Our overarching goal is to identify novel drivers of disease initiation, progression, and drug resistance in leukemia and to ultimately translate these discoveries into treatments for leukemia patients. Specifically, our lab is interested in understanding the composite interplay of genetic events and the tumor microenvironment that are requisite for promoting the growth of leukemia cells and conferring drug resistance. To achieve these goals, we have developed various functional assays which we employ in tandem with genomic and proteomic approaches. We take a multidisciplinary approach and utilize various state-of-art techniques to dissect the functional role and therapeutic relevance of identified pathways. Our goal is to use this knowledge to improve the understanding of disease pathobiology and inform the development of novel, molecularly targeted therapies for patients.
- B.S., C. C. S. University, Meerut India 1996
- M.S., G.B. Pant University, Pantnagar India 1998
- Ph.D., Dr. R.M.L. Avadh University, Faizabad India 2003
Memberships and associations
- American Society of Hematology