Photo of Nathan R. Selden, M.D., Ph.D., F.A.C.S., F.A.A.P.

Nathan R. Selden M.D., Ph.D., F.A.C.S., F.A.A.P.

    • Professor of Neurological Surgery School of Medicine
    • Mario and Edith Campagna Chair of Pediatric Neurological Surgery Neurological Surgery School of Medicine
    • Department Chair Neurological Surgery School of Medicine

Dr. Selden's scientific research focuses on basic mechanisms of pain sensation mediated by brainstem and limbic system pharmacological circuits. He was the co-principal investigator and surgeon for the first ever trial of human neural stem cell therapy, performing the first implant of neural stem cells in a patient in 2007. He also researches outcomes for neurosurgical care delivered to children with Chiari malformation and tethered spinal cord. In addition, Dr. Selden has a national and international reputation for studying new methods of neurosurgical education and continuing education that promote patient safety and quality. Finally, he is an author of the Pediatric Traumatic Brain Injury Guidelines, which are used around North America and in many countries around the world, The Rhetoric of Medicine: Lessons on Professionalism from Ancient Greece by Nigel Nicholson and Nathan Selden, and Pediatric Neurosurgery (Neurosurgery by Example) by Dr. Selden Nathan (Editor) and Dr. Baird Lissa (Editor).

Areas of interest

  • Pediatric epilepsy, Cranial Synostosis, Chiari Malformation, Tethered Spinal Cord, Neurosurgical Education


  • A.B., Stanford University, Stanford California 1986
  • Ph.D., Cambridge University, Cambridge 1990
  • M.D., Harvard Medical School, Boston Massachusetts 1993
  • Residency:

    • Neurosurgery, University of Michigan Medical Center, Ann Arbor, 1999
  • Fellowship:

    • Pediatric neurological surgery, Northwestern University Medical School, Chicago, 2000
  • Certifications:

    • American Board of Pediatric Neurological Surgery, 2011
    • American Board of Neurological Surgery, 2004

Honors and awards

  • British Marshall Scholar, 1986-89
  • Award of the American Academy of Neurological Surgery, 1998
  • ACGME Parker-Palmer Courage to Teach Award, 2013

Memberships and associations

  • Congress of Neurological Surgeons, Past-President
  • Society of Neurological Surgeons
  • American Association of Neurological Surgeons
  • American Academy of Neurological Surgery
  • American Society of Pediatric Neurosurgeons
  • Cambridge Philosophical Society
  • Fellow, American College of Surgeons
  • Fellow, American Academy of Pediatrics


Selected publications

  • The Rhetoric of Medicine: Lessons on Professionalism from Ancient Greece: Nigel Nicholson, Nathan Selden


  • "Self-assessment in neurological surgery" Neurosurgery October 2006
  • "Clipping versus coiling for ruptured intracranial aneurysms" Neurosurgery January 2010
  • "The competencies and safety." Neurosurgery  2007
  • "Ultrasonographic screening in infants with isolated spinal strawberry nevi" Journal of Neurosurgery April 1 2003
  • "Lumbar lipomyelomeningocele and sacrococcygeal teratoma in siblings" Journal of neurosurgery. Pediatrics June 2010
  • "Central nervous system stem cell transplantation for children with neuronal ceroid lipofuscinosis" Journal of neurosurgery. Pediatrics June 2013
  • "Benign radiographic coronal synostosis after sagittal synostosis repair" Journal of Craniofacial Surgery May 2013
  • "Nocifensive reflex-related on- and off-cells in the pedunculopontine tegmental nucleus, cuneiform nucleus, and lateral dorsal tegmental nucleus" Brain Research November 30 2005
  • "Test characteristics of quick brain MRI for shunt evaluation in children" Journal of neurosurgery. Pediatrics April 1 2015
  • "Results of a North American survey of rapid-sequence MRI utilization to evaluate cerebral ventricles in children" Journal of neurosurgery. Pediatrics  2014
  • "Commentary on 'Decompressive hemicraniectomy for pediatric traumatic brain injury" Pediatric Neurosurgery October 2011
  • "Modern treatment of cerebral metastases" Journal of Neuro-Oncology  2009
  • "Purinergic actions on neurons that modulate nociception in the rostral ventromedial medulla" Neuroscience June 8 2007
  • "Emergency neurosurgical care solutions" Neurosurgery April 2011
  • "Trajectories of cholinergic pathways within the cerebral hemispheres of the human brain" Brain  1998
  • "Minimal tethered cord syndrome associated with thickening of the terminal filum" Journal of Neurosurgery September 2006
  • "A single-pass tunneling technique for CSF shunting procedures" Pediatric Neurosurgery  2003
  • "The National Neurosurgery Quality and Outcomes Database (N2QOD)" Spine October 15 2014
  • "Emergency magnetic resonance imaging of cervical spinal cord injuries" Neurosurgery  1999
  • "Response" Journal of Neurosurgery August 2013
  • "Decreasing the effective radiation dose in pediatric craniofacial CT by changing head position" Pediatric Radiology December 2010
  • "Asymmetric ventriculomegaly, interhemispheric cyst, and dysgenesis of the corpus callosum (AVID)" Journal of Ultrasound in Medicine November 1 2012
  • "Chapter 1" Journal of Trauma and Acute Care Surgery June 1 2003
  • "Early Neurosurgical Procedures Enhance Survival in Blunt Head Injury" Journal of Emergency Medicine August 2009
  • "Using a 2-variable method in radionuclide shuntography to predict shunt patency" Journal of Neurosurgery December 1 2014
  • "Intracranial navigation using a novel device for endoscope fixation and targeting" Pediatric Neurosurgery September 2005
  • "Outcome science in practice" Neurosurgical Focus January 2013
  • "Human striatum" Neuroscience  1994
  • "Brainstem lesions in neurofibromatosis type 1" Neurosurgery October 2007
  • "Society of Neurological Surgeons boot camp courses" Journal of Neurosurgery September 2013

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