Photo of Steven W. Johnson, M.D., Ph.D.

Steven W. Johnson M.D., Ph.D.

    • Professor Emeritus of Neurology School of Medicine
    • Neuroscience Graduate Program School of Medicine

Dr. Johnson received his MD from University of Colorado Health Sciences University and his Ph.D. in pharmacology from Oregon Health & Science University (OHSU). Dr. Johnson completed his neurology residency at OHSU in 1989.

Dr. Johnson joined the OHSU Movement Disorder faculty in 1990 and is now a Professor of Neurology. He maintains an active basic science program that investigates changes in brain neurochemistry that occur in animal models of Parkinson's disease. He is widely known nationally and internationally for his work that has characterized neuropharmacological actions of dopamine in the brain.

Dr. Johnson is also an expert clinician and has expertise in the clinical diagnosis and treatment of Parkinson's disease and other movement disorders.

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  • Residency:

    • Medicine, St. Lukes Presbyterian Hospital, Denver, CO
  • Fellowship:

    • Neuropharmacology-Oregon Health &Science University, Portland

Publications

  • "Correlation of Purkinje neuron depression and hypnotic effects of ethanol in inbred strains of rats" Alcoholism: Clinical and Experimental Research  1985
  • "Presynaptic inhibition of synaptic transmission by adenosine in rat subthalamic nucleus in vitro" Neuroscience January 15 2003
  • "Persistant effects of amphetamine on cerebellar Purkinje neurons following chronic administration" Brain Research September 16 1982
  • "Evaluation of the aesthetics of physical methods of euthanasia of anesthetized rats" Journal of the American Association for Laboratory Animal Science September 2011
  • "Group II metabotropic glutamate receptor modulation of excitatory transmission in rat subthalamic nucleus" Journal of Physiology December 1 2003
  • "Actions of 5-hydroxytryptamine on ventral tegmental area neurons of the rat in vitro" Brain Research August 22 1994
  • "Group i mGluRs evoke K-ATP current by intracellular Ca2+ mobilization in rat subthalamus neurons" Journal of Pharmacology and Experimental Therapeutics April 2013
  • "GDNF acutely modulates excitability and A-type K+ channels in midbrain dopaminergic neurons" Nature Neuroscience  2001
  • "Dual modulation of gabaergic transmission by metabotropic glutamate receptors in rat ventral tegmental area" Neuroscience June 27 2003
  • "Dopamine-mediated actions of ephedrine in the rat substantia nigra" Brain Research January 19 2006
  • "Recent advances in the pharmacology of quaternary salts of bicuculline" Trends in Pharmacological Sciences July 1 1999
  • "Metabolism, tissue distribution, and elimination kinetics of phenytoin in the frog" Drug Metabolism and Disposition  1982
  • "Structure-activity relationships of phencyclidine derivatives in rat cerebellum" Pharmacology Biochemistry and Behavior  1986
  • "Presynaptic GABA(B) and adenosine A1 receptors regulate synaptic transmission to rat substantia nigra reticulata neurones" Journal of Physiology November 15 1997
  • "Bromide and phenytoin elimination in the bullfrog" Federation Proceedings  1978
  • "Rotenone reduces Mg2+-dependent block of NMDA currents in substantia nigra dopamine neurons" NeuroToxicology March 2009
  • "Sigma ligands, but not N-methyl-D-aspartate antagonists, reduce levodopa-induced dyskinesias" NeuroReport January 2008
  • "Pharmacological identification of inward current evoked by dopamine in rat subthalamic neurons in vitro" Neuropharmacology  2002
  • "Metabotropic glutamate and muscarinic cholinergic receptor-mediated preferential inhibition of N-methyl-D-aspartate component of transmissions in rat ventral tegmental area" Neuroscience February 28 2003
  • "Dopamine oxidation facilitates rotenone-dependent potentiation of N-methyl-d-aspartate currents in rat substantia nigra dopamine neurons" Neuroscience November 10 2011
  • "Sodium pump evokes high density pump currents in rat midbrain dopamine neurons" Journal of Physiology October 15 1998
  • "Effects of d-amphetamine withdrawal in rats and man." American Journal of Psychiatry July 1983
  • "Alpha1-adrenergic effects on dopamine neurons recorded intracellularly in the rat midbrain slice" European Journal of Neuroscience  1995
  • "Rotenone potentiates NMDA currents in substantia nigra dopamine neurons" Neuroscience Letters June 27 2007
  • "Phenytoin antagonism of electrically induced maximal seizures in frogs and mice and effects on central nervous system levels of adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate" Journal of Pharmacology and Experimental Therapeutics  1982
  • "Gamma-aminobutyric acidB receptor activation suppresses stimulus-evoked burst firing in rat substantia nigra reticulata neurons" NeuroReport January 4 2012
  • "Opioids excite dopamine neurons by hyperpolarization of local interneurons" Journal of Neuroscience  1992
  • "Norepinephrine-dependent and independent mechanisms of persistent effects of amphetamine in rat cerebellum" Life Sciences June 24 1985
  • "Two types of neurone in the rat ventral tegmental area and their synaptic inputs" Journal of Physiology  1992
  • "Multiple mechanisms underlie burst firing in rat midbrain dopamine neurons in vitro" Brain Research September 3 2004

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