Photo of Alison Skalet, M.D., Ph.D.

Alison Skalet M.D., Ph.D.

  • (503) 494-7881
    • Associate Professor of Ophthalmology School of Medicine
    • Casey Eye Institute School of Medicine
    • Ophthalmology School of Medicine

Dr. Skalet specializes in treating adult and pediatric patients with ocular tumors. She enjoys working with an outstanding team of professionals dedicated to the care of patients with cancers of the eye. She provides medical and surgical care for patients with a wide variety of benign and malignant eye tumors, including retinoblastoma, uveal and conjunctival melanoma, metastatic lesions, intraocular lymphoma, and vascular tumors. Her goal is to provide care that is both cutting-edge and compassionate.

Dr. Skalet combines her busy clinical practice with clinical and translational research. Her current research interests include the evaluation of circulating tumor cells as a biomarker in uveal melanoma, collaborative clinical research investigating trends in clinical care and outcomes, investigation of novel ophthalmic imaging modalities including optical coherence tomography angiography, and clinical trials in ocular oncology.

Dr. Skalet has enjoyed serving on multiple national and international subspecialty committees for the American Academy of Ophthalmology, American Board of Ophthalmology, American Association of Ophthalmic Oncologists and Pathologists, and the International Society of Ocular Oncology.

In her free time, Dr. Skalet loves to spend time with her family exploring all the Pacific Northwest has to offer. She enjoys hiking, skiing, reading and singing.

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  • B.S., Tulane University, New Orleans Louisiana 1998
  • Ph.D., University of Pennsylvania, Philadelphia Pennsylvania 2005
  • M.D., University of Pennsylvania, Philadelphia Pennsylvania 2006
  • Internship:

    • Internship, pediatrics, The Children’s Hospital of Philadelphia, 2007
  • Residency:

    • Ophthalmology, University of California, San Francisco
  • Fellowship:

    • Ocular oncology and ophthalmic pathology, Casey Eye Institute/Oregon Health & Science University, Portland, 2012
  • Certifications:

    • American Board of Ophthalmology, 2012

Memberships and associations

  • American Academy of Ophthalmology
  • American Association of Ophthalmic Oncologists and Pathologists
  • International Society of Ocular Oncology


  • "Rapid B cell receptor-induced unfolded protein response in nonsecretory B cells correlates with pro- versus antiapoptotic cell fate" Journal of Biological Chemistry December 2 2005
  • "Accuracy and reliability of telemedicine for diagnosis of cytomegalovirus retinitis" American Journal of Ophthalmology December 2011
  • "Clinical features of newly diagnosed cytomegalovirus retinitis in Northern Thailand" American Journal of Ophthalmology May 2012
  • "Anterior uveitis associated with high-dose cytosine arabinoside" Ocular Immunology and Inflammation December 2010
  • "Telemedicine screening for retinopathy of prematurity in developing countries using digital retinal images" Journal of AAPOS June 2008
  • "Antibiotic selection pressure and macrolide resistance in Nasopharyngeal Streptococcus pneumoniae" PLoS Medicine December 2010
  • "Human cytomegalovirus infection activates and regulates the unfolded protein response" Journal of Virology June 2005
  • "Vitreous veils associated with congenital X-linked retinoschisis" JAMA Ophthalmology August 1 2015
  • "Inflammatory myofibroblastic tumor of the orbit" Ophthalmic Plastic and Reconstructive Surgery  2015
  • "More to mutton than meets the eye" Journal of General Internal Medicine September 2010
  • "Optical Coherence Tomography Angiography Characteristics of Iris Melanocytic Tumors" Ophthalmology February 1 2017
  • "Retinoblastoma and Neuroblastoma predisposition and surveillance" Clinical Cancer Research July 1 2017
  • "Screening Children at Risk for Retinoblastoma. Consensus Report from the American Association of Ophthalmic Oncologists and Pathologists" Ophthalmology  2017
  • "Association between Tumor Regression Rate and Gene Expression Profile after Iodine 125 Plaque Radiotherapy for Uveal Melanoma" Ophthalmology October 1 2017
  • "Optical coherence tomography angiography of a pigmented Fuchs' adenoma (age-related hyperplasia of the nonpigmented ciliary body epithelium) masquerading as a ciliary body melanoma" American Journal of Ophthalmology Case Reports March 1 2018
  • "Vision loss from choroidal and pituitary metastases secondary to renal cell carcinoma" Neuro-Ophthalmology June 18 2018
  • "Uveal Melanoma with Histopathologic Intratumoral Heterogeneity Associated with Gene Expression Profile Discordance" Ocular Oncology and Pathology July 1 2017
  • "Reply" Ophthalmology September 1 2018
  • "Metastases and death rates after primary enucleation of unilateral retinoblastoma in the USA 2007-2017" British Journal of Ophthalmology January 1 2018
  • "Trends in Radiation Practices for Female Ocular Oncologists in North America" Ocular Oncology and Pathology January 1 2019
  • "Corneal Substructure Dosimetry Predicts Corneal Toxicity in Patients With Uveal Melanoma Treated With Proton Beam Therapy" International Journal of Radiation Oncology Biology Physics January 1 2019
  • "Quantitative OCT Angiography Evaluation of Peripapillary Retinal Circulation after Plaque Brachytherapy" Ophthalmology Retina March 1 2018

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