Photo of Yali Jia, Ph.D.

Yali Jia Ph.D.

  • (503) 494-1053
    • Associate Professor of Ophthalmology School of Medicine
    • Associate Professor of Biomedical Engineering School of Medicine
    • Jennie P. Weeks Professor of Ophthalmology
    • Biomedical Engineering Graduate Program School of Medicine

Yali Jia, PhD is an Associate Professor of Ophthalmology and Biomedical Engineering, Jennie P. Weeks Professor of Ophthalmology and associate director of Center for Ophthalmic Optics & Lasers (www.coollab.net) at Oregon Health & Science University (OHSU). Dr. Jia earned her PhD in Biomedical Engineering from OHSU in 2010 under the guidance of Dr. Ruikang Wang. Dr. Jia completed her post-doctoral training with Dr. David Huang at Casey Eye Institute in 2013. Dr. Jia is known for her innovations in optical coherence tomographic angiography (OCTA) and the application to eye diseases. She developed split-spectrum amplitude-decorrelation angiography (SSADA), which is a major breakthrough that transitioned OCTA from a purely research technology to the clinic. Her original paper on this subject, published in 2012, has been cited 900 times. She was awarded 3 NIH research project grants that supported the initial works that demonstrated clinical applications of OCTA in retinal diseases. She is the technical leader in Casey Reading Center. Her OCTA reading software (COOL-ART) has been used by several large clinical studies and many international collaborators. She has published more than 100 peer-reviewed journal articles with over 6000 citations. She has co-edited 3 books.  Dr. Jia and her team are also pursuing research in other novel OCT technologies including the use of artificial intelligence to detect and classify retinal pathologies, spectroscopic OCT to measure tissue oxymetry, Doppler OCT to measure retinal blood flow, and the use of nanoparticles as OCT contrast agents.

Areas of interest

  • Optical Coherence Tomography and retinal imaging

Publications

  • "Noninvasive ocular angiography by optical coherence tomography"  January 1 2015
  • "In vivo optical imaging of revascularization after brain trauma in mice" Microvascular Research January 2011
  • "Macular perfusion in healthy chinese" Investigative Ophthalmology and Visual Science  2015
  • "Ultrahigh sensitive optical microangiography reveals depth-resolved microcirculation and its longitudinal response to prolonged ischemic event within skeletal muscles in mice" Journal of Biomedical Optics August 2011
  • "Optical coherence tomography angiography of peripapillary retinal blood flow response to hyperoxia" Investigative Ophthalmology and Visual Science  2015
  • "Spectral fractionation detection of gold nanorod contrast agents using optical coherence tomography" Optics Express February 23 2015
  • "En face Doppler total retinal blood flow measurement with 70 kHz spectral optical coherence tomography" Journal of Biomedical Optics June 1 2015
  • "Detecting blood flow response to stimulation of the human eye" BioMed Research International  2015
  • "Blood flow velocity quantification using splitspectrum amplitude-decorrelation angiography with optical coherence tomography" Biomedical Optics Express  2013
  • "Quantitative optical coherence tomography angiography of choroidal neovascularization in age-related macular degeneration" Ophthalmology  2014
  • "Potential of optical microangiography to monitor cerebral blood perfusion and vascular plasticity following traumatic brain injury in mice in vivo" Journal of Biomedical Optics  2009
  • "Depth-resolved optical imaging of hemodynamic response in mouse brain within microcirculatory beds"   2011
  • "Clinical applications of doppler OCT and OCT angiography"  January 1 2015
  • "Split-spectrum amplitude-decorrelation angiography with optical coherence tomography" Optics Express February 13 2012
  • "Detection of nonexudative choroidal neovascularization in age-related macular degeneration with optical coherence tomography angiography" Retina October 27 2015
  • "Optical coherence tomography angiography of optic nerve head and parafovea in multiple sclerosis" British Journal of Ophthalmology October 1 2014
  • "Quantitative OCT angiography of optic nerve head blood flow" Biomedical Optics Express December 1 2012
  • "High sensitive volumetric imaging of renal microcirculation in vivo using Ultrahigh Sensitive Optical Microangiography"   2011
  • "Responses of peripheral blood flow to acute hypoxia and hyperoxia as measured by optical microangiography" PLoS One October 25 2011
  • "Label-free in vivo optical micro-angiography imaging of cerebral capillary blood flow within meninges and cortex in mice with the skull left intact"   2011
  • "Label-free in vivo optical imaging of functional microcirculations within meninges and cortex in mice" Journal of Neuroscience Methods December 15 2010
  • "The study of effects of pore architecture in chitosan scaffolds on the fluid flow pattern by Doppler OCT"   2010
  • "Optical microangiography provides an ability to monitor responses of cerebral microcirculation to hypoxia and hyperoxia in mice" Journal of Biomedical Optics September 2011
  • "Label-free 3D optical microangiography imaging of functional vasa nervorum and peripheral microvascular tree in the hind limb of diabetic mice" Journal of Innovative Optical Health Sciences October 2010
  • "Parafoveal retinal vascular response to pattern visual stimulation assessed with OCT angiography" PLoS One December 2 2013
  • "Optical micro-angiography images structural and functional cerebral blood perfusion in mice with cranium left intact" Journal of Biophotonics January 2011
  • "Optical coherence tomography angiography features of diabetic retinopathy" Retina October 27 2015
  • "Optical coherence tomographic angiography of choroidal neovascularization associated with central serous chorioretinopathy" JAMA Ophthalmology October 1 2015
  • "Doppler optical coherence tomography imaging of local fluid flow and shear stress within microporous scaffolds" Journal of Biomedical Optics  2009
  • "Optical micro-angiography reveals depth-resolved muscular microcirculation"   2011

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