Photo of Martina Mancini, Ph.D.

Martina Mancini Ph.D.

Dr. Martina Mancini studies how to improve everyday functional mobility and prevent falls with rehabilitation interventions by investigating the pathophysiology of motor impairments and objectively characterizing them with new technologies. Using a variety of body worn sensors to characterize movement (i.e EMG, inertial sensors) and brain activity, this line of research will help in determine how the central nervous system integrates sensory information in healthy individuals and those with movement disorders, with a particular focus on Parkinson's disease. These novel, objective metrics of movement, combined with neurophysiological information, allows for the determination of optimal variable(s) to integrate with biofeedback, resulting in more effective rehabilitation interventions. This approach will bring new possibilities to monitor and condition functional mobility on a daily basis directly at home.

Education

  • B.S., University of Bologna Italy 2002
  • M.S., University of Bologna Italy 2005
  • Ph.D., University of Bologna Italy 2009

Publications

  • "Framework for understanding balance dysfunction in Parkinson's disease" Movement Disorders September 15 2013
  • "Objective biomarkers of balance and gait for Parkinson's disease using body-worn sensors" Movement Disorders September 15 2013
  • "Do clinical scales of balance reflect turning abnormalities in people With Parkinson's disease?" Journal of Neurologic Physical Therapy March 2012
  • "The relationship between balance control and vitamin D in Parkinson's disease-a pilot study" Movement Disorders July 2013
  • "Postural sway as a marker of progression in Parkinson's disease" Gait and Posture July 2012
  • "Turn detection and characterization with inertial sensors"   2013
  • "Levodopa Is a Double-Edged Sword for Balance and Gait in People With Parkinson's Disease" Movement Disorders September 1 2015
  • "Accelerometry reveals differences in gait variability between patients with multiple sclerosis and healthy controls" Annals of Biomedical Engineering August 2013
  • "Exploring outcome measures for exercise intervention in people with Parkinson's disease" Parkinson's Disease  2013
  • "Effects of Parkinson's disease and levodopa on functional limits of stability" Clinical Biomechanics May 2008
  • "Continuous monitoring of turning in patients with movement disability" Sensors December 27 2013
  • "Erratum" Annals of Biomedical Engineering September 2013
  • "Functional reorganization of the locomotor network in parkinson patients with freezing of gait" PLoS One June 17 2014
  • "Body-worn sensors capture variability, but not decline, of gait and balance measures in multiple sclerosis over 18 months" Gait and Posture  2014
  • "Trunk accelerometry reveals postural instability in untreated Parkinson's disease" Parkinsonism and Related Disorders August 2011
  • "Body-worn motion sensors detect balance and gait deficits in people with multiple sclerosis who have normal walking speed" Gait and Posture April 2012
  • "Do cognitive measures and brain circuitry predict outcomes of exercise in Parkinson Disease" BMC Neurology October 24 2015
  • "Instrumenting the balance error scoring system for use with patients reporting persistent balance problems after mild traumatic brain injury" Archives of Physical Medicine and Rehabilitation February 2014
  • "Inhibition, executive function, and freezing of gait" Journal of Parkinson's Disease  2014
  • "Continuous monitoring of turning in Parkinson's disease" NeuroRehabilitation August 22 2015
  • "ISway" Journal of NeuroEngineering and Rehabilitation  2012
  • "Step initiation in Parkinson's disease" Neuroscience Letters October 2 2006
  • "Quantifying freezing of gait in Parkinson's disease during the instrumented timed up and go test." Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference  2012
  • "The relevance of clinical balance assessment tools to differentiate balance deficits" European Journal of Physical and Rehabilitation Medicine June 2010
  • "Postural strategies assessed with inertial sensors in healthy and parkinsonian subjects" Gait and Posture  2014
  • "Dual-task interference and brain structural connectivity in people with Parkinson's disease who freeze" Journal of Neurology, Neurosurgery and Psychiatry July 1 2015
  • "Anticipatory postural adjustments prior to step initiation are hypometric in untreated Parkinson's disease" European Journal of Neurology September 2009
  • "Role of Body-Worn movement monitor technology for balance and Gait Rehabilitation" Physical Therapy March 1 2015
  • "Asymmetric pedunculopontine network connectivity in parkinsonian patients with freezing of gait" Brain  2013
  • "Effect of augmenting cholinergic function on gait and balance" BMC Neurology December 23 2015

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