Biography
Michael Henderson is a biomedical engineering Ph.D. student in CEDAR after earning his bachelor's degree in biochemistry and molecular biology from Carroll College. Under the tutelage of Dr. Gaurav Sahay through consecutive OHSU internships and as a research assistant at Oregon State University, he studied gene delivery using lipid nanoparticles. His previous research experience spans chemical synthesis for clean energy storage, rational drug design, non-viral therapeutics for cystic fibrosis, cold storage of mRNA vaccines, mRNA delivery to the eye, and mRNA lipid nanoparticles as a platform for adjuvant therapies. Michael is co-mentored by Dr. Stuart Ibsen and Dr. Adem Yildirim. He aims to translate his diverse experience to uncover the mechanisms of sonodynamic effect and drug release from non-invasive stimuli. Raised in Portland, Oregon, the beauty of the Pacific Northwest shaped his passion for photography, mountaineering, and health outreach.
Education and training
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- B.S., 2021, Carroll College
Publications
Selected publications
- Leveraging Biological Buffers for Efficient Messenger RNA Delivery via Lipid Nanoparticles Molecular Pharmaceutics 2022 Michael I. Henderson, Yulia Eygeris, Antony Jozic, Marco Herrera, Gaurav Sahay
- Engineered mutant α-ENaC subunit mRNA delivered by lipid nanoparticles reduces amiloride currents in cystic fibrosis–based cell and mice models Sciences Advances 2020 Anindit Mukherjee, Kelvin D. Macdonald, Jeonghwan Kim, Michael I. Henderson, Yulia Eygeris, Gaurav Sahay
Publications
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