Photo of Deborah A. Lewinsohn, M.D.

Deborah A. Lewinsohn M.D.

    • Professor of Pediatrics, Division of Infectious Diseases School of Medicine
    • Wayne L. Tracy Professor of Pediatric Infectious Disease Pediatrics School of Medicine
    • Molecular Microbiology and Immunology Graduate Program School of Medicine
    • Program in Molecular and Cellular Biosciences School of Medicine

Lab:http://www.ohsu.edu/xd/health/services/doernbecher/research-education/research/research-labs/deborah-lewinsohn-lab.cfm

  • Residency:

    • University of California-San Francisco
  • Fellowship:

    • University of Washington, Seattle

Publications

  • "Embracing IGRAs in children" International Journal of Tuberculosis and Lung Disease June 2010
  • "CD8 + T cells provide an immunologic signature of tuberculosis in young children" American Journal of Respiratory and Critical Care Medicine January 15 2012
  • "The Mycobacterium tuberculosis Phagosome Is a HLA-I Processing Competent Organelle" PLoS Pathogens April 2009
  • "Transfer of specificity for human immunodeficiency virus type 1 into primary human T lymphocytes by introduction of T-cell receptor genes" Journal of Virology  2000
  • "HLA-E-dependent presentation of Mtb-derived antigen to human CD8+ T cells" Journal of Experimental Medicine December 2 2002
  • "Rudimentary TCR signaling triggers default IL-10 secretion by human TH1 cells" Journal of Immunology October 15 2001
  • "HIV-specific cytotoxic T lymphocytes traffic to lymph nodes and localize at sites of HIV-1 replication and cell death (Journal of Clinical Investigation (2000) 105, (1407-1417) DOI" Journal of Clinical Investigation May 1 2008
  • "Embracing interferon-γ release assays for diagnosis of latent tuberculosis infection" Pediatric Infectious Disease Journal August 2009
  • "The antiviral activity of HIV-specific CD8+ CTL clones is limited by elimination due to encounter with HIV-infected targets" Journal of Immunology July 15 1999
  • "Whole blood interferon-gamma responses to Mycobacterium tuberculosis antigens in young household contacts of persons with tuberculosis in Uganda" PLoS One October 15 2008
  • "Loss of naive T cells and repertoire constriction predict poor response to vaccination in old primates" Journal of Immunology June 15 2010
  • "New diagnostic methods for tuberculosis" Current Opinion in Infectious Diseases April 2009
  • "Mycobacterium tuberculosis-specific CD8+ T Cells Preferentially Recognize Heavily Infected Cells" American Journal of Respiratory and Critical Care Medicine December 1 2003
  • "Interferon-γ release assays for diagnosing mycobacterium tuberculosis infection in renal dialysis patients" Clinical Journal of the American Society of Nephrology September 2008
  • "TB Vaccines at the Turn of the Century" Seminars in Respiratory Infections December 2003
  • "Human Neonatal Dendritic Cells Are Competent in MHC Class I Antigen Processing and Presentation" PLoS One  2007
  • "HIV-specific cytotoxic T lymphocytes traffic to lymph nodes and localize at sites of HIV replication and cell death (Journal of Clinical Investigation (2010) 120, 9, (3401) doi" Journal of Clinical Investigation September 1 2010
  • "Human thymic MR1-restricted MAIT cells are innate pathogen-reactive effectors that adapt following thymic egress" Mucosal Immunology January 2013
  • "Application of T cell immunotherapy for human viral and malignant diseases." Ernst Schering Research Foundation workshop  2000
  • "Childhood tuberculosis in Northern Viet Nam" PLoS One May 12 2014
  • "Interferon-γ release assays" Current Opinion in Pediatrics February 2010
  • "Human mucosal associated invariant T cells detect bacterially infected cells" PLoS Biology June 2010
  • "In vivo migration and function of transferred HIV-1-specific cytotoxic T cells" Nature Medicine  1999
  • "Human Mycobacterium tuberculosis CD8 T Cell Antigens/Epitopes Identified by a Proteomic Peptide Library" PLoS One June 21 2013
  • "Immunotherapy of human viral and malignant diseases with genetically modified T-cell clones" Cancer Journal (United States) May 2000
  • "Tuberculosis immunology in children" International Journal of Tuberculosis and Lung Disease May 2004
  • "High resolution radiographic and fine immunologic definition of TB disease progression in the rhesus macaque" Microbes and Infection September 2006
  • "HIV-specific cytotoxic T lymphocytes traffic to lymph nodes and localize at sites of HIV replication and cell death" Journal of Clinical Investigation May 2000
  • "Mycobacterium tuberculosis specific CD8+ T cells rapidly decline with antituberculosis treatment" PLoS One December 4 2013
  • "Secreted immunodominant Mycobacterium tuberculosis antigens are processed by the cytosolic pathway" Journal of Immunology October 1 2010

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