Photo of Trevor J. McGill, Ph.D.

Trevor J. McGill Ph.D.

  • (503) 466-3829
    • Research Assistant Professor of Ophthalmology School of Medicine

Dr. McGill received his Ph.D. from the University of Lethbridge in 2008 and subsequently joined the Casey Eye Institute at OHSU as a post doctoral fellow. In 2011, Dr. McGill joined the faculty at the Casey Eye Institute as Research Assistant Professor. Dr. McGill’s lab uses both rodent and nonhuman primate models of Retinitis Pigmentosa and Age-related Macular Degeneration to aid in the translation of cell-based and gene therapies for retinal degenerative disease into clinical trials.

Education

  • B.S., The University of Lethbridge, Lethbridge, Alberta Canada 2002
  • MSc, The University of Lethbridge, Lethbridge, Alberta Canada 2004
  • Ph.D., The University of Lethbridge, Lethbridge, Alberta Canada 2008

Publications

  • "Visual behavior" Neuromethods  2010
  • "Syngeneic schwann cell transplantation preserves vision in RCS rat without immunosuppression" Investigative Ophthalmology and Visual Science April 2007
  • "Quantification of spatial vision in the Royal College of Surgeons rat" Investigative Ophthalmology and Visual Science March 2004
  • "Spectral fractionation detection of gold nanorod contrast agents using optical coherence tomography" Optics Express February 23 2015
  • "Transplantation of human central nervous system stem cells - neuroprotection in retinal degeneration" European Journal of Neuroscience February 2012
  • "Measuring cone density in a Japanese macaque (Macaca fuscata) model of age-related macular degeneration with commercially available adaptive optics" Advances in Experimental Medicine and Biology  2014
  • "Anatomical, physiological, and behavioral analysis of rodent vision"   2011
  • "Discordant anatomical, electrophysiological, and visual behavioral profiles of retinal degeneration in rat models of retinal degenerative disease" Investigative Ophthalmology and Visual Science September 2012
  • "Preservation of vision following cell-based therapies in a model of retinal degenerative disease" Vision Research October 2004
  • "Human adult bone marrow-derived somatic cells rescue vision in a rodent model of retinal degeneration" Experimental Eye Research September 2010
  • "Optomotor and immunohistochemical changes in the juvenile S334ter rat" Experimental Eye Research November 2012
  • "Independent visual threshold measurements in the two eyes of freely moving rats and mice using a virtual-reality optokinetic system" Visual Neuroscience September 2005
  • "Phagocytosis of photoreceptor outer segments by transplanted human neural stem cells as a neuroprotective mechanism in retinal degeneration" Investigative Ophthalmology and Visual Science September 17 2013
  • "Intraocular CNTF reduces vision in normal rats in a dose-dependent manner" Investigative Ophthalmology and Visual Science December 2007
  • "Elevated fundus autofluorescence in monkeys deficient in lutein, zeaxanthin, and omega-3 fatty acids" Investigative Ophthalmology and Visual Science March 1 2016
  • "Erratum" Human gene therapy. Clinical development December 1 2015
  • "SUBRETINAL CELL-BASED THERAPY" Retina January 16 2017
  • "Long-term characterization of retinal degeneration in royal college of surgeons rats using spectral-domain optical coherence tomography" Investigative Ophthalmology and Visual Science March 1 2017
  • "Allogeneic iPSC-derived RPE cell graft failure following transplantation into the subretinal space in nonhuman primates" Investigative Ophthalmology and Visual Science March 1 2018
  • "Cell transplantation for retinal degeneration"  January 1 2018
  • "Discovery of a CLN7 model of Batten disease in non-human primates" Neurobiology of Disease November 1 2018
  • "Clinical-grade stem cell-derived retinal pigment epithelium patch rescues retinal degeneration in rodents and pigs" Science Translational Medicine January 16 2019
  • "New MiniPromoter Ple345 (NEFL) drives strong and specific expression in retinal ganglion cells of mouse and primate retina" Human Gene Therapy March 1 2019
  • "Subretinal transplantation of human central nervous system stem cells stimulates controlled proliferation of endogenous retinal pigment epithelium" Translational Vision Science and Technology May 1 2019

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