Oscar Miranda-Dominguez

  • Research Assistant Professor of Behavioral Neuroscience, School of Medicine

Biography

Oscar is a biomedical engineer with more than nine years of experience in research, industry and academy. He holds a Master’s Degree in Control Engineering and Automation (Tecnologico de Monterrey), and a PhD from the department of Biomedical Engineering at the University of Minnesota. He is currently a Research Assistant Professor in the Department of Behavioral Neuroscience in Oregon Health and Science University (OHSU) where he has developed expertise in neuroimaging and clinical research.

He has studied the brain at different spatiotemporal scales by using different mathematical frameworks and experimental approaches, going from single cell recordings in the hippocampal formation in rats to non-invasive functional MRI in mice, macaques and humans.

He has directed his training to developed methods and technologies combining the latest findings from neuroimaging, electrophysiology, and clinical psychology to identify biomarkers of psychiatric and neurological disorders at their earlier manifestations, and to build model-based approaches to therapeutics. To this end, he is using functional MRI to a) extract unique and stable personalized brain fingerprints in different species that can be detected with limited data, b) identify shared patterns of brain connectivity among groups that generalize across studies, and c) methods to bridge functional neuroimaging findings across species.

As a member of the Developmental Cognition and Neuroimaging (DCAN) laboratory he collaborates closely with the Parkinson’s Center of Oregon in several Projects aimed to characterize how brain function relates to cognition and mobility.

Education and training

    • B.S., 2000, Instituto Politecnico Nacional
    • M.S., 2001, Tecnologico de Monterrey
    • Ph.D., 2012, University of Minnesota
  • Fellowship

    • Global Biodesign Fellowship | Stanford University

Areas of interest

  • Neuroimaging
  • Neuromodulation
  • Mathematical modeling of physiological systems
  • Computational neuroscience
  • Data assimilation and signal processing
  • Design of medical devices
  • Closed loop control

Publications

Selected publications

  • "Heritability of the human connectome: A connectotyping study."Network Neuroscience, Volume 2, No. 2, Focus Feature: New Trends in Connectomics, p.175-199. Posted Online June 04, 2018
  • "Connectotyping: Model based fingerprinting of the functional connectome."PLoS One, vol. 9, no. 11, p. e111048, Nov. 2014.
  • "Bridging the gap between the human and macaque connectome: a quantitative comparison of global interspecies structure-function relationships and network topology." J. Neurosci., vol. 34, no. 16, pp. 5552–63, Apr. 2014.
  • "Firing rate control of a neuron using a linear proportional-integral controller." J Neural Eng, vol. 7, no. 6, p. 66004, Dec. 2010.

Publications

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