polymorphisms in Oxidative Stress Pathway Genes and Prostate Cancer Risk. Cancer Causes and Control. 2019 Oct 30. doi: 10.1007/s10552-019-01242-7.
  • Z Zhang, M Garzotto, EW Davis, M Mori, WA Stoller, PE Farris, CP Wong, LM Beaver, GV Thomas, DE Williams, RH Dashwood, DA Hendrix, E Ho, J Shannon. Sulforaphane Bioavailability and Chemopreventive Activity in Men Presenting for Biopsy of the Prostate Gland: a Randomized Controlled Trial. Nutr Cancer. 2019 Jun 1:1-14.
  • Z Zhang, R Bergan, J Shannon, C Slatore, G Bobe, Y Takata. The Role of Cruciferous Vegetables and Isothiocyanates for Lung Cancer Prevention: Current Status, Challenges and Future Research Directions. Mol Nutr Food Res. 2018 Sep: 62 (18).
  • Z Zhang, M Garzotto, TM Beer, P Thuillier, S Lieberman, M Mori, WA Stoller, PE Farris, J Shannon. Effect of ω-3 Fatty Acids and Catechins on Fatty Acid Synthase in the Prostate: a Randomized Controlled Trial. Nutrition and Cancer. 2016 Nov-Dec; 68 (8):1309-1319.
  • Z. Zhang, LL Atwell, PE Farris, E Ho, J Shannon. Associations between Cruciferous Vegetable Intake and Selected Biomarkers among Women Scheduled for Breast Biopsies. Public Health Nutr. 2016 May; 19 (7):1288-95.
  • Z Zhang, LL Atwell (Co-first author), E Ho, M Mori, PE Farris, JT Vetto, AM Naik, KY Oh, P Thuillier, J Shannon. Sulforaphane Bioavailability and Chemopreventive Activity in Women Scheduled for Breast Biopsy. Cancer Prev Res (Phila). 2015 Dec; 8(12):1184-91.
  • Z Zhang, G Hu, B Caballero, LJ Appel, L Chen. Habitual Coffee Consumption and Risk of Hypertension: A Meta-Analysis of Prospective Studies. Am J Clin Nutr, 2011 Jun; 93 (6): 1212-9.


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