OCTRI is a catalyst for scientific collaboration, translation of biomedical advances into the community, innovation and research growth. With major funding from the National Institutes of Health through the Clinical and Translational Science Awards, and significant institutional commitment from OHSU, our mission is to improve human health by enhancing clinical and translational research.
OCTRI at a glance
OCTRI supports investigators, administrators and research staff with expertise, equipment and facilities. From catalyzing research to fostering scientific partnerships, we support critical stages of the clinical and translational research process. Review the diagram below or read this pdf for details on our strategic goals.
Clinical and Translational Science Awards consortium
OCTRI belongs to a national consortium established in 2006 when the National Center for Research Resources awarded 12 academic health centers with the Clinical and Translational Science Awards. Since then, the consortium has expanded to include 61 institutions linked together to energize the discipline of clinical and translational science. As one of the original 12 awardees, OCTRI continues to play an instrumental role in this collaborative work.
Consortium members share a common vision to improve human health by transforming the research and training environment to enhance the efficiency and quality of clinical and translational research.
Translational research—a pathway to better human health
OCTRI's mission is to improve human health by enhancing clinical and translational research. In order to maximize the positive impact that research has on human health, the scientific discoveries happening in labs all over the world must be translated into practical tools and knowledge. This is the simplest explanation of translational research – moving scientific discoveries into applications that affect human health.
The concept of "translational research" is relatively new, and the scientific community is engaged in vibrant discussions through journals, blogs, opinion pieces and meetings about the definition and scope of translational research. The original Request for Applications for the CTSA program defined translational research.
Translational research includes two areas of translation:
The process of applying discoveries generated during research in the laboratory and in preclinical studies, to the development of trials and studies in humans.
Research aimed at enhancing the adoption of best practices in the community.
Movement and activity along the spectrum of translational research go both ways. Basic scientists offer findings that result in new tools for use with patients or changes in diagnostic processes, and clinicians make observations that inform research questions in the laboratory. Epidemiologists often translate their findings into health policy, and their findings also inform the work of clinical researchers — another example of the translational process going both ways.