Photo of Philip Streeter, Ph.D.

Philip Streeter Ph.D.

The long-term research goals of the Streeter laboratory are to contribute to the emerging fields of tissue engineering/repair and the development of tools for cancer diagnosis.  Areas of research focus are beta cell replacement therapies for the treatment of diabetes, the identification of lung progenitor cell populations involved in lung repair, and in the diagnosis of pancreatic cancer.

Publications

  • "Effects of erythropoietin receptor activity on angiogenesis, tubular injury, and fibrosis in acute kidney injury : A “U-shaped” relationship." American Journal of Physiology - Renal Physiology  In: , Vol. 314, No. 4, 01.04.2018, p. F501-F516.
  • "Humanised recombinant antibody fragments bind human pancreatic islet cells." Journal of Immunological Methods  In: , 01.01.2018.
  • "Monoclonal Antibodies Reveal Dynamic Plasticity Between Lgr5- and Bmi1-Expressing Intestinal Cell Populations." CMGH  In: , Vol. 6, No. 1, 01.01.2018, p. 79-96.
  • "Glycoprotein 2 is a specific cell surface marker of human pancreatic progenitors." Nature Communications  In: , Vol. 8, No. 1, 331, 01.12.2017.
  • "Human islets contain four distinct subtypes of β cells." Nature Communications  In: , Vol. 7, 11756, 11.07.2016.
  • "New markers for tracking endoderm induction and hepatocyte differentiation from human pluripotent stem cells." Development (Cambridge)  In: , Vol. 142, No. 24, 15.12.2015, p. 4253-4265.
  • "Novel surface markers directed against adult human gallbladder." Stem Cell Research  In: , Vol. 15, No. 1, 01.07.2015, p. 172-181.
  • "Abnormal development of peripheral lymphoid organs in mice deficient in lymphotoxin." Journal of Immunology  In: , Vol. 192, No. 5, 01.03.2014, p. 2007-2014.
  • "The organoid-initiating cells in mouse pancreas and liver are phenotypically and functionally similar." Stem Cell Research  In: , Vol. 13, No. 2, 2014, p. 275-283.
  • "Pillars article : Abnormal development of peripheral lymphoid organs in mice deficient in lymphotoxin. Science. 1994. 264: 703-707." Journal of Immunology  In: , Vol. 192, No. 5, 2014, p. 2010-2014.
  • "Erratum : Transcriptomes of the major human pancreatic cell types (Diabetologia DOI: 10.1007/s00125-011-2283-5)." Diabetologia  In: , Vol. 56, No. 5, 05.2013, p. 1192.
  • "Epigenomic plasticity enables human pancreatic α to β cell reprogramming." Journal of Clinical Investigation  In: , Vol. 123, No. 3, 01.03.2013, p. 1275-1284.
  • "Human pancreatic cancer fusion 2 (HPC2) 1-B3 : A novel monoclonal antibody to screen for pancreatic ductal dysplasia." Cancer cytopathology  In: , Vol. 121, No. 1, 01.2013, p. 37-46.
  • "Human thymic MR1-restricted MAIT cells are innate pathogen-reactive effectors that adapt following thymic egress." Mucosal Immunology  In: , Vol. 6, No. 1, 01.2013, p. 35-44.
  • "The novel monoclonal antibody HPC2 and N-cadherin distinguish pancreatic ductal adenocarcinoma from cholangiocarcinoma." Human Pathology  In: , Vol. 43, No. 10, 10.2012, p. 1583-1589.
  • "Pretargeting vs. direct targeting of human betalox5 islet cells subcutaneously implanted in mice using an anti-human islet cell antibody." Nuclear Medicine and Biology  In: , Vol. 39, No. 5, 07.2012, p. 645-651.
  • "Transcriptomes of the major human pancreatic cell types." Diabetologia  In: , Vol. 54, No. 11, 11.2011, p. 2832-2844.
  • "Human islet cell MORF/cMORF pretargeting in a xenogeneic murine transplant model." Molecular Pharmaceutics  In: , Vol. 8, No. 3, 06.06.2011, p. 767-773.
  • "Isolation of mouse pancreatic alpha, beta, duct and acinar populations with cell surface markers." Molecular and Cellular Endocrinology  In: , Vol. 339, No. 1-2, 06.06.2011, p. 144-150.
  • "The potential of human allogeneic juvenile chondrocytes for restoration of articular cartilage." American Journal of Sports Medicine  In: , Vol. 38, No. 7, 07.2010, p. 1324-1333.
  • "Immune evasion by neocartilage-derived chondrocytes : Implications for biologic repair of joint articular cartilage." Stem Cell Research  In: , Vol. 4, No. 1, 01.2010, p. 57-68.
  • "Generation of monoclonal antibodies specific for cell surface molecules expressed on early mouse endoderm." Stem Cells  In: , Vol. 27, No. 9, 09.2009, p. 2103-2113.
  • "Clinical scale expanded adult pluripotent stem cells prevent graft-versus-host disease." Cellular Immunology  In: , Vol. 255, No. 1-2, 2009, p. 55-60.
  • "Hematopoietic stem cells contribute to lymphatic endothelium." PLoS One  In: , Vol. 3, No. 11, e3812, 26.11.2008.
  • "Surface markers for the murine oval cell response." Hepatology  In: , Vol. 48, No. 4, 10.2008, p. 1282-1291.
  • "Isolation of major pancreatic cell types and long-term culture-initiating cells using novel human surface markers." Stem Cell Research  In: , Vol. 1, No. 3, 09.2008, p. 183-194.
  • "Pre-clinical safety testing supporting clinical use of allogeneic multipotent adult progenitor cells." Cytotherapy  In: , Vol. 10, No. 7, 2008, p. 730-742.
  • "Modification of the Woodruff-Stamper assay demonstrates binding of Toxoplasma gondii tachyzoites to retinal vascular endothelium." Journal of Immunological Methods  In: , Vol. 312, No. 1-2, 30.05.2006, p. 209-213.
  • "Donor marker infidelity in transgenic hematopoietic stem cells." Stem Cells  In: , Vol. 23, No. 5, 05.2005, p. 638-643.
  • "CD25 expression distinguishes functionally distinct alloreactive CD4+ CD134+ (OX40+) T-cell subsets in acute graft-versus-host disease." Biology of Blood and Marrow Transplantation  In: , Vol. 10, No. 5, 05.2004, p. 298-309.

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