Photo of Stephen Planck, Ph.D.

Stephen Planck Ph.D.

    • Professor of Ophthalmology School of Medicine
    • Cell and Developmental Biology Graduate Program School of Medicine
    • Program in Molecular and Cellular Biosciences School of Medicine
    • Casey Eye Institute School of Medicine

Joint appointments Research Associate Professor, Cell & Developmental Biology; Research Associate Professor, Medicine - Division of Arthritis and Rheumatic Diseases

Education

B.S., University of California, 1970, Biochemistry Ph.D., University of Wisconsin, 1976, Oncology

Professional Experience

Postdoctoral Fellow, National Cancer Institute, NIH, Bethesda, MD, 1976-1979 Research Assistant Professor, University of Arizona, 1979-1984 Research Assistant/Associate Professor, Oregon Health & Science University, 1984-present

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Education

  • B.S., University of California, 0 1970
  • Ph.D., University of Wisconsin, 0 1976
  • Fellowship:

    • Postdoctoral Fellow, National Cancer Institute, NIH, Bethesda, MD, 1976-1979

Publications

  • "Gene expression profiling and heterogeneity of nonspecific orbital inflammation affecting the lacrimal gland." JAMA Ophthalmology In: , Vol. 135, No. 11, 01.11.2017, p. 1156-1162.
  • "Molecular diagnosis : Implications for ophthalmology." Progress in Retinal and Eye Research In: , Vol. 50, 01.01.2016, p. 25-33.
  • "Orbital pseudotumor can be a localized form of granulomatosis with polyangiitis as revealed by gene expression profiling." Experimental and Molecular Pathology In: , Vol. 99, No. 2, 01.10.2015, p. 271-278.
  • "Fibrosis, gene expression and orbital inflammatory disease." British Journal of Ophthalmology In: , Vol. 99, No. 10, 01.10.2015, p. 1424-1429.
  • "The role of the immune response in the pathogenesis of thyroid eye disease : A reassessment." PLoS One In: , Vol. 10, No. 9, e0137654, 15.09.2015.
  • "Parallel gene expression changes in sarcoidosis involving the lacrimal gland, orbital tissue, or blood." JAMA Ophthalmology In: , Vol. 133, No. 7, 01.07.2015, p. 770-777.
  • "Molecular diagnosis of orbital inflammatory disease." Experimental and Molecular Pathology  In: , Vol. 98, No. 2, 01.04.2015, p. 225-229.
  • "Lgg4 immunostaining and its implications in orbital inflammatory disease." PLoS One In: , Vol. 9, No. 10, e10984, 10.10.2014.
  • "Impact of IL-1 signalling on experimental uveitis and arthritis." Annals of the Rheumatic Diseases In: , Vol. 71, No. 5, 05.2012, p. 753-760.
  • "The NLRP3 inflammasome is active but not essential in endotoxin-induced uveitis." Inflammation Research In: , Vol. 61, No. 3, 03.2012, p. 225-231.
  • "The effects of corneal endothelium on graft survival in a murine model of lamellar keratoplasty." Ophthalmic Research In: , Vol. 47, No. 3, 03.2012, p. 128-134.
  • "Differential expression of microRNA and predicted targets in pulmonary sarcoidosis." Biochemical and Biophysical Research Communications In: , Vol. 417, No. 2, 13.01.2012, p. 886-891.
  • "Investigation of the differential potentials of TLR agonists to elicit uveitis in mice." Journal of Leukocyte Biology In: , Vol. 90, No. 6, 12.2011, p. 1159-1166.
  • "Contrasting Ocular Effects of Local versus Systemic Endotoxin." Investigative Ophthalmology and Visual Science In: , Vol. 52, No. 9, 08.2011, p. 6472-6477.
  • "NLRs in immune privileged sites." Current Opinion in Pharmacology In: , Vol. 11, No. 4, 08.2011, p. 423-428.
  • "Endotoxin-induced uveitis is primarily dependent on radiation-resistant cells and on MyD88 but not TRIF." Journal of Leukocyte Biology In: , Vol. 90, No. 2, 08.2011, p. 305-311.
  • "The expression of STAT-1 and phosphorylated STAT-1 in conjunctival granulomas." Ocular Immunology and Inflammation In: , Vol. 18, No. 4, 08.2010, p. 261-264.
  • "Nucleotide-binding oligomerization domain 2 and toll-like receptor 2 function independently in a murine model of arthritis triggered by intraarticular peptidoglycan." Arthritis and Rheumatism In: , Vol. 62, No. 4, 04.2010, p. 1051-1059.
  • "Epifluorescence intravital microscopy of murine corneal dendritic cells." Investigative Ophthalmology and Visual Science In: , Vol. 51, No. 4, 04.2010, p. 2101-2108.
  • "Nucleotide oligomerization domain-2 interacts with 2′-5′-oligoadenylate synthetase type 2 and enhances RNase-L function in THP-1 cells." Molecular Immunology In: , Vol. 47, No. 2-3, 12.2009, p. 560-566.
  • "Insights in to the pathogenesis of axial spondyloarthropathy based on gene expression profiles." Arthritis Research and Therapy In: , Vol. 11, No. 6, R168, 09.11.2009.
  • "Hypothesis : Sarcoidosis is a STAT1-mediated disease." Clinical Immunology In: , Vol. 132, No. 2, 08.2009, p. 174-183.
  • "Feasibility study of lamellar keratoplasty in a murine model." Ocular Immunology and Inflammation In: , Vol. 17, No. 4, 08.2009, p. 257-264.
  • "Activation of nucleotide oligomerization domain 2 exacerbates a murine model of proteoglycan-induced arthritis." Journal of Leukocyte Biology In: , Vol. 85, No. 4, 01.04.2009, p. 711-718.
  • "NOD1 expression in the eye and functional contribution to IL-1β-dependent ocular inflammation in mice." Investigative Ophthalmology and Visual Science In: , Vol. 50, No. 4, 04.2009, p. 1746-1753.
  • "Nucleotide oligomerization domain-2 (NOD2)-induced uveitis : Dependence on IFN-γ." Investigative Ophthalmology and Visual Science In: , Vol. 50, No. 4, 04.2009, p. 1739-1745.
  • "The NOD2 defect in Blau syndrome does not result in excess interleukin-1 activity." Arthritis and Rheumatism In: , Vol. 60, No. 2, 02.2009, p. 611-618.
  • "Gene expression profiling of whole blood : Comparison of target preparation methods for accurate and reproducible microarray analysis." BMC Genomics In: , Vol. 10, 2, 05.01.2009.
  • "Application of biostatistics and bioinformatics tools to identify putative transcription factor-gene regulatory network of ankylosing spondylitis and sarcoidosis." Communications in Statistics - Theory and Methods In: , Vol. 38, No. 18, 2009, p. 3326-3338.
  • "Activation of NOD2 in vivo induces IL-1β production in the eye via caspase-1 but results in ocular inflammation independently of IL-1 signaling." Journal of Leukocyte Biology In: , Vol. 84, No. 2, 01.08.2008, p. 529-536.

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