Headshot photo of Haylie Helms, M.S.

Haylie Helms, M.S.

  • Graduate Student, Biomedical Engineering Graduate Program, School of Medicine
  • Graduate Student, CEDAR, OHSU Knight Cancer Institute, School of Medicine
  • International Alliance for Cancer Early Detection (ACED), OHSU Knight Cancer Institute, School of Medicine


Haylie Helms received a bachelors in Biology from the University of Minnesota Twin Cities and a masters in Human Anatomy from the University of Colorado Anschutz Medical Campus. Before joining OHSU’s Biomedical Engineering PhD program, she managed the 3D Bioprinting Core Facility at the University of Minnesota, and also served as the Panoskaltsis-Mortari lab manager, taught a graduate level 3D Bioprinting course, and led several independent research projects.

Under the mentorship of Dr. Luiz Bertassoni, she is developing methods to single-cell bioprint complex tissues that match the native cellular spatial arrangement. Her research is currently focused on recreating the ductal carcinoma in situ (DCIS) tumor microenvironment, with single-cell spatial precision, to investigate cell-cell interactions driving disease progression to invasive breast cancer. By systematically manipulating the cellular composition and arrangement of the tumor microenvironment they hope to uncover the fundamental biology of tumor initiation and progression.

Education and training

    • B.A., 2017, University of Minnesota - Twin Cities
    • M.S., 2019, University of Colorado - Anshutz Medical Campus

Memberships and associations:

  • Biomedical Engineering Society (BMES), 2023 - Present
  • American Association for Cancer Research (AACR), 2023 - Present
  • International Alliance for Cancer Early Detection (ACED), 2022 - Present
  • International Society for Stem Cell Research (ISSCR), 2021 - 2023

Areas of interest

  • Tumor Microenvironment Spatial Biology
  • Tissue Engineering / Precision Biofabrication
  • Technology Development
  • Single-Cell Bioprinting

Honors and awards

  • • International Alliance for Cancer Early Detection (ACED) Scholar, 2022-2026
  • • Excellence in Research Nominee, OHSU All-Hill Student Council 2024
  • • Best Poster, Oregon Bioengineering Symposium 2023
  • • Best Poster Presentation, Oregon Bioengineering Symposium 2022
  • • Best Poster Presentation, OHSU BME Department Science Retreat 2022
  • • Best PhD Student Poster Presentation, OHSU School of Dentistry Research Day 2023
  • • Achievement Rewards for College Scientists (ARCS) Scholar, 2021-2024
  • • T90, NIDCR. Portland Oral Health Research Training Program, 2021-2022
  • • Douglas Strain Fellowship, 2021


Selected publications

  • Multiplex Single-Cell Bioprinting for Engineering of Heterogeneous Tissue Constructs with Subcellular Spatial Resolution. Helms HR, Oyama KA, Ware JP, Ibsen SD, Bertassoni LE. bioRxiv.  2024. DOI: 10.1101/2024.02.01.57849
  • Opportunities and Challenges to Engineer 3D Models of Tumor-Adaptive Immune Interactions. Visalakshan RM, Lowrey MK, Sousa MGC, Helms HR, Samiea A, Schutt CE, Moreau JM, Bertassoni LE. Frontiers in Immunology. 2023. DOI: 10.3389/fimmu.2023.1162905
  • Extracellular Matrix Microparticles Improve GelMA Bioink Resolution for 3D Bioprinting at Ambient Temperature. Galliger Z, Vogt CD, Helms HR, Panoskaltsis-Mortari A. Macromolecular Materials and Engineering. 2022. DOI: 10.1002/mame.202200196
  • Decellularization Strategies for Regenerating Cardiac and Skeletal Muscle Tissues. Tan YH*, Helms HR*, Nakayama KH. Frontiers in Bioengineering and Biotechnology. 2022; 10:831300. *Co-first author
  • An Experimental Study of the Recovery of Injured Porcine Lungs with Prolonged Normothermic Cellular Ex Vivo Lung Perfusion Following Donation after Circulatory Death. Spratt JR, Mattison LM, Iaizzo PA, Brown RZ, Helms H, Iles T, Howard BT, Panoskaltsis-Mortari A, Loor G. Transplant International. 2017; 30:932-944.
  • In Vitro Analysis of RBC-Mediated Lung Injury in Prolonged Ex Vivo Lung Perfusion. Spratt JR, Loor G, Mattison L, Meyer C, Ehrhardt M, Helms H, Panoskaltsis-Mortari A. The Journal of Heart and Lung Transplantation. 2017; 36 S311.
  • Prolonged EVLP using OCS Lung: Cellular and Acellular Perfusates. Loor G, Howard BT, Spratt JR, Mattison LM, Panoskaltsis-Mortari A, Iles TL, Meyer CM, Helms HR, Price A, Iaizzo PA. Transplantation. 2017; 101:2303-2311.


  • {{ pub.journalAssociation.journal.name.text[0].value }}