Dr. Aicher has a long-standing interest in primary afferent sensory systems and how sensory information leads to physiological and behavioral changes in the organism. She has done extensive work using various histological methods and is recongized for her anatomical studies of neural circuits. Her training in psychology and behavior informs her approach to seeking understanding of how neural circuits modulate behavior. The lab focuses on the cellular mechanism underlying normal and pathophysiological functions in pain and autonomic reflex pathways, as well as neural substrates of addiction. These studies use a variety of techniques including tract tracing, dual labeling immunocytochemistry, electron microscopy, behavioral and physiological measurements, and single neuron activity in the brain. Dr. Aicher also collaborates extensively with colleagues at OHSU within her department, across OHSU, the US and in Australia.
The Aicher lab is currently funded by grants from the National Institute of Neurological Disorders and Stroke; the National Institute on Drug Abuse; and the National Eye Institute
Grant #s: P30 NS061800 (Aicher, PI); R01 DA040965 (Sorg, PI); R41 EY030804 (Aicher, PI)Read more
Areas of interest
- Central autonomic reflex pathways; pain pathways; neuroanatomy
- Ph.D., University of Iowa, Iowa City Iowa United States 1989
Memberships and associations
- Editorial Board, The Journal of Comparative Neurology
- Editorial Board, Journal of Chemical Neuroanatomy
Hegarty DM, David LL, Aicher SA (2018) Lacrimal gland denervation alters tear protein composition and impairs ipsilateral eye closure and nociception. Invest Ophthalmol Vis Sci, 59: 5217-5224. Hegarty DM, Hermes SM, Morgan MM, Aicher SA (2018) Acute hyperalgesia and delayed dry eye after corneal abrasion injury. Pain Reports June 20; 3(4): e664. Winters BL, Gregoriou GC, Kissiwaa SA, Wells OA, Medagoda DI, Hermes SM, Burford NT, Alt A, Aicher SA, Bagley EE (2017) Endogenous opioids regulate moment-to-moment neuronal communication and excitability. Nature Commun 8:14611.