Photo of Peter Mayinger, Ph.D.

Peter Mayinger Ph.D.

    • Associate Professor of Medicine, Division of Nephrology and Hypertension School of Medicine
    • Cell and Developmental Biology Graduate Program School of Medicine
    • Program in Molecular and Cellular Biosciences School of Medicine

Dr. Mayinger's research focuses on mermbranes and sorting, cell signaling, cell proliferation and differentiation, lipid signaling disorders, and cell proliferative diseases.


  • B.S., Technical University, Munich Germany 1986
  • Ph.D., Ludwig Maximilans University, Munich Germany 1992
  • Ph.D., Heidelberg University, Heidelberg Germany 2001
  • Fellowship:

    • Biological Chemistry - UCLA, 1992-1995

Memberships and associations

  • American Society of Nephrology


  • "Sac1p plays a crucial role in microsomal ATP transport, which is distinct from its function in Golgi phospholipid metabolism" EMBO Journal March 15 1999
  • "Delayed turnover of unphosphorylated Ssk1 during carbon stress activates the yeast Hog1 MAP kinase pathway" PLoS One September 4 2015
  • "Regulation of intracellular phosphatidylinositol-4-phosphate by the Sac1 lipid phosphatase" Traffic February 2005
  • "Phosphoregulatory protein 14-3-3 facilitates SAC1 transport from the endoplasmic reticulum" Proceedings of the National Academy of Sciences of the United States of America June 23 2015
  • "An ATP transporter is required for protein translocation into the yeast endoplasmic reticulum" EMBO Journal  1993
  • "Integration of Golgi trafficking and growth factor signaling by the lipid phosphatase SAC1" Journal of Cell Biology February 25 2008
  • "Spatial regulation of golgi phosphatidylinositol-4-phosphate is required for enzyme localization and glycosylation fidelity" Traffic September 2010
  • "A microsomal protein is involved in ATP-dependent transport of presecretory proteins into mammalian microsomes" EMBO Journal  1991
  • "Signaling at the Golgi" Cold Spring Harbor perspectives in biology May 2011
  • "The ADP/ATP carrier from yeast (AAC-2) is uniquely suited for the assignment of the binding center by photoaffinity labeling" FEBS Letters February 27 1989
  • "Sac1p mediates the adenosine triphosphate transport into yeast endoplasmic reticulum that is required for protein translocation" Journal of Cell Biology December 1995
  • "Photoaffinity labeling of dog pancreas microsomes with 8-azido-ATP inhibits association of nascent preprolactin with the signal sequence receptor complex" FEBS Letters July 29 1991
  • "The First Transmembrane Domain of Lipid Phosphatase SAC1 Promotes Golgi Localization" PLoS One August 1 2013
  • "Essential role for diacylglycerol in protein transport from the yeast Golgi complex" Nature May 1 1997
  • "Role for lipid signaling and the cell integrity MAP kinase cascade in yeast septum biogenesis" Current Genetics May 1 2003
  • "Growth control of golgi phosphoinositides by reciprocal localization of sac1 lipid phosphatase and pik1 4-kinase" Traffic November 2007
  • "Phosphoinositides and vesicular membrane traffic" Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids August 2012
  • "Analysis of phosphoinositide-binding proteins using liposomes as an affinity matrix" BioTechniques June 2005
  • "The Human Phosphatidylinositol Phosphatase SAC1 Interacts with the Coatomer I Complex" Journal of Biological Chemistry December 26 2003
  • "Regulation of Golgi function via phosphoinositide lipids" Seminars in Cell and Developmental Biology September 2009
  • "Effects of ATP on ligand recognition of platelet fibrinogen receptor on GPIIb-IIIa" American Journal of Physiology - Renal Fluid and Electrolyte Physiology  1994
  • "The phosphoinositide phosphatase Sac1p controls trafficking of the yeast Chs3p chitin synthase" Current Biology September 18 2001
  • "Reconstitution of yeast microsomal lipid flip-flop using endogenous aminophospholipids" FEBS Letters July 7 2000
  • "Inactivation of the phosphoinositide phosphatases Sac1p and Inp54p leads to accumulation of phosphatidylinositol 4,5-bisphosphate on vacuole membranes and vacuolar fusion defects" Journal of Biological Chemistry June 1 2007
  • "Cell growth-dependent coordination of lipid signaling and glycosylation is mediated by interactions between Sac1p and Dpm1p" Journal of Cell Biology January 17 2005
  • "Metabolic Activation of the HOG MAP Kinase Pathway by Snf1/AMPK Regulates Lipid Signaling at the Golgi" Traffic November 2012
  • "Labeling of two different regions of the nucleotide binding site of the uncoupling protein from brown adipose tissue mitochondria with two ATP analogs" Biochemistry  1992
  • "SAC1 lipid phosphatase and growth control of the secretory pathway" Molecular BioSystems  2009
  • "Expression of yeast lipid phosphatase Sac1p is regulated by phosphatidylinositol-4-phosphate" BMC Molecular Biology January 28 2008
  • "Retention of the yeast Sac1p phosphatase in the endoplasmic reticulum causes distinct changes in cellular phosphoinositide levels and stimulates microsomal ATP transport" Journal of Biological Chemistry March 22 2002

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