Photo of Bruce Jeffrey Schnapp, Ph.D.

Bruce Jeffrey Schnapp Ph.D.

  • (503) 494-8994
    • Professor of Cell, Developmental and Cancer Biology School of Medicine
    • Cell and Developmental Biology Graduate Program School of Medicine
    • Program in Molecular and Cellular Biosciences School of Medicine

Bruce Schnapp is a Professor in the Department of Cell, Developmental and Cancer Biology. He earned his B.S. (Biology) in 1972 and his Ph.D. (Neuroscience) in 1976 at the University of Connecticut. After postdoctoral work in the Department of Neurobiology at Harvard Medical School, Dr. Schnapp joined the intramural program at NIH in 1983, and maintained his lab off campus at the Marine Biological Laboratory in Woods Hole, MA until 1989. Dr. Schnapp was Associate Professor in the Department of Physiology at Boston University Medical School (1989-1990) before moving his lab to Department of Cell Biology at Harvard Medical School (1991-2001), and then to OHSU in 2001.

Areas of interest

  • cell biology; transport; kinesin; dynein; myosin; zebrafish; melanocytes

Publications

  • "Zebrafish Melanophilin Facilitates Melanosome Dispersion by Regulating Dynein." Current Biology  In: , Vol. 17, No. 20, 23.10.2007, p. 1721-1734.
  • "A change in the selective translocation of the kinesin-1 motor domain marks the initial specification of the axon." Neuron  In: , Vol. 49, No. 6, 16.03.2006, p. 797-804.
  • "A repeated IMP-binding motif controls oskar mRNA translation and anchoring independently of Drosophila melanogaster IMP." Journal of Cell Biology  In: , Vol. 172, No. 4, 13.02.2006, p. 577-588.
  • "Trafficking of signaling modules by kinesin motors." Journal of Cell Science  In: , Vol. 116, No. 11, 01.06.2003, p. 2125-2135.
  • "UUCAC- and Vera-dependent localization of VegT RNA in Xenopus oocytes." Current Biology  In: , Vol. 12, No. 7, 02.04.2002, p. 558-564.
  • "RNA localization : SHEdding light on the RNA-motor linkage." Current Biology  In: , Vol. 11, No. 5, 06.03.2001.
  • "Cargo of kinesin identified as JIP scaffolding proteins and associated signaling molecules." Journal of Cell Biology  In: , Vol. 152, No. 5, 05.03.2001, p. 959-970.
  • "Dynactin-dependent, dynein-driven vesicle transport in the absence of membrane proteins : A role for spectrin and acidic phospholipids." Molecular Cell  In: , Vol. 7, No. 1, 2001, p. 173-183.
  • "RNA localization : A glimpse of the machinery." Current Biology  In: , Vol. 9, No. 19, 07.10.1999.
  • "The kinesin motor KIF3A is a component of the presynaptic ribbon in vertebrate photoreceptors." Journal of Neuroscience  In: , Vol. 19, No. 3, 01.02.1999, p. 1027-1037.
  • "Light chain-dependent regulation of kinesin's interaction with microtubules." Journal of Cell Biology  In: , Vol. 143, No. 4, 16.11.1998, p. 1053-1066.
  • "A highly conserved RNA-binding protein for cytoplasmic mRNA localization in vertebrates." Current Biology  In: , Vol. 8, No. 9, 23.04.1998, p. 489-496.
  • "KIF3C and KIF3A form a novel neuronal heteromeric kinesin that associates with membrane vesicles." Molecular Biology of the Cell  In: , Vol. 9, No. 3, 1998, p. 637-652.
  • "RNA localization in Xenopus oocytes." Seminars in Cell and Developmental Biology  In: , Vol. 8, No. 6, 12.1997, p. 529-540.
  • "Projecting two-axis nanometer scale displacement of microscopic beads onto a quadrant photodetector with a laser beam." Review of Scientific Instruments  In: , Vol. 68, No. 10, 10.1997, p. 3920-3921.
  • "Localization of Xenopus Vg1 mRNA by Vera protein and the endoplasmic reticulum." Science  In: , Vol. 276, No. 5315, 16.05.1997, p. 1128-1131.
  • "Improved nm displacement detector for microscopic beads at frequencies below 10 Hz." Review of Scientific Instruments  In: , Vol. 68, No. 5, 05.1997, p. 2195-2199.
  • "Retroactive motors." Neuron  In: , Vol. 18, No. 4, 1997, p. 523-526.
  • "Erratum : Improved nm displacement detector for microscopic beads at frequencies below 10 Hz (Rev. Sci. Instrum. (1997) 68(5) (2195–2199) (10.1063/1.1148070))." Review of Scientific Instruments  In: , Vol. 68, No. 7, 1997, p. 2915.
  • "Plus-end motors override minus-end motors during transport of squid axon vesicles on microtubules." Journal of Cell Biology  In: , Vol. 135, No. 2, 10.1996, p. 383-397.
  • "Optimized filter set and viewing conditions for the S65T mutant of GFP in living cells." BioTechniques  In: , Vol. 21, No. 2, 08.1996, p. 220-226.
  • "Kinetics of spindle pole body separation in budding yeast." Proceedings of the National Academy of Sciences of the United States of America  In: , Vol. 92, No. 21, 10.10.1995, p. 9707-9711.
  • "Two heads are better than one." Nature  In: , Vol. 373, No. 6516, 1995, p. 655-656.
  • "Direct observation of kinesin stepping by optical trapping interferometry." Nature  In: , Vol. 365, No. 6448, 21.10.1993, p. 721-727.
  • "Single kinesin molecules crossbridge microtubules in vitro." Proceedings of the National Academy of Sciences of the United States of America  In: , Vol. 90, No. 14, 15.07.1993, p. 6503-6507.
  • "Kinesin is bound with high affinity to squid axon organelles that move to the plus-end of microtubules." Journal of Cell Biology  In: , Vol. 119, No. 2, 10.1992, p. 389-399.
  • "Bead movement by single kinesin molecules studied with optical tweezers." Nature  In: , Vol. 348, No. 6299, 22.11.1990, p. 348-352.
  • "The primary structure and analysis of the squid kinesin heavy chain." Journal of Biological Chemistry  In: , Vol. 265, No. 6, 25.02.1990, p. 3278-3283.
  • "Delayed start-up of kinesin-driven microtubule gliding following inhibition by adenosine 5′-[β,γ-imido]triphosphate." Proceedings of the National Academy of Sciences of the United States of America  In: , Vol. 87, No. 24, 1990, p. 10053-10057.
  • "Nanometer measurements of motor protein and membrane glycoprotein movements." Proceedings of SPIE - The International Society for Optical Engineering  In: , Vol. 1161, 22.12.1989, p. 264-265.

Additional information

Edit profile