Recent Publications:

The Malhotra Lab published, "Novel Aza-podophyllotoxin derivative induces oxidative phosphorylation and cell death via AMPK activation in triple-negative breast cancer" in the British Journal of Cancer. Read the paper here.

The Mills Lab published has two recent publications: 

• "Large-Scale Characterization of Drug Responses of Clinically Relevant Proteins in Cancer Cell Lines" in Cancer Cell. Read the paper here.

• "Differential expression of MAGEA6 toggles autophagy to promote pancreatic cancer progression" in Elife. Read the paper here.

The Schedin Lab published, "Characterization of weaning-induced breast involution in women: implications for young women’s breast cancer," in NPJ Breast Cancer. Read the paper here.

The Oshimori Lab published, "Cancer stem cells and their niche in the progression of squamous cell carcinoma," in Cancer Science. Read the paper here.

CDCB's Dr. Evan Lind and members of the Lind lab recently published, "Reversible suppression of T cell function in the bone marrow microenvironment of acute myeloid leukemia," in the Proceedings of the National Academy of Sciences of the United States of America. The paper has also been named the "Paper of the Month" by the OHSU School of Medicine. Read the paper here.

A group of OHSU researchers, including CDCB's Dr. Amy Moran, recently published, "A phase II single-arm study of pembrolizumab with enzalutamide in men with metastatic castration-resistant prostate cancer progressing on enzalutamide alone," in the Journal of ImmunoTherapy of Cancer. Read the paper here.

The Sherman Lab published, "Acidic fibroblast growth factor underlies microenvironmental regulation of MYC in pancreatic cancer," in the Journal of Experimental Medicine. Read the paper here.

The Pucci Lab published, "Cell Surface Labeling by Engineered Extracellular Vesicles," in Advanced Biosystems. Read the paper here.

The Oshimori Lab published, "Tumor-initiating cells establish an IL-33–TGF-β niche signaling loop to promote cancer progression," in Science magazine. Read the paper here.

The Schedin lab's Dr. Sonali Jindal published, "Comparison of Mortality Among Participants ofWomen’s Health Initiative Trials With Screening-Detected Breast Cancers vs Interval Breast Cancers," in JAMA Network Open. Read the paper here. 

The Schedin lab's Dr. Elizabeth Mitchell published, "Loss of myoepithelial calponin‐1 characterizes high‐risk ductal carcinoma in situ cases, which are further stratified by T cell composition, in Molecular Carcinogenesis." Read the paper here.

The Walker Lab published, NKTR-214 immunotherapy synergizes with radiotherapy to stimulate systemic CD8+ T cell responses capable of curing multi-focal cancer, in the Journal for ImmunoTherapy of Cancer which was featured in the spotlight of ACIR's June 11 2020 Weekly Digest.

The Enns Lab has three recent publications: 

• "The Ectodomain of Matriptase-2 Plays an Important Non-Proteolytic Role in Suppressing Hepcidin Expression in Mice" in Blood. Read the paper here. 

• "Insights into basic science: what basic science can teach us about iron homeostasis in trauma patients" in Current Opinion in Anesthesiology. Read the review here.

• "Extrahepatic deficiency of transferrin receptor 2 is associated with increased erythropoiesis independent of iron overload" in the Journal of Biological Chemistry. Read the paper here.

Recent Accolades/Funding:

Congratulations to Samuel Tsang, Ph.D. (Research Assistant Professor, Mills lab) and Aurora Blucher, Ph.D. (Postdoctoral Scholar, Mills lab) who are both OHSU Center for Women’s Health Circle of Giving 2020 awardees.

Congratulations to Amy Moran, Ph.D. whose invited presentation at the Immuno-Oncology Young Investigator's Forum won first place in the research scientist category. Her talk focused on work revealing how androgen receptor activity is a critical determinant of checkpoint blockade efficacy.

Congratulations to the OHSU Knight Cancer Institute's Center for Experimental Therapeutics, directed by Sanjay Malhtora, Ph.D., which has been awarded one of eleven grants from the Indo-U.S. Science and Technology Forum (IUSSTF) to form a virtual network for COVID-19 research. 

Congratulations to Michelle Ozaki, graduate student in the Schedin Lab, who recently received the ACRS Scholar Award and was one of three OHSU students to receive a 2020 National Science Foundation Graduate Research Fellowship.

Congratulations to Philip Copenhaver, Ph.D. who was recently awarded a five-year RF1 grant to investigate how signaling by the Amyloid Precursor Protein (APP) controls neuronal guidance within the developing nervous system.

Congratulations to Mara Sherman, Ph.D. who is the recipient of a Pew Scholar award. As part of the 2020 class of the Pew-Stewart Scholars Program for Cancer Research, Dr. Sherman will receive a four-year grant to advance innovative research into the development, diagnosis, and treatment of cancer. Learn more here.

Congratulations to Adrian Baris (Anand Lab) and Reed Hawkins (Moran Lab), two CDCB students who have each received a training grant from the NIH Ruth L Kirschstein T32 Program in Enhanced Research Training (PERT), and will spend one year in intensive training that emphasizes the competencies they will need to develop a successful career in biomedical research.

The OHSU School of Medicine's Office of Graduate Studies has released the 2020 report of career outcomes for its 518 PhD recipients, including Cancer Biology and Cell & Developmental Biology program graduates. Read the report here.

CDCB's Philip Copenhaver, Ph.D. and his fourth-year M.D. mentee, Eric Nomura, were featured in OHSU News article "Scholarly projects showcase student creativity from the heart", which explores how the pair developed Eric's capstone project.

View all CDCB news and recognitions.