Victoria HJ Roberts, Ph.D.

  • Research Associate Professor, Oregon National Primate Research Center
  • Obstetrics and Gynecology, School of Medicine

Biography

Victoria Roberts, Ph.D., is a Research Associate Professor in the Division of Developmental and Reproductive Sciences at the Oregon National Primate Research Center. She works within a multidisciplinary team of scientists with an overall objective to understand the developing placenta. This area of research utilizes both in vivo and in vitro methods to understand placental function.

 Through the use of advanced imaging modalities such as ultrasound and magnetic resonance imaging (MRI), Dr. Roberts and colleagues have made in vivo assessments of placental hemodynamics in several nonhuman primate models of pregnancy complications, and in studies conducted in pregnant women. Gaining a better understanding of the placenta in utero may assist in the clinical management of pregnancies that are found to be at-risk for placental insufficiency.

 Furthermore, Dr. Roberts performs in vitro functional experiments in placental tissue post-delivery. When combined with structural assessments of the tissue, these in vitro studies provide insight as to the mechanisms of action that regulate function, and reveal the developmental changes that occur in adverse in utero conditions that underlie pregnancy complications.

Education and training

    • B.S., 1999, University of Reading
    • Ph.D., 2004, University of Manchester
  • Fellowship

    • Postdoctoral Fellow, University of Cincinnati, Cincinnati, OH, 2008

Memberships and associations:

  • Member, International Federation of Placenta Association, 2001-present
  • Member, Developmental Origins of Adult Disease Society, 2006-present
  • Member, Society for Reproductive Investigation, 2006-present

Areas of interest

  • Placental physiology, Developmental biology, In vitro model systems, In vivo imaging.

Honors and awards

  • 2016, SMFM Research Excellence Award, Society for Maternal Fetal Medicine, Atlanta
  • 2017, SMFM Research Excellence Award, Society for Maternal Fetal Medicine, Las Vegas
  • 2018, American Journal of Obstetrics & Gynecology, Research Excellence Award, Highly cited publication
  • 2019, American Journal of Obstetrics & Gynecology, Research Excellence Award, Highly cited publication

Publications

Selected publications

  • Roberts VHJ, Gaffney JE, Morgan TK, Frias AE. Placental adaptations in a nonhuman primate model of gestational protein restriction. J Dev Orig Health Dis. 2020 Dec 14:1-7. doi: 10.1017/S204017442000121X. Epub ahead of print. PMID: 33308351.
  • Roberts VH, Frias AE. Contrast-enhanced ultrasound for the assessment of placental development and function. Biotechniques. 2020 Nov;69(5):392-399. doi: 10.2144/btn-2020-0069. Epub 2020 Sep 4. PMID: 32883092; PMCID: PMC7669649. 
  • Roberts VH, Gaffney JE, Lewandowski KS, Schabel MC, Morgan TK, Frias AE. A standardized method for collection of human placenta samples in the age of functional magnetic resonance imaging. Biotechniques. 2019 Aug;67(2):45-49. doi: 10.2144/btn-2019-0029. Epub 2019 Jun 11. PMID: 31184493; PMCID: PMC7027198. 
  • Fayomi AP, Peters K, Sukhwani M, Valli-Pulaski H, Shetty G, Meistrich ML, Houser L, Robertson N, Roberts V, Ramsey C, Hanna C, Hennebold JD, Dobrinski I, Orwig KE. Autologous grafting of cryopreserved prepubertal rhesus testis produces sperm and offspring. Science. 2019 Mar 22;363(6433):1314-1319. doi: 10.1126/science.aav2914. Erratum in: Science. 2019 Apr 5;364(6435): PMID: 30898927; PMCID: PMC6598202
  • Sargent JA, Roberts V, Gaffney JE, Frias AE. Clarification and confocal imaging of the nonhuman primate placental micro-anatomy. Biotechniques. 2019 Feb;66(2):79-84. doi: 10.2144/btn-2018-0110. Epub 2018 Oct 29. PMID: 30370778; PMCID: PMC6521839. 
  • Hirsch AJ, Roberts VHJ, Grigsby PL, Haese N, Schabel MC, et al. Zika virus infection in pregnant rhesus macaques causes placental dysfunction and immunopathology. Nat Commun. 2018 Jan 17;9(1):
  • Roberts VHJ, Morgan TK, Bednarek P, Morita M, Burton GJ, Lo JO, Frias AE. Early first trimester uteroplacental flow and the progressive disintegration of spiral artery plugs: new insights from contrast-enhanced ultrasound and tissue histopathology. Hum Reprod. 2017 Dec 1;32(12):2382-2393. doi: 10.1093/humrep/dex301. PMID: 29136193; PMCID: PMC6251668.
  • Roberts VH, Lo JO, Salati JA, Lewandowski KS, Lindner JR, Morgan TK, Frias AE. Quantitative assessment of placental perfusion by contrast-enhanced ultrasound in macaques and human subjects. Am J Obstet Gynecol. 2016 Mar;214(3):369.e1-8. doi: 10.1016/j.ajog.2016.01.001. PMID: 26928151; PMCID: PMC4774055
  • Schabel MC, Roberts VHJ, Lo JO, Platt S, Grant KA, Frias AE, Kroenke CD. Functional imaging of the nonhuman primate Placenta with endogenous blood oxygen level-dependent contrast. Magn Reson Med. 2016 Nov;76(5):1551-1562. doi: 10.1002/mrm.26052. Epub 2015 Nov 24. PMID: 26599502; PMCID: PMC4879634
  • Frias AE, Schabel MC, Roberts VH, Tudorica A, Grigsby PL, Oh KY, Kroenke CD. Using dynamic contrast-enhanced MRI to quantitatively characterize maternal vascular organization in the primate placenta. Magn Reson Med. 2015 Apr;73(4):1570-8. doi: 10.1002/mrm.25264. Epub 2014 Apr 18. PMID: 24753177; PMCID: PMC4487918
  • Frias AE, Schabel MC, Roberts VH, Tudorica A, Grigsby PL, Oh KY, Kroenke CD. Using dynamic contrast-enhanced MRI to quantitatively characterize maternal vascular organization in the primate placenta. Magn Reson Med. 2015 Apr;73(4):1570-8. doi: 10.1002/mrm.25264. Epub 2014 Apr 18. PMID: 24753177; PMCID: PMC4487918

Publications

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