Meredith Kelleher, Ph.D.

  • Assistant Professor, Oregon National Primate Research Center

Biography

Meredith Kelleher is an Assistant Professor in the Division of Reproductive & Developmental Sciences at the Oregon National Primate Research Center (ONPRC). Dr. Kelleher graduated from the University of Newcastle, Australia with a Bachelor of Biomedical Sciences (Hons) and a PhD in Experimental Pharmacology, receiving an Australian Postgraduate Award for her Ph.D. studies on the effect of neurosteroid replacement therapy on perinatal brain development following premature birth. Dr. Kelleher has continued her studies of pregnancy and perinatal physiology, with a focus on intrauterine Ureaplasma infection, premature birth, hypoxic-ischemic encephalopathy and cerebral palsy. Dr. Kelleher was awarded a K99/R00 Pathway to Independence Award from NICHD in order to study the early stages of intrauterine infection that lead to preterm labor and perinatal neurodevelopmental injury. Dr. Kelleher also has ongoing collaborations examining potential therapies to prevent cerebral palsy and investigating perinatal brain injury associated with Zika virus infection during gestation.

Education and training

    • B.S., 2006, University of Newcastle
    • Ph.D., 2012, University of Newcastle
  • Certifications

    • Graduate Certificate in Human Investigations, OHSU, 2018
    • Biomedical Science Honours – 1st Class, University of Newcastle, Australia, 2007

Memberships and associations:

  • Society for Reproductive Investigation
  • American Society for Reproductive Immunology
  • American Association for the Advancement of Science
  • Fetal and Neonatal Physiological Society

Honors and awards

  • Travel Award, American Society for Reproductive Immunology Annual Meeting, Grand Rapids MI, 2019
  • Best Post-Doctoral Oral Presentation, Society for Neuroscience, Oregon Chapter Meeting, Edgefield OR, 2019
  • Miltenyi Biotech Award for Best Student Oral Presentation, Australian Society for Medical Research, NSW Scientific Meeting, 2011
  • 1st Place “10 of the Best” Research Showcase, Faculty of Health, University of Newcastle, NSW Australia, 2010
  • Australian Postgraduate Award (PhD Scholarship), Department of Industry, Innovation, Science, Research and Tertiary Education, Australian Federal Government, 2008-2012
  • Summer Research Scholarship, School of Biomedical Science, University of Newcastle, NSW Australia, 2005

Publications

Selected publications

  • Creatine Metabolism in Female Reproduction, Pregnancy and Newborn Health. Muccini AM, Tran NT, de Guingand DL, Philip M, Della Gatta PA, Galinsky R, Sherman LS, Kelleher MA, Palmer KR, Berry MJ, Walker DW, Snow RJ, Ellery SJ. Nutrients. 2021 Feb 2;13(2):490. doi: 10.3390/nu13020490. PMID: 33540766 Free PMC article. Review.
  • Maternal azithromycin therapy for Ureaplasma parvum intraamniotic infection improves fetal hemodynamics in a nonhuman primate model. Kelleher MA, Lee JY, Roberts VHJ, Novak CM, Baschat AA, Morgan TK, Novy MJ, Räsänen JP, Frias AE, Burd I. Am J Obstet Gynecol. 2020 Oct;223(4):578.e1-578.e11. doi: 10.1016/j.ajog.2020.04.015. Epub 2020 Apr 25. PMID: 32343954 Free PMC article.
  • A neonatal nonhuman primate model of gestational Zika virus infection with evidence of microencephaly, seizures and cardiomyopathy. Steinbach RJ, Haese NN, Smith JL, Colgin LMA, MacAllister RP, Greene JM, Parkins CJ, Kempton JB, Porsov E, Wang X, Renner LM, McGill TJ, Dozier BL, Kreklywich CN, Andoh TF, Grafe MR, Pecoraro HL, Hodge T, Friedman RM, Houser LA, Morgan TK, Stenzel P, Lindner JR, Schelonka RL, Sacha JB, Roberts VHJ, Neuringer M, et al. 
  • Beyond the uterine environment: a nonhuman primate model to investigate maternal-fetal and neonatal outcomes following chronic intrauterine infection. Kelleher MA, Liu Z, Wang X, Kroenke CD, Houser LA, Dozier BL, Martin LD, Waites KB, McEvoy C, Schelonka RL, Grigsby PL. Pediatr Res. 2017 Aug;82(2):244-252. doi: 10.1038/pr.2017.57. Epub 2017 May 24. PMID: 28422948 Free PMC article.
  • Changes in neuroactive steroid concentrations after preterm delivery in the Guinea pig. Kelleher MA, Hirst JJ, Palliser HK. Reprod Sci. 2013 Nov;20(11):1365-75. doi: 10.1177/1933719113485295. Epub 2013 Apr 12. PMID: 23585339 Free PMC article.