The overarching mission of the OHSU Department of Cell, Developmental & Cancer Biology is to advance the understanding of problems relevant to human health and disease. To accomplish this mission, research groups in the department have historically focused on questions regarding cell structure, organelles, life cycle, differentiation, and regulated communication between cells and extracellular signals and cues. An ultimate application of knowledge gained from these studies has been to understand important cell physiologic processes that effect human biology. These issues directly link to problems of interest to developmental biologists, including molecular and cellular mechanisms regulating tissue morphogenesis, tissue polarity and patterning. Read full welcome message here.
Welcoming new members during modified operations
Many new faces have joined us since OHSU's modified operations began in March 2020. We have created a page where you will find a photo and bio for faculty, staff, and students who have joined during this time. Visit the page here.
OHSU Respect For All Flowchart
CDCB held its annual picnic this past Monday, September 11th at Laurelhurst Park. We spent the afternoon among good company enjoying tamales & tacos, alongside some furry friends! See more photos here.
Congratulations to Dr. Pepper Schedin, Professor of Cell, Developmental & Cancer Biology, who has been appointed the inaugural recipient of the Leonard Schnitzer Chair in Breast Oncology. The Leonard Schnitzer Family established this endowed chair in Leonard’s memory to help advance clinically relevant cancer research and the work of the OHSU Knight Cancer Institute to end cancer as we know it. An investiture ceremony will be held later this summer to honor the family and Schedin. Read more here.
In recognition of her scientific work and contributions to the field of cancer research, Lisa Coussens, Ph.D. was elected to the National Academy of Sciences, among 143 other newly elected members. Membership is a widely recognized mark of excellence in science, and one of the highest honors that a scientist in the United States can receive. Congratulations, Dr. Coussens! Read more on OHSU Now.
Recent Accolades & Funding
Congratulations to Michelle Ozaki, graduate student in the Schedin lab, who has been award a prestigious F99 award from the NIH that provides funding for 2 years of graduate work and 3 years of postdoc support. The title of her project is, "Fibroblasts in the establishment of the liver pre-metastatic niche."
Congratulations to Dr. Caroline Enns who has recently been received the Marcel Simon Award. The award is presented every two years at the Bioiron Society meeting and is awarded for excellence in the research of genetic hemochromatosis.
Congratulations to Tori Schuster, graduate student in the Ruhland lab, has received a T32 training grant award for Interdisciplinary Training in Microbial Pathogenesis and Immunology.
The Wong lab has 2 publications to announce:
- "Flexible Cyclic Immunoflorescence (cyCIF) Using Oligonucleotide Barcoded Antibodies" in Cancers.
- “The Hallmarks of Circulating Hybrid Cells” editorial in Springer Nature.
- "Increased glucose availability sensitizes pancreatic cancer to chemotherapy" in Nature Communications.
- "Limited nutrient availability in the tumor microenvironment renders pancreatic tumors sensitive to allosteric IDH1 inhibitors" in Nature Cancer.
The Pucci lab has recently published, "Sequential chromogenic immunohistochemistry: spatial analysis of lymph nodes identifies contact interactions between plasmacytoid dendritic cells and plasmablasts" in AACR's Cancer Research Communications.
View all CDCB news and recognitions.
CDCB is pleased to announce that Molly Thomas, M.D., Ph.D., will be joining us as an Assistant Professor in the Department of Cell, Developmental & Cancer Biology, with a joint appointment in the Division of Gastroenterology. Dr. Thomas is an inflammatory bowel disease specialist and mucosal immunologist. Her lab will focus on understanding gastrointestinal and hepatic complications of immune checkpoint blockade and how these immune related adverse events inform our understanding of tissue-resident memory T cells in these organ systems. Welcome, Dr. Thomas!
CDCB is please to welcome Joshua Moreau, Ph.D., who will be joining us as a joint faculty along with the Division of Oncological Sciences, Department of Dermatology, and a member of CEDAR. He aims to explore the earliest interactions between cancer and the immune system, within the tissues where cancer cells arise. Welcome, Dr. Moreau!
CDCB is excited to welcome Megan Burger, Ph.D. who will be joining us as an Assistant Professor in the Department of Cell, Developmental & Cancer Biology, with a joint appointment in the Division of Hematology Oncology. Dr. Burger's research program will initially be investigating the interplay of anti-tumor T cell responses in thoracic malignancies with the goal of identifying targets for new therapy. Welcome, Dr. Burger!