Sunwen Chou, M.D.

  • Professor Emeritus of Medicine, Division of Infectious Diseases, School of Medicine

Education and training

    • B.A., 1973, Dartmouth College
    • M.D., 1977, UCLA School of Medicine

  • Residency

    • Medicine - UCLA Hospital - (1977-1980)

  • Fellowship

    • Infectious diseases - Stanford University - (1980-1983)

Areas of interest

  • Human cytomegalovirus antivirals and drug resistance

Publications

Elsevier pure profile

Selected publications

  • Chou S, Marousek GI. Accelerated evolution of maribavir resistance in a cytomegalovirus exonuclease domain II mutant. J Virol 2008;82:246-53.
  • Strasfeld S, Lee I, Tatarowicz W, Villano S, Chou S. Virologic characterization of multi-drug-resistant cytomegalovirus infection in two transplant recipients treated with maribavir. J Infect Dis 2010;202:104-8.
  • Chou S, Ercolani RJ, Marousek G, Bowlin T. Cytomegalovirus UL97 kinase catalytic domain mutations that confer multi-drug resistance. Antimicrob Agents Chemother 2013;57: 3375-9.
  • Chou S, Boivin G, Ives J, Elston R. Phenotypic evaluation of previously uncharacterized cytomegalovirus DNA polymerase sequence variants detected in a valganciclovir treatment trial. J Infect Dis 2014;209:1219-26.
  • Webel R, Hakki M, Prichard MN, Rawlinson WD, Marschall M, Chou S. Differential properties of cytomegalovirus pUL97 kinase isoforms affect viral replication and maribavir susceptibility. J Virol 2014;88:4776-85.
  • Chou S, Ercolani RJ, Sahoo MK, Lefterova MI, Strasfeld LM, Pinsky BA. Improved detection of emerging drug-resistant mutant cytomegalovirus subpopulations by deep sequencing. Antimicrob Agents Chemother 2014;58:4697-4702.
  • Chou S. Rapid in vitro evolution of human cytomegalovirus UL56 mutations that confer letermovir resistance. Antimicrob Agents Chemother 2015;59:6588-93.
  • Chou S, Ercolani RJ, Lanier ER. Novel cytomegalovirus UL54 DNA polymerase gene mutations selected in vitro that confer brincidofovir resistance. Antimicrob Agents Chemother 2016;60:3845-8.
  • Chou S. Foscarnet resistance mutations mapping to atypical domains of the cytomegalovirus DNA polymerase gene. Antiviral Res 2017;138:57-60.
  • Chou S, Ercolani RJ, Vanarsdall AL. Differentiated levels of ganciclovir resistance conferred by mutations at codons 591-603 of the cytomegalovirus UL97 kinase gene. J Clin Microbiol 2017;55:2098-2104.