The overarching mission of the OHSU Department of Cell, Developmental & Cancer Biology is to advance the understanding of problems relevant to human health and disease. To accomplish this mission, research groups in the department have historically focused on questions regarding cell structure, organelles, life cycle, differentiation, and regulated communication between cells and extracellular signals and cues. An ultimate application of knowledge gained from these studies has been to understand important cell physiologic processes that effect human biology. These issues directly link to problems of interest to developmental biologists, including molecular and cellular mechanisms regulating tissue morphogenesis, tissue polarity and patterning. Read full welcome message here.
Welcoming new members during modified operations
Many new faces have joined us since OHSU's modified operations began in March 2020. We have created a page where you will find a photo and bio for faculty, staff, and students who have joined during this time. Visit the page here.
OHSU Respect For All Flowchart
Quantitative and Systems Biology Program Symposium
A series of short talks highlighting both the diversity and commonalities among quantitative work at OHSU. Speakers will be drawn from a range of disciplines. September 20th, 2021 from 9:00am - 12:30pm. More details to come.
At AACR's Tumor Immunology and Immunotherapy event in November, CDCB research presented their research.
Recent Accolades & Funding
Congratulations to Sarah Bernhardt, Ph.D., who is a postdoctoral scholar in the Schedin lab, who has been awarded a Prevent Cancer Foundation Fellowship.
Congratulations to Karin Rodland, Ph.D. who has recently received the PNNL Lab Director’s Award for Lifetime Achievement in Science or Technology.
Congratulations to Missy Wong, Ph.D. and the Wong lab whose paper, "Relevance of circulating hybrid cells as a non-invasive biomarker for myriad solid tumors," published in Scientific Reports is the School of Medicine's Paper of the Month. Read the story on OHSU Now.
The Malhotra lab has recently published two articles:
- "Harnessing the predictive power of preclinical models for oncology drug development" in Nature Reviews Drug Discovery.
- "New Selective Inhibitors of ERG Positive Prostate Cancer: ERGi-USU‑6 Salt Derivatives" in ACS Medicine Chemistry Letters.
The Schedin lab has three publications to announce:
- "Immune Milieu Established by Postpartum Liver Involution Promotes Breast Cancer Liver Metastasis" in MDPI Cancers.
- "The definition of pregnancy-associated breast cancer is outdated and should no longer be used," in The lancet Oncology journal.
- "Vitamin D as a Potential Preventive Agent For Young Women's Breast Cancer" in Cancer Prevention Research.
View all CDCB news and recognitions.
CDCB is pleased to announce that Tanaya Shree, Ph.D., will be joining us as an assistant professor. Dr. Shree is a lymphoma specialist and cancer immunologist. Her lab will focus on dissecting the interplay between the immune system and cancer – understanding immune deficiencies in cancer patients and developing novel strategies for activating the immune system against cancer. Welcome, Dr. Shree!
CDCB is pleased to welcome Katelyn Byrne, Ph.D., who will be joining us as a joint faculty along with the Brendon-Colson Center for Pancreatic Care and the Knight Cancer Institute. The main focus of the Byrne Lab is to investigate the immunobiology of the pancreatic tumor microenvironment, with the long-term goal of generating novel therapies for enhancing immune responses in patients. Welcome, Dr. Byrne!
Congratulations to Elaine Huang, M.S. who has recently been promoted to lab manager for the Coussens lab!
CDCB is excited to welcome Sanjay Malhotra, Ph.D. Dr. Malhotra is joining us as a professor and will co-lead the Knight Cancer Institute's new center, the Center for Experimental Therapeutics. Dr. Malhotra's background is in chemical biology and drug development with a strong expertise in medicinal chemistry, including small molecule synthesis. Visit the Malhotra lab website to learn more. Welcome, Dr. Malhotra!