Dr. Rachael Wolters is a Research Assistant Professor in the Department of Pathobiology and Immunology. A dedicated veterinary scientist, she specializes in humoral viral immunity with particular interests in antibody discovery, vaccine development, pathogen-host interactions, and in vivo models for drug development.

Dr. Wolters earned her DVM from the University of Tennessee, where she conducted research on microbial pathogenesis and antibiotic resistance mechanisms in Staphylococcus pseudintermedius. She then pursued her Ph.D. at Vanderbilt University under the mentorship of Dr. James Crowe, focusing on monoclonal antibody development for respiratory viruses. Over the course of her career, she has authored numerous peer-reviewed publications and received several honors, including the Richard Armstrong Prize for Research Excellence from the Vanderbilt Institute of Chemical Biology. She was also awarded an NIH K01 grant, recognizing her promise as an early-career research veterinarian.

At the Oregon National Primate Research Center (ONPRC), Dr. Wolters collaborates with Dr. Ann Hessell to lead an interdisciplinary research group investigating the mechanisms of antiviral monoclonal therapies in rhesus macaque models. Employing advanced in vivo imaging, tissue characterization via immunohistochemistry and in situ hybridization, and a suite of classic virological methods, their team rigorously evaluates novel therapeutic candidates—particularly those targeting pediatric diseases, such as mother-to-child transmission of HIV. Dr. Wolters also explores AI-guided digital pathology, de novo drug design, and the development of alternatives to traditional animal models.

Beyond her research, Dr. Wolters is committed to fostering a vibrant, safe, and diverse scientific community. She serves as co-chair of the OHSU West Campus Employee Events Committee and is an active member of the Don Picknell Award committee. Driven by her passion for mentorship and collaboration, Dr. Wolters strives to inspire innovation and cultivate the next generation of immunology leaders.