Photo of Carol J. MacArthur, M.D.

Carol J. MacArthur M.D.

  • (503) 494-5350
    • Professor of Otolaryngology - Head and Neck Surgery School of Medicine
    • Professor of Otolaryngology - Head and Neck Surgery, Division of Pediatric Otolaryngology School of Medicine

Dr. MacArthur joined the Department of Otolaryngology-Head and Neck Surgery at OHSU in 2002. She came from Children's Hospital of Orange County (CHOC) and the University of California, Irvine in Orange, California where she was in practice from 1991-2002. Dr. MacArthur completed a pediatric otolaryngology fellowship at Harvard Medical School/Boston Children's Hospital, in Boston, Massachusetts before beginning her practice in 1991. She completed her training in otolaryngology-head and neck surgery at the University of California, Davis. She received her medical degree at UCLA and undergraduate degree in chemistry at Occidental College in Los Angeles, CA.

Dr. MacArthur has a strong clinical interest in the treatment of hemangiomas and vascular birthmarks. She co-founded the hemangioma and vascular birthmarks team at OHSU in 2003. This team provides multidisciplinary care to children and adults with complex hemangiomas and vascular birthmarks, offering the most up-to-date treatment options, both medical and surgical and via interventional radiology. 

She is an active mentor to students and residents. She is chief of the Division of Pediatric Otolaryngology here at OHSU and is starting a fellowship program to train future leaders in this field. She has over 40 peer-reviewed publications, is active in editorial review activities for several medical journals and granting agencies. She serves on numerous committees to support the OHSU institution in Professionalism, faculty council and as co-chair of the Committee on Committees. She also serves on the American Society of Pediatric Otolaryngology Task Forces on fellowship, vascular birthmarks, research, voice, and recurrent respiratory papillomas. 

In addition, from 2005-2014, Dr. MacArthur was funded through the NIH as a co-investigator with Dennis Trune, Ph.D. to study the inner ear impact of chronic middle ear inflammation (mouse model), steroid responsive mechanisms in the ear (mouse model), and the genetic susceptibility to otitis media –candidate genes. She also received a grant from the National Organization for Hearing Research (NOHR) in 2011 to study the genetic variation in the immune system to otitis media. She collaborates with an international group interested in the genetics of chronic otitis media including research teams from the UK, Finland, Pittsburgh and Australia on this effort. She has recently received a grant from the  "Action on Hearing Loss" Foundation in 2015 to continue the genetic investigation of chronic otitis media.

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Education

  • B.A., Occidental College, Los Angeles California 1979
  • M.D., University of California Los Angeles, Los Angeles California 1984
  • Internship:

    • Intern, General Surgery, 1984-1985
  • Fellowship:

    • Pediatric Otolaryngology, Boston Children's Hospital, Harvard Medical School, 1990-1991
  • Certifications:

    • American Board of Otolaryngology, 1990

Memberships and associations

  • American Academy of Otolaryngology/Head and Neck Surgery

Publications

  • "Paranasal phycomycosis in the immunocompetent host" Otolaryngology - Head and Neck Surgery (United States)  1992
  • "Mouse models of otitis media" Current Opinion in Otolaryngology and Head and Neck Surgery October 2006
  • "Otitis media" Laryngoscope December 2012
  • "Inner ear tissue remodeling and ion homeostasis gene alteration in murine chronic otitis media" Otology and Neurotology February 2013
  • "Control of chronic otitis media and sensorineural hearing loss in C3H/HeJ mice" Otolaryngology - Head and Neck Surgery (United States) November 2008
  • "Steroid control of acute middle ear inflammation in a mouse model" JAMA Otolaryngology - Head and Neck Surgery May 2009
  • "Correlative mRNA and protein expression of middle and inner ear inflammatory cytokines during mouse acute otitis media" Hearing Research August 1 2015
  • "Head and neck hemangiomas of infancy" Current Opinion in Otolaryngology and Head and Neck Surgery December 2006
  • "Pediatric plastic bronchitis" International Journal of Pediatric Otorhinolaryngology Extra March 2010
  • "Variations of the anterior cricoid split" Laryngoscope  1992
  • "Multicenter interrater and intrarater reliability in the endoscopic evaluation of velopharyngeal insufficiency" JAMA Otolaryngology - Head and Neck Surgery July 2008
  • "Innate immunity gene single nucleotide polymorphisms and otitis media" International Journal of Pediatric Otorhinolaryngology July 2012
  • "Vincristine-induced recurrent laryngeal nerve paralysis" Laryngoscope  1992
  • "C3H/HeJ mouse model for spontaneous chronic otitis media" Laryngoscope July 2006
  • "Simultaneous measurement of multiple ear proteins with multiplex ELISA assays" Hearing Research May 2011
  • "Pediatric aerodigestive foreign body injuries are complications related to timeliness of diagnosis" Laryngoscope January 1997
  • "Intratympanic Steroid Treatments May Improve Hearing via Ion Homeostasis Alterations and Not Immune Suppression" Otology and Neurotology July 26 2015
  • "Evaluation of the mouse model for acute otitis media" Hearing Research September 2006
  • "Gram-negative pathogen Klebsiella oxytoca is associated with spontaneous chronic otitis media in Toll-like receptor 4-deficient C3H/HeJ mice" Acta Oto-Laryngologica  2008
  • "Altered expression of middle and inner ear cytokines in mouse otitis media" Laryngoscope February 2011
  • "Predisposition to childhood otitis media and genetic polymorphisms within the toll-like receptor 4 (TLR4) Locus" PLoS One July 15 2015
  • "The effect of the palatoplasty method on the frequency of ear tube placement" JAMA Otolaryngology - Head and Neck Surgery October 2008
  • "Pediatric head and neck rhabdomyosarcoma" Clinical Pediatrics  1992
  • "Efficacy of tonsillectomy for pediatric patients with dysphagia and tonsillar hypertrophy" JAMA Otolaryngology - Head and Neck Surgery December 2011
  • "Otolaryngologic manifestations of Multiple Pterygium Syndrome" International Journal of Pediatric Otorhinolaryngology January 1996
  • "Prenatal diagnosis of fetal cervicofacial anomalies" Current Opinion in Otolaryngology and Head and Neck Surgery December 2012
  • "Outcomes of tympanostomy tube placement in children with Down syndrome-A retrospective review" International Journal of Pediatric Otorhinolaryngology February 2014
  • "Murine middle ear inflammation and ion homeostasis gene expression" Otology and Neurotology April 2011
  • "Primary atrophic rhinitis" Otolaryngology - Head and Neck Surgery (United States)  1997
  • "Propranolol-responsive cranial nerve palsies in a patient with PHACES syndrome" International Journal of Pediatric Otorhinolaryngology October 1 2015

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