Photo of Soren Impey, Ph.D.

Soren Impey Ph.D.

  • (503) 494-7540
    • Associate Professor of Pediatrics School of Medicine
    • Cell and Developmental Biology Graduate Program School of Medicine
    • Cancer Biology Graduate Program School of Medicine
    • Program in Molecular and Cellular Biosciences School of Medicine

1991-1998 Ph.D., University of Washington1998-2000 Postdoctoral Fellow, University of Washington2000-2006 Postdoctoral Fellow, Vollum Institute, OHSU2006-present Assistant Professor, Oregon Stem Cell Center, Dept. of Cell and Developmental biology, OHSU


  • Ph.D., University of Washington, Seattle Washington 1998

Memberships and associations

  • Cell &Developmental Biology Neuroscience Graduate Program Program in Molecular &Cellular Biosciences


  • "MicroRNA regulation of neural stem cells and neurogenesis" Journal of Neuroscience November 10 2010
  • "Mitogen- and stress-activated kinases regulate progenitor cell proliferation and neuron development in the adult dentate gyrus" Journal of Neurochemistry December 2012
  • "Activity-dependent neuroprotection and cAMP response element-binding protein (CREB)" Journal of Neuroscience February 2 2005
  • "Hippocampal CRE-mediated gene expression is required for contextual memory formation" Nature Neuroscience November 1 2002
  • "Cell-type-specific binding of the transcription factor CREB to the cAMP-response element" Proceedings of the National Academy of Sciences of the United States of America September 14 2004
  • "cAMP response element-mediated gene expression in transgenic reporter gene mouse strain" ImmunoMethods  2001
  • "Cre-mediated gene transcription in neocortical neuronal plasticity during the developmental critical period" Neuron January 1999
  • "Transgenic miR132 alters neuronal spine density and impairs novel object recognition memory" PLoS One  2010
  • "Regulation of Axonal Extension and Growth Cone Motility by Calmodulin-Dependent Protein Kinase I" Journal of Neuroscience April 14 2004
  • "Defining the CREB regulon" Cell December 29 2004
  • "Ca2+ inhibition of type III adenylyl cyclase in vivo" Journal of Biological Chemistry September 15 1995
  • "Pin1 Regulates the Dynamics of c-Myc DNA Binding To Facilitate Target Gene Regulation and Oncogenesis" Molecular and Cellular Biology August 2013
  • "Hippocampal neurotoxicity of Δ9-tetrahydrocannabinol" Journal of Neuroscience July 15 1998
  • "Epigenetic mechanisms and gene networks in the nervous system" Journal of Neuroscience November 9 2005
  • "A Histone Deacetylase Regulates Addiction" Neuron November 8 2007
  • "Homeostatic regulation of MeCP2 expression by a CREB-induced microRNA" Nature Neuroscience December 2007
  • "Patterned vision causes CRE-mediated gene expression in the visual cortex through PKA and ERK" Journal of Neuroscience August 6 2003
  • "Circadian regulation of cAMP response element-mediated gene expression in the suprachiasmatic nuclei" Journal of Biological Chemistry June 18 1999
  • "Phosphorylation and inhibition of olfactory adenylyl cyclase by CaM kinase II in neurons" Neuron September 1998
  • "An activity-induced microRNA controls dendritic spine formation by regulating Rac1-PAK signaling" Molecular and Cellular Neuroscience January 2010
  • "A new binding motif for the transcriptional repressor REST uncovers large gene networks devoted to neuronal functions" Journal of Neuroscience June 20 2007
  • "Leptin induces hippocampal synaptogenesis via CREB-regulated MicroRNA-132 suppression of p250GAP" Molecular Endocrinology  2014
  • "Role reversal" Current Opinion in Neurobiology October 2005
  • "The environmental neurotoxicant PCB 95 promotes synaptogenesis via ryanodine receptor-dependent miR132 upregulation" Journal of Neuroscience  2014
  • "Regulation and immunohistochemical localization of βγ-stimulated adenylyl cyclases in mouse hippocampus" Journal of Neuroscience January 1 1999
  • "Cooperative Mechanism of Transcriptional Activation by a Cyclic AMP-response Element Modulator α Mutant Containing a Motif for Constitutive Binding to CREB-binding Protein" Journal of Biological Chemistry February 2 2001
  • "cAMP response element-mediated gene transcription is upregulated by chronic antidepressant treatment" Journal of Neuroscience June 1 2000
  • "Erratum" Proceedings of the National Academy of Sciences of the United States of America January 17 2006
  • "A Genome-Wide Screen of CREB Occupancy Identifies the RhoA Inhibitors Par6C and Rnd3 as Regulators of BDNF-Induced Synaptogenesis" PLoS One June 6 2013
  • "Targeting inhibitors of the tumor suppressor PP2A for the treatment of pancreatic cancer" Molecular Cancer Research  2014

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