Gregory J. Baker, PhD, PharmD (he/him)

  • Assistant Professor, Division of Oncological Sciences, School of Medicine
  • Joint Faculty, Biomedical Engineering, School of Medicine
  • Member, Knight Cancer Institute (KCI)
  • Member, Center for Biomedical Data Science (CBDS)
  • Member, Cancer Early Detection Advanced Research Center (CEDAR)
  • Member, School of Medicine Graduate Faculty
  • Member, KCI Quantitative Oncology Program

Biography

Gregory Baker, PhD, PharmD, is an Assistant Professor in the Division of Oncological Sciences at the OHSU Knight Cancer Institute, with a joint appointment in the Department of Biomedical Engineering and membership in the Knight Cancer Institute. His research integrates approaches to immune response profiling and AI-driven biomedical tissue imaging to improve early cancer detection and interception for glioblastoma (GBM) brain cancer.

Professor Baker completed his postdoctoral training at Harvard Medical School in the Laboratory of Systems Pharmacology together with Peter Sorger, Ph.D. There, he developed tools to study cancer immune responses at single-cell resolution. His work includes SYLARAS (Baker et al. Cell Systems, 2020), a platform for profiling systemic immune responses in preclinical systems, and a suite of open-source tools for analyzing multiplexed immunofluorescence images of tissue, including MCMICRO for image assembly (Schapiro et al. Nature Methods 2022), CyLinter for quality control (Baker et al. Nature Methods 2024), and MORPHÆUS for AI-driven image analysis (bioRxiv).

Professor Baker earned his Ph.D. in Molecular & Medical Pharmacology from the University of California, Los Angeles (UCLA), where he studied brain tumor immunology with Drs. Pedro Lowenstein M.D., Ph.D. and Maria Castro Ph.D., and was a postdoctoral fellow in the Department of Neurosurgery at the University of Michigan. He also holds a Doctorate in Pharmacy (Pharm.D.) from the University of Rhode Island, graduating summa cum laude.

Over the past 17 years, Professor Baker’s work has focused on GBM, an aggressive and lethal brain tumor. His research has led to numerous publications on key aspects of GBM biology, including its neo-angiogenesis, invasion and immune dynamics. Links to his publications are provided below.

In his free time, he enjoys spending time with family, playing electric guitar and listening to music.

Education and training

  • Degrees

    • Ph.D., 2014, University of California, Los Angeles
    • Pharm.D., 2007, University of Rhode Island
  • Fellowship

    • American Cancer Society Postdoctoral Fellow (2017-2020)

Memberships and associations:

  • American Association for Cancer Research (AACR)
  • Analysis Working Group, NCI Cancer Systems Biology Consortium

Areas of interest

  • Cancer systems immunology
  • Cancer early detection
  • Computational Pathology
  • Glioblastoma
  • Immunotherapy

Honors and awards

  • Member, Scientific Advisory Board, Cellformatica (2025-Present)
  • Grand Prize, NCI Cancer Systems Biology Consortium Image Analysis Hackathon (2022)
  • “Outstanding Achievement in Biomedical Research Award", URI College of Pharmacy (2007)

Publications

Elsevier pure profile

Publications