Photo of Peter Mayinger, Ph.D.

Peter Mayinger Ph.D.

    • Associate Professor of Medicine, Division of Nephrology and Hypertension School of Medicine
    • Cell and Developmental Biology Graduate Program School of Medicine
    • Program in Molecular and Cellular Biosciences School of Medicine

Dr. Mayinger's research focuses on mermbranes and sorting, cell signaling, cell proliferation and differentiation, lipid signaling disorders, and cell proliferative diseases.

Education

  • B.S., Technical University, Munich Germany 1986
  • Ph.D., Ludwig Maximilans University, Munich Germany 1992
  • Ph.D., Heidelberg University, Heidelberg Germany 2001
  • Fellowship:

    • Biological Chemistry - UCLA, 1992-1995

Memberships and associations

  • American Society of Nephrology

Publications

  • "Sac1p plays a crucial role in microsomal ATP transport, which is distinct from its function in Golgi phospholipid metabolism" EMBO Journal March 15 1999
  • "Delayed turnover of unphosphorylated Ssk1 during carbon stress activates the yeast Hog1 MAP kinase pathway" PLoS One September 4 2015
  • "Regulation of intracellular phosphatidylinositol-4-phosphate by the Sac1 lipid phosphatase" Traffic February 2005
  • "Phosphoregulatory protein 14-3-3 facilitates SAC1 transport from the endoplasmic reticulum" Proceedings of the National Academy of Sciences of the United States of America June 23 2015
  • "An ATP transporter is required for protein translocation into the yeast endoplasmic reticulum" EMBO Journal  1993
  • "Integration of Golgi trafficking and growth factor signaling by the lipid phosphatase SAC1" Journal of Cell Biology February 25 2008
  • "Spatial regulation of golgi phosphatidylinositol-4-phosphate is required for enzyme localization and glycosylation fidelity" Traffic September 2010
  • "A microsomal protein is involved in ATP-dependent transport of presecretory proteins into mammalian microsomes" EMBO Journal  1991
  • "Signaling at the Golgi" Cold Spring Harbor perspectives in biology May 2011
  • "The ADP/ATP carrier from yeast (AAC-2) is uniquely suited for the assignment of the binding center by photoaffinity labeling" FEBS Letters February 27 1989
  • "Sac1p mediates the adenosine triphosphate transport into yeast endoplasmic reticulum that is required for protein translocation" Journal of Cell Biology December 1995
  • "Photoaffinity labeling of dog pancreas microsomes with 8-azido-ATP inhibits association of nascent preprolactin with the signal sequence receptor complex" FEBS Letters July 29 1991
  • "The First Transmembrane Domain of Lipid Phosphatase SAC1 Promotes Golgi Localization" PLoS One August 1 2013
  • "Essential role for diacylglycerol in protein transport from the yeast Golgi complex" Nature May 1 1997
  • "Role for lipid signaling and the cell integrity MAP kinase cascade in yeast septum biogenesis" Current Genetics May 1 2003
  • "Growth control of golgi phosphoinositides by reciprocal localization of sac1 lipid phosphatase and pik1 4-kinase" Traffic November 2007
  • "Phosphoinositides and vesicular membrane traffic" Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids August 2012
  • "Analysis of phosphoinositide-binding proteins using liposomes as an affinity matrix" BioTechniques June 2005
  • "The Human Phosphatidylinositol Phosphatase SAC1 Interacts with the Coatomer I Complex" Journal of Biological Chemistry December 26 2003
  • "Regulation of Golgi function via phosphoinositide lipids" Seminars in Cell and Developmental Biology September 2009
  • "Effects of ATP on ligand recognition of platelet fibrinogen receptor on GPIIb-IIIa" American Journal of Physiology - Renal Fluid and Electrolyte Physiology  1994
  • "The phosphoinositide phosphatase Sac1p controls trafficking of the yeast Chs3p chitin synthase" Current Biology September 18 2001
  • "Reconstitution of yeast microsomal lipid flip-flop using endogenous aminophospholipids" FEBS Letters July 7 2000
  • "Inactivation of the phosphoinositide phosphatases Sac1p and Inp54p leads to accumulation of phosphatidylinositol 4,5-bisphosphate on vacuole membranes and vacuolar fusion defects" Journal of Biological Chemistry June 1 2007
  • "Cell growth-dependent coordination of lipid signaling and glycosylation is mediated by interactions between Sac1p and Dpm1p" Journal of Cell Biology January 17 2005
  • "Metabolic Activation of the HOG MAP Kinase Pathway by Snf1/AMPK Regulates Lipid Signaling at the Golgi" Traffic November 2012
  • "Labeling of two different regions of the nucleotide binding site of the uncoupling protein from brown adipose tissue mitochondria with two ATP analogs" Biochemistry  1992
  • "SAC1 lipid phosphatase and growth control of the secretory pathway" Molecular BioSystems  2009
  • "Expression of yeast lipid phosphatase Sac1p is regulated by phosphatidylinositol-4-phosphate" BMC Molecular Biology January 28 2008
  • "Retention of the yeast Sac1p phosphatase in the endoplasmic reticulum causes distinct changes in cellular phosphoinositide levels and stimulates microsomal ATP transport" Journal of Biological Chemistry March 22 2002

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