Peer-Reviewed Publications

Langley BO, Ryan JJ, Phipps J, Buttolph L, Bray B, Aslan JE, Metz TO, Stevens JF, Bradley R. Xanthohumol microbiome and signature in adults with Crohn's disease (the XMaS trial): a protocol for a phase II triple-masked, placebo-controlled clinical trial. Trials. 2022 Oct 22;23(1):885.

Lamb JJ, Stone M, D’Adamo CR, Volkov A, Metti D, Aronica L, Minich D, Leary J, Class M, Carullo M, Ryan JJ, Larson IA, Lundquist E, Contractor N, Eck B, Ordovas JM, Bland JS. Personalized Lifestyle Intervention and Functional Evaluation Health Outcomes SurvEy: Presentation of the LIFEHOUSE Study Using N-of-One Tent–Umbrella–Bucket Design. Journal of Personalized Medicine. 2022, 12, 115. 

Langley BO, Guedry SE, Goldenberg JZ, Hanes DA, Beardsley JA, Ryan JJ. Inflammatory Bowel Disease and Neutrophil-Lymphocyte Ratio: A Systematic Scoping Review. Journal of Clinical Medicine. 2021; 10(18):4219. 

Ryan JJ, Monteagudo-Mera A, Contractor N, Gibson GR. Impact of 2’-Fucosyllactose on Gut Microbiota Composition in Adults with Inflammatory Gastrointestinal Conditions: Batch Culture Fermentation Model and Pilot Clinical Trial Findings. Nutrients. 2021, 13, 938. 

Langley BO, Ryan JJ, Hanes D, Phipps J, Stack E, Metz TO, Stevens JF, Bradley R. Xanthohumol Microbiome and Signature in Healthy Adults (the XMaS Trial): Safety and Tolerability Results of a Phase I Triple-Masked, Placebo-Controlled Clinical Trial. Molecular Nutrition & Food Research. 2021 Feb 25.  

Ryan JJ & Patno N. Short-Term Tolerability, Safety, and Gut Microbial Composition Responses to a Multi-Strain Probiotic Supplement: An Open Label Study in Healthy Adults. Integrative Medicine: A Clinician's Journal. 2021 Feb;20(1). 

Bradley R, Langley BO, Ryan JJ, Phipps J, Hanes DA, Stack E, Jansson JK, Metz TO, Stevens JF. Xanthohumol microbiome and signature in healthy adults (the XMaS trial): a phase I triple-masked, placebo-controlled clinical trial. Trials. 2020 Oct 7;21. 

Ryan JJ, Hanes DA, Bradley RD, Contractor N. Effect of a Nutrition Support Formula in Adults with Inflammatory Bowel Disease: A Pilot Study. Global Advances in Health and Medicine. 2019 Jul 29;8:1-8. 

Ryan JJ, Hanes DA, Corroon J, Taylor J, Bradley RD. Prospective Safety Evaluation of a Cardiovascular Health Dietary Supplement in Adults with Prehypertension and Stage I Hypertension. Journal of Alternative and Complementary Medicine. 2019 Feb;25(2):249-256. 

Ryan JJ, Hanes DA, Schafer MB, Mikolai J, Zwickey H. Effect of the probiotic Saccharomyces boulardii on cholesterol and lipoprotein particles in hypercholesterolemic adults: a single-arm, open-label pilot study. Journal of Alternative and Complementary Medicine. 2015 May;21(5):288-93.

Bisson WH, Zhang Z, Welsh K, Huang JW, Ryan J, Reed JC, Pellecchia M.  Binding properties of the C-terminal domain of VIAF. Chemical Biology & Drug Design. 2008 Nov;72(5):331-6. 

Lehtonen S, Shah M, Nielsen R, Iino N, Ryan JJ, Zhou H, Farquar MG.  The endocytic adaptor protein ARH associates with motor and centrosomal proteins and is involved in centrosome assembly and cytokinesis. Molecular Biology of the Cell. 2008 Jul;19(7):2949-61. 

Vazquez J, Tautz L, Ryan JJ, Vuori K, Mustelin T, Pellecchia M.  Development of molecular probes for second-site screening and design of protein tyrosine phosphatase inhibitors. Journal of Medicinal Chemistry. 2007 May 3;50(9):2137-43. 

Lehtonen S, Ryan JJ, Kudlicka K, Iino N, Zhou H, Farquar MG.  Cell junction-associated proteins IQGAP1, MAGI-2, CASK, spectrins, and α-actinin are components of the nephrin multiprotein complex.  Proceedings of the National Academy of Sciences. 2005 Jul 12;102(28):9814-9. 

Zhou W, Ryan JJ, Zhou H.   Global analyses of sumoylated proteins in Saccharomyces cerevisiae.   Induction of protein sumoylation by cellular stresses. Journal of Biological Chemistry. 2004 Jul 30;279(31):32262-8.